公开(公告)号：EP1436383A2

公开(公告)日：2004-07-14

申请号：EP02725148.7

申请日：2002-03-05

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  YANG, Jumming ,  ELLIOTT, Vicki, S. ,  DUGGAN, Brendan, M. ,  HONCHELL, Cynthia, D. ,  LEE, Sally ,  THANGAVELU, Kavitha ,  GIETZEN, Kimberly, J. ,  FORSYTHE, Ian, J. ,  LU, Dyung, Aina, M. ,  GRIFFIN, Jennifer, A. ,  GURURAJAN, Rajagopal ,  LAL, Preeti, G. ,  BAUGHN, Mariah, R. ,  XU, Yuming ,  TANG, Y., Tom ,  AZIMZAI, Yalda ,  AU-YOUNG, Janice ,  KALLICK, Deborah, A. ,  CHAWLA, Narinder, K. ,  MASON, Patricia, M. ,  TRAN, Uyen, K.

IPC分类号： C12N9/04 ,  C12Q1/32 ,  A01N37/18

CPC分类号： C07K14/47 ,  A61K38/00 ,  C12N9/6421

摘要： The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

公开(公告)号：EP1409550A1

公开(公告)日：2004-04-21

申请号：EP02739996.3

申请日：2002-06-26

申请人： Incyte Genomics, Inc.

发明人： DELEGEANE, Angelo, M. ,  BOROWSKY, Mark, L. ,  KHAN, Farrah, A. ,  KEARNEY, Liam ,  RAMKUMAR, Jayalaxmi ,  CHAWLA, Narinder, K. ,  LU, Yan ,  HONCHELL, Cynthia, D. ,  KALLICK, Deborah, A. ,  EMERLING, Brooke, M. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  WARREN, Bridget, A. ,  YUE, Henry ,  THANGAVELU, Kavitha ,  SPRAGUE, William, W. ,  ISON, Craig, H. ,  ELLIOTT, Vicki, S. ,  MASON, Patricia, M. ,  RICHARDSON, Thomas W. ,  TRAN, Uyen K. ,  SWARNAKAR, Anita ,  JIN, Pei ,  KABLE, Amy E.

IPC分类号： C07K17/00

CPC分类号： C07K14/47 ,  A61K38/00

摘要： Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.

公开(公告)号：EP1423697A2

公开(公告)日：2004-06-02

申请号：EP02728613.7

申请日：2002-03-29

申请人： Incyte Genomics, Inc.

发明人： BAUGHN, Mariah, R. ,  BURFORD, Neil ,  DING, Li ,  DUGGAN, Brendan, M. ,  ELLIOTT, Vicki, S. ,  FORSYTHE, Ian, J. ,  GANDHI, Ameena, R. ,  GIETZEN, Kimberly, J. ,  GRIFFIN, Jennifer, A. ,  HE, Ann ,  HONCHELL, Cynthia, D. ,  ISON, Craig, H. ,  LAL, Preeti, G. ,  LEE, Ernestine, A. ,  LEE, Sally ,  LU, Dyung Aina, M. ,  MASON, Patricia, M. ,  SANJANWALA, Madhu, M. ,  SWARNAKAR, Anita ,  RAMKUMAR, Jayalaxmi ,  TANG, Y. Tom ,  THANGAVELU, Kavitha ,  TRAN, Uyen K. ,  CHAWLA, Narinder K. ,  WARREN, Bridget A. ,  YOA, Monique G. ,  XU, Yuming ,  YUE, Henry

IPC分类号： G01N33/53 ,  C12P21/06 ,  A61K38/00 ,  C07K14/00

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00

摘要： The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

公开(公告)号：EP1461443A2

公开(公告)日：2004-09-29

申请号：EP02734761.6

申请日：2002-05-22

申请人： Incyte Genomics, Inc.

发明人： SWARNAKAR, Anita ,  GORVAD, Ann, E. ,  HAFALIA, April, J., A. ,  DUGGAN, Brendan, M. ,  EMERLING, Brooke, M. ,  ISON, Craig, H. ,  NGUYEN, Danniel, B. ,  LEE, Ernestine, A. ,  YUE, Henry ,  YUE, Huibin ,  FORSYTHE, Ian, J. ,  LI, Joana, X. ,  THANGAVELU, Kavitha ,  CHAWLA, Narinder, K. ,  BURFORD, Neil ,  MASON, Patricia, M. ,  LAL, Preeti, G. ,  LEE, Sally ,  BECHA, Shanya, D.

IPC分类号： C12P21/06 ,  C12N5/00 ,  C12N15/00 ,  C12N15/63 ,  C07H21/02 ,  C07H21/04

CPC分类号： C07K14/47 ,  A61K38/00

摘要： The invention provides human carbohydrate-associated proteins (CHOP) and polynucleotides which identify and encode CHOP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CHOP.

公开(公告)号：EP1409655A2

公开(公告)日：2004-04-21

申请号：EP02726671.7

申请日：2002-03-12

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  XU, Yuming ,  THANGAVELU, Kavitha ,  WARREN, Bridget, A. ,  TANG, Y., Tom ,  DUGGAN, Brendan, M. ,  TRAN, Uyen, K. ,  BAUGHN, Mariah, R. ,  HONCHELL, Cynthia, D. ,  BURFORD, Neil ,  FORSYTHE, Ian, J. ,  YANG, Junming ,  MASON, Patricia, M.

IPC分类号： C12N9/00 ,  C12N15/00 ,  C12N15/63 ,  C12N15/85 ,  C07H21/04 ,  C07K17/00

CPC分类号： C07K14/70503 ,  A01K2217/05 ,  A61K38/00 ,  A61K2039/505

摘要： The invention provides human immunoglobulin superfamily proteins (IGSFP) and polynucleotides which identify and encode IGSFP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of IGSFP.

摘要翻译： 本发明提供了鉴定和编码IGSFP的人免疫球蛋白超家族蛋白（IGSFP）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与IGSFP异常表达相关的病症的方法。