公开(公告)号：EP1432801A2

公开(公告)日：2004-06-30

申请号：EP02720945.1

申请日：2002-02-05

申请人： Incyte Genomics, Inc.

发明人： AZIMZAI, Yalda ,  YUE, Henry ,  DING, Li ,  NGUYEN, Danniel B. ,  GANDHI, Ameena R. ,  BURFORD, Neil ,  THANGAVELU, Kavitha ,  ELLIOTT, Vicki S. ,  RAMKUMAR, Jayalaxmi ,  YAO, Monique, G. ,  LAL, Preeti G. ,  TANG, Tom Y. ,  SWARNAKAR, Anita ,  WARREN, Bridget A. ,  CHAWLA, Narinder K. ,  POLICKY, Jennifer L. ,  XU, Yunming ,  HONCHELL, Cynthia D. ,  AU-YOUNG, Janice ,  BAUGHN, Mariah R. ,  DUGGAN, Brendan M. ,  LU, Dyung Aina M. ,  GIETZEN, Kimberly J. ,  JACKSON, Jennifer L. ,  RAUMANN, Bridget E. ,  Lu, Yan ,  KAREHT, Stephanie K. ,  TRAN, Uyen K. ,  RICHARDSON, Thomas W. ,  EMERLING, Brook M. ,  HAFALIA, April J. A. ,  BURRILL, John D. ,  MARCUS, Gregory A. ,  ZINGLER, Kurt A. ,  KABLE, Amy E. ,  GORVARD, Ann E.

IPC分类号： C12N15/12

CPC分类号： C07K14/47 ,  C07K14/705

摘要： The invention provides human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.

摘要翻译： 本发明提供了识别和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与REMAP异常表达相关的病症的方法。

公开(公告)号：EP1578902A2

公开(公告)日：2005-09-28

申请号：EP02761662.2

申请日：2002-09-12

申请人： Incyte Genomics, Inc.

发明人： HONCHELL, Cynthia, D. ,  WARREN, Bridget, A. ,  BOROWSKY, Mark, L. ,  GRIFFIN, Jennifer, A. ,  LI, Joana, X. ,  LEE, Soo, Yeun ,  YUE, Henry ,  FORSYTHE, Ian, J. ,  MARQUIS, Joseph, P. ,  GIETZEN, Kimberly, J. ,  BAUGHN, Mariah, R. ,  TRAN, Uyen, K. ,  LEHR-MASON, Patricia, M. ,  TANG, Y., Tom ,  RAMKUMAR, Jayalaxmi ,  EMERLING, Brooke, M. ,  LEE, Ernestine, A. ,  ELLIOTT, Vicki, S. ,  HAFALIA, April, J.A. ,  DUGGAN, Brendan M. ,  CHAWLA, Narinder K. ,  KABLE, Amy E. ,  CHANG, Hsin-Ru ,  KHARE, Reena ,  BECHA, Shanya D. ,  JIN, Pei ,  LEE, Sally

IPC分类号： C12N1/00

CPC分类号： C07K14/705 ,  A01K2217/05 ,  A61K38/00 ,  C07K14/47 ,  C07K14/475 ,  C07K14/78 ,  C07K2319/00

摘要： Various embodiments of the invention provide human neurotransmission-associated proteins (NTRAN) and polynucleotides which identify and encode NTRAN. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NTRAN.

公开(公告)号：EP1390410A1

公开(公告)日：2004-02-25

申请号：EP02739428.7

申请日：2002-05-24

申请人： Incyte Genomics, Inc.

