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公开(公告)号：EP1349935A2
公开(公告)日：2003-10-08
申请号：EP02709031.5
申请日：2002-01-09
发明人： PANZER, Scott, R. , LINCOLN, Stephen, E. , ALTUS, Christina, M. , DUFOUR, Gerard, E. , JACKSON, Jennifer, L. , JONES, Anissa, L. , DAM, Tam, C. , LIU, Tommy, F. , HARRIS, Bernard , FLORES, Vincent , DAFFO, Abel , MARWAHA, Rakesh , CHEN, Alice, J. , CHANG, Simon, C. , GERSTIN, Edward, H., Jr. , PERALTA, Careyna, H. , DAVID, Marie, H. , LEWIS, Samantha, A.
CPC分类号： C07K16/18 , A01K2217/05 , C07K14/47
摘要： The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce antibodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.
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公开(公告)号：EP1366166A2
公开(公告)日：2003-12-03
申请号：EP02733781.5
申请日：2002-01-09
发明人： PANZER, Scott, R. , LINCOLN, Stephen, E. , ALTUS, Christina, M. , DUFOUR, Gerard, E. , HILLMAN, Jennifer, L. , JONES, Anissa, L. , DAM, Tam, C. , LIU, Tommy, F. , HARRIS,Bernard , FLORES, Vincent , DAFFO, Abel , MARWAHA, Rakesh , CHEN, Alice, J. , CHANG, Simon, C. , GERSTIN, Jr., Edward, H , PERALTA, Careyna, H. , DAVID, Marie, H. , LEWIS, Samantha, A.
IPC分类号： C12N15/12 , C07K14/47 , C12Q1/68 , C12N5/10 , C12N1/21 , A01K67/027 , C12N15/00 , A61K38/16 , C07K16/18 , G01N33/68
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00
摘要： The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP .The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.
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公开(公告)号：EP1409504A2
公开(公告)日：2004-04-21
申请号：EP02739118.4
申请日：2002-03-27
发明人： DAFFO, Abel , JONES, Anissa, L. , TRAN, Alanna-Phung, B. , DAHL, Christopher, R. , GIETZEN, Darryl , CHINN, Joyce , DUFOUR, Gerard, E. , JACKSON, Jennifer, L. , YU, Jimmy, Y. , TUASON, Olivia , YAP, Pierre, E. , AMSHEY, Stefan, R. , DAUGHTERY, Sean, C. , DAM, Tam, C. , LIU, Tommy, F. , NGUYEN, Duy-Viet, An , KLEEFELD, Yael , GERSTIN, Edward, H., Jr. , PERALTA, Careyna, H. , DAVID, Marie H. , LEWIS, Samantha A. , CHEN, Alice J. , PANZER, Scott R. , HARRIS, Bernard , MULLAHY-FLORES, Vincent Z. , MARWAHA, Rakesh , LO, Audrey , LAN, Ruth Y. , URASHKA, Michael E.
IPC分类号： C07H21/00
CPC分类号： C07K14/47
摘要： The invention provides purified secretory polynucleotides (sptm). Also encompassed are the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTMto induce antibodies and to screen libraries of compounds and the use of anti-SPTM antibodies in diagnostic assays. Also provided are microarrays containing sptm and methods of use.
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公开(公告)号：EP1383894A2
公开(公告)日：2004-01-28
申请号：EP02744104.7
申请日：2002-03-27
发明人： DAFFO, Abel , JONES, Anissa, L. , TRAN, Alanna-Phung, B. , DAHL, Christopher, R. , GIETZEN, Darryl , CHINN, Joyce , DUFOUR, Gerard, E. , HILLMAN, Jennifer, L. , YU, Jimmy, Y. , TUASON, Olivia , YAP, Pierre, E. , AMSHEY, Stefan, R. , DAUGHERTY, Sean, C. , DAM, Tam, C. , LIU, Tommy, F. , NGUYEN, Duy-Viet, An , KLEEFELD, Yael , GERSTIN, Edward, H., Jr. , PERALTA, Careyna, H. , DAVID, Marie H. , LEWIS, Samantha A. , CHEN, Alice J. , PANZER, Scott R. , HARRIS, Bernard , MULLAHY-FLORES, Vincent , MARWAHA, Rakesh , LO, Audrey , LAN, Ruth Y. , URASHKA, Michael E.
IPC分类号： C12N15/12 , C12Q1/68 , C07K14/435
CPC分类号： C07K14/47
摘要： The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce antibodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.
摘要翻译： 本发明提供了纯化的疾病检测和治疗分子多核苷酸（mddt）。 还包括由mddt编码的多肽（MDDT）。 本发明还提供了mddt或其互补物，寡核苷酸或其片段在诊断测定中的用途。 本发明进一步提供了用于表达MDDT的含有mddt的载体和宿主细胞。 本发明另外提供了使用分离和纯化的MDDT诱导抗体并筛选化合物文库和抗MDDT抗体在诊断测定中的用途。 还提供了含有mddt和使用方法的微阵列。
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公开(公告)号：EP1268758A2
公开(公告)日：2003-01-02
申请号：EP00938123.7
申请日：2000-05-31
发明人： HODGSON, David, M , LINCOLN, Stephen, E. , RUSSO, Frank, D. , SPIRO, Peter A. , BANVILLE, Steven, C. , BRATCHER, Shawn, R. , DUFOUR, Gerard, E. , COHEN, Howard, J. , ROSEN, Bruce, H. , CHALUP, Michael, S. , HILLMAN, Jennifer, L. , JONES, Anissa, L. , YU, Jimmy, Y. , GREENAWALT, Lila, B. , PANZER, Scott, R. , ROSEBERRY, Ann, M. , WRIGHT, Rachel, J. , DANIELS, Susan, E.
CPC分类号： C12Q1/6876 , C12Q1/6834 , C12Q2600/158
摘要： The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP. The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.
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