发明人： TANG, Tom, Y. ,  YUE, Henry ,  BAUGHN, Mariah, R. ,  DUGGAN, Brendan, M. ,  WARREN, Bridget, A. ,  BANDMAN, Olga ,  RICHARDSON, Thomas, W. ,  BURFORD, Neil ,  SANJANWALA, Bharati ,  BECHA, Shanya, D. ,  YAO, Monique, G. ,  YANG, Junming ,  TRAN, Uyen, K. ,  HAFALIA, April, J.A. ,  GRIFFIN, Jennifer, A. ,  SWARNAKAR, Anita ,  ELLIOTT, Vicki, S. ,  RECIPON, Shirley, A. ,  KHAN, Farrah, A. ,  LEE, Ernestine A. ,  YUE, Huibin ,  LU, Dyung Aina M. ,  CHAWLA, Narinder K. ,  THANGAVELU, Kavitha ,  ARVIZU, Chandra S. ,  XU, Yuming ,  ISON, Craig H. ,  HUANG, Jiaqi ,  DING, Li ,  HONCHELL, Cynthia D. ,  BOROWSKY, Mark L. ,  EMERLING, Brooke M. ,  PETERSON, David P. ,  LU, Yan ,  RAMKUMAR, Jayalaxmi ,  MASON, Patricia M. ,  ZEBARJADIAN, Yeganeh ,  AZIMZAI, Yalda ,  STUVE, Laura L. ,  KAMIGAKI, Laura L. ,  BARROSO, Ines ,  LEE, Sally ,  KABLE, Amy E.

IPC分类号： C07K17/00 ,  G01N33/53 ,  A61K39/00

CPC分类号： G01N33/5008 ,  A61K38/00 ,  C07K14/47 ,  C12Q1/6837 ,  C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/68 ,  G01N33/6845 ,  G01N2500/00 ,  G01N2500/04

摘要： The invention provides human molecules for disease detection and treatment (MDDT)and polynucleotides which identify and encode MDDT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methodsfor diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.

公开(公告)号：EP1434860A2

公开(公告)日：2004-07-07

申请号：EP02783990.1

申请日：2002-09-26

申请人： Incyte Genomics, Inc.

发明人： YANG, Junming ,  LU, Dyung Aina, M. ,  YUE, Henry ,  ELLIOTT, Vicki, S. ,  WARREN, Bridget, A. ,  DUGGAN, Brendan, M. ,  FORSYTHE, Ian, J. ,  LEE, Ernestine, A. ,  HAFALIA, April, J.A. ,  RAMKUMAR, Jayalaxmi ,  CHAWLA, Narinder, K. ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  GORVAD, Anne, E. ,  TRAN, Uyen, K. ,  LI, Joana, X. ,  YAO, Monique, G. ,  ISON, Craig, H. ,  GRIFFIN, Jennifer, A. ,  CHANG, Hsin-Ru ,  EMERLING, Brooke, M. ,  TANG, Y. Tom ,  LAL, Preeti G. ,  KABLE, Amy E. ,  MARQUIS, Joseph P. ,  JIANG, Xin ,  JACKSON, Alan A. ,  ZEBARJADIAN, Yeganeh ,  SWARNAKAR, Anita ,  WILSON, Amy D. ,  JIN, Pei ,  RICHARDSON, Thomas W. ,  BHATIA, Umesh ,  BURRILL, John C. ,  LEE, Sally ,  BLAKE, Julie J. ,  HO, Anne ,  ZHENG, Wenjin ,  GAO, Jing ,  LEE, Soo Yeun

IPC分类号： C12N9/00 ,  C12N9/14 ,  C12N9/16 ,  C07K16/00 ,  C07K1/00

CPC分类号： C07K14/4702 ,  A61K38/00 ,  C12N9/20

摘要： Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.

公开(公告)号：EP1434796A2

公开(公告)日：2004-07-07

申请号：EP02776174.1

申请日：2002-10-03

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  WARREN, Bridget, A. ,  LEHR-MASON, Patricia, M. ,  TRAN, Uyen, K. ,  DUGGAN, Brendan, M. ,  THANGAVELU, Kavitha ,  YANG, Junming ,  XU, Yuming ,  TANG, Tom, Y. ,  CHAWLA, Narinder, K. ,  ELLIOTT, Vicki, S. ,  FORSYTHE, Ian, J. ,  BECHA, Shanya, D. ,  YAO, Monique, G. ,  EMERLING, Brooke, M. ,  GRIFFIN, Jennifer, A. ,  LAL, Preeti, G. ,  ZEBARJADIAN, Yeganeh ,  BAUGHN, Mariah, R. ,  LEE, Ernestine A. ,  LEE, Soo Yeun ,  RAMKUMAR, Jayalaxmi ,  GORVAD, Ann E. ,  KABLE, Amy E. ,  LU, Dyung Aina M. ,  BOROWSKY, Mark L.

IPC分类号： C07K14/475 ,  A61K38/18

CPC分类号： C07K14/47 ,  A01K2217/05 ,  C12N9/6421

摘要： Various embodiments of the invention provide human secreted proteins (SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与SECP的异常表达相关的病症的方法。

公开(公告)号：EP1521822A2

公开(公告)日：2005-04-13

申请号：EP02773383.1

申请日：2002-09-13

申请人： Incyte Genomics, Inc.

发明人： SPRAGUE, William, W. ,  CHAWLA, Narinder, K. ,  WARREN, Bridget, A. ,  TANG, Y., Tom ,  ELLIOTT, Vicki, S. ,  MARQUIS, Joseph, P. ,  LI, Joana, X. ,  GRIFFIN, Jennifer, A. ,  GIETZEN, Kimberly, J. ,  YANG, Junming ,  LU, Dyung Aina, M. ,  EMERLING, Brooke, M. ,  DUGGAN, Brendan, M. ,  RICHARDSON, Thomas, W. ,  LEE, Soo, Yeun ,  RAMKUMAR, Jayalaxmi ,  BECHA, Shanya, D. ,  LEHR-MASON, Patricia, M. ,  SWARNAKAR, Anita ,  TRAN, Uyen K. ,  KABLE, Amy E. ,  HAFALIA, April J.A. ,  KHARE, Reena

IPC分类号： C12N9/00 ,  C07H21/04

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  C12N9/6421

摘要： Various embodiments of the invention provide human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.a.

公开(公告)号：EP1487989A2

公开(公告)日：2004-12-22

申请号：EP02794113.7

申请日：2002-11-25

申请人： Incyte Genomics, Inc.

发明人： TANG, Y., Tom ,  CHAWLA, Narinder, K. ,  LU, Dyung Aina, M. ,  KHAN, Farrah, A. ,  GANDHI, Ameena, R. ,  SWARNAKAR, Anita ,  AZIMZAI, Yalda ,  MARQUIS, Joseph, P. ,  SPRAGUE, William, W. ,  EMERLING, Brooke, M. ,  YUE, Henry ,  BOROWSKY, Mark, L. ,  BECHA, Shanya, D. ,  ISON, Craig, H. ,  ELLIOTT, Vicki, S. ,  HAFALIA, April, J., A. ,  RING, Huijun, Z. ,  WARREN, Bridget, A. ,  GIETZEN, Kimberly, J. ,  TRAN, Uyen K. ,  LEE, Soo Yeun ,  LEE, Ernestine A. ,  RICHARDSON, Thomas W. ,  KABLE, Amy E. ,  BURFORD, Neil ,  LEHR-MASON, Patricia M. ,  GORVARD, Ann E. ,  LEE, Sally ,  BLAKE, Julie J. ,  HONCHELL, Cynthia D. ,  THANGAVELU, Kavitha ,  RAMKUMAR, Jayalaxmi ,  CHIEN, David ,  JIN, Pei ,  CHANG, Hsin-Ru ,  BAUGHN, Mariah R. ,  NGUYEN, Danniel B. ,  KHARE, Reena ,  BHATIA, Umesh ,  BURRILL, John D. ,  HO, Anne ,  ZHENG, Wenjin

IPC分类号： C12P21/06 ,  C12N1/20 ,  C12N15/00 ,  C07H21/02

CPC分类号： C07K14/47

摘要： Various embodiments of the invention provide human molecules for diseasedetection and treatment (MDDT) and polynucleotides which identify and encode MDDT. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.

公开(公告)号：EP1392852A2

公开(公告)日：2004-03-03

申请号：EP02752013.9

申请日：2002-05-31

申请人： Incyte Genomics, Inc. ,  Yue, Henry

发明人： YUE, Henry ,  TANG, Y., Tom ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  WARREN, Bridget, A. ,  WALIA, Narinder, K. ,  LAL, Preeti, G. ,  LEE, Ernestine, A. ,  HAFALIA, April, J.A. ,  RICHARDSON, Thomas, W. ,  GRIFFIN, Jennifer, A. ,  EMERLING, Brooke, M. ,  RAMKUMAR, Jayalaxmi ,  YUE, Huibin ,  SWARNAKAR, Anita ,  TRAN, Bao ,  LI, Joana, X. ,  YAO, Monique, G. ,  YANG, Junming ,  ISON, Craig H. ,  FORSYTHE, Ian J. . ,  HONCHELL, Cynthia D. ,  ARVIZU, Chandra S. ,  ELLIOTT, Vicki S. ,  LU, Yan ,  DING, Li ,  LUO, Wen ,  WANG, Yu-Mei E. ,  BURFORD, Neil ,  BOROWSKY, Mark L. ,  NGUYEN, Danniel B. ,  CHINN, Anna M. ,  KABLE, Amy E.

IPC分类号： C12Q1/48 ,  C12N9/10 ,  A61K38/00

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  C12Q1/6883 ,  C12Q2600/158

摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与NAAP的异常表达相关的病症的方法。

公开(公告)号：EP1481081A2

公开(公告)日：2004-12-01

申请号：EP02736944.6

申请日：2002-05-17

申请人： Incyte Genomics, Inc.

发明人： TANG, Y., Tom ,  YUE, Henry ,  AZIMZAI, Yalda ,  BAUGHN, Mariah, R. ,  BURFORD, Neil ,  REDDY, Roopa ,  WALIA, Narinder, K. ,  DAS, Debopriya ,  NGUYEN, Danniel, B. ,  YAO, Monique, G. ,  ARVIZU, Chandra, S. ,  LU, Yan ,  GANDHI, Ameena, R. ,  GRIFFIN, Jennifer, A. ,  ELLIOTT, Vicki, S. ,  RAMKUMAR, Jayalaxmi ,  LAL, Preeti, G. ,  LU, Dyung Aina, M. ,  LEE, Ernestine, A. ,  LEE, Soo Yeun ,  YUE, Huibin ,  YANG, Junming ,  TRIBOULEY, Catherine M. ,  KABLE, Amy E. ,  SWARNAKAR, Anita

IPC分类号： C12Q1/68 ,  G01N33/53 ,  A61K38/17 ,  C07K14/47 ,  C07K16/18

CPC分类号： C07K14/4702 ,  A61K38/00 ,  C12N9/20

摘要： The invention provides human lipid-associated molecules (LIPAM) and polynucleotides which identify and encode LIPAM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LIPAM.

摘要翻译： 本发明提供了鉴定和编码LIPAM的人类脂质相关分子（LIPAM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与LIPAM异常表达相关的病症的方法。

公开(公告)号：EP1429806A2

公开(公告)日：2004-06-23

申请号：EP02761511.1

申请日：2002-08-22

申请人： Incyte Genomics, Inc.

发明人： DUGGAN, Brendan, M. ,  LEE, Sally ,  BAUGHN, Mariah, R. ,  HAFALIA, April, J.A. ,  CHAWLA, Narinder, K. ,  ELLIOTT, Vicki, S. ,  LEE, Soo, Yeun ,  KHARE, Reena ,  WILSON, Amy, D. ,  JIN, Pei ,  HAWKINS, Phillip, R. ,  TANG, Y., Tom ,  BURFORD, Neil ,  DING, Li ,  YAO, Monique, G. ,  BECHA, Shanya, D. ,  TRAN, Uyen, K. ,  CHIEN, David ,  ZEBARJADIAN, Yeganeh ,  RICHARDSON, Thomas W. ,  KABLE, Amy E. ,  CHANG, Hsin-Ru ,  SWARNAKAR, Anita ,  LEHR-MASON, Patricia M. ,  RAMKUMAR, Jayalaxmi

IPC分类号： A61K45/00 ,  C07K14/00 ,  C12P21/04

CPC分类号： C07K14/47

摘要： Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码EXMES的人细胞外信使（EXMES）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与EXMES的异常表达相关的病症的方法。