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公开(公告)号:EP1442064A2
公开(公告)日:2004-08-04
申请号:EP02801802.6
申请日:2002-10-17
发明人: BANDMAN, Olga , BAUGHN, Mariah, R. , BECHA, Shanya, D. , BOROWSKY, Mark, L. , DUGGAN, Brendan, M. , EMERLING, Brooke, M. , FORSYTHE, Ian, J. , GANDHI, Ameena, R. , GORVAD, Ann, E. , GRIFFIN, Jennifer, A. , GURURAJAN, Rajagopal , HAFALIA, April, J.A. , KHAN, Farrah, A. , LAL, Preeti, G. , LEE, Ernestine, A. , LEE, Soo, Yeun , LINDQUIST, Erika, A. , LU, Dyung Aina, M. , LU, Yan , MARQUIS, Joseph, P. , NGUYEN, Danniel, B. , ARVIZU, Chandra S. , RAMUKAR, Jayalaxmi , RECIPON, Shirley A. , RICHARDSON, Thomas, W. , SWARNAKAR, Anita , TANG, Y., Tom , THORNTON, Michael , TRAN, Uyen, K. , CHAWLA, Narinder, K. , WARREN, Bridget A. , YANG, Junming , YAO, Monique G. , YUE, Henry , ZEBARJADIAN, Yeganeh
CPC分类号: C12N9/1205 , A01K2217/05
摘要: Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
摘要翻译: 本发明的各种实施方案提供了鉴定和编码KPP的人类激酶和磷酸酶(KPP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供了用于诊断,治疗或预防与KPP异常表达相关的病症的方法。
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公开(公告)号:EP1412387A2
公开(公告)日:2004-04-28
申请号:EP01988245.5
申请日:2001-10-25
发明人: TANG, Y., Tom , YUE, Henry , NGUYEN, Danniel, B. , HAFALIA, April, J., A. , ELLIOTT, Vicki, S. , LU, Yan , CHAWLA, Narinder, K. , YAO, Monique, G. , BAUGHN, Mariah, R. , GANDHI, Ameena, R. , DING, Li , SANJANWALA, Madhusudan , RAMKUMAR, Jayalaxmi , ARVIZU, Chandra , GIETZEN, Kimberly, J. , LAL, Preeti, G. , AZIMZAI, Yalda , KHAN, Farrah, A. , THANGAVELU, Kavitha , THORNTON, Michael , LU, Dyung Aina M. , TRIBOULEY, Catherine M. , WARREN, Bridget A. , ISON, Craig H. , DAS, Debopriya , RAUMANN, Brigitte E. , POLICKY, Jennifer L. , KEARNEY, Liam
IPC分类号: C07K14/705
CPC分类号: C07K14/705
摘要: The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
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公开(公告)号:EP1404703A2
公开(公告)日:2004-04-07
申请号:EP02723697.5
申请日:2002-03-29
发明人: THORNTON, Michael , YAO, Monique, G. , RICHARDSON, Thomas, W. , SWARNAKAR, Anita , KALLICK, Deborah, A. , ISON, Craig, H. , CHAWLA, Narinder, K. , GANDHI, Ameena, R. , LEE, Ernestine, A. , ELLIOTT, Vicki, S. , HAFALIA, April, J.A. , AU-YOUNG, Janice , GRIFFIN, Jennifer, A. , BAUGHN, Mariah, R. , KHAN, Farrah, A. , BECHA, Shanya , LU, Yan , ARVIZU, Chandra, S. , BOROWSKY, Mark, L. , LAL, Preeti G. , RAMKUMAR, Jayalaxmi , EMERLING, Brooke M. , WALSH, Roderick T. , YUE, Henry , BURFORD, Neil , GRAUL, Richard C.
CPC分类号: C07K14/705 , A01K2217/05 , A61K38/00 , A61K2039/505
摘要: The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
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公开(公告)号:EP1373306A2
公开(公告)日:2004-01-02
申请号:EP02757814.5
申请日:2002-03-25
发明人: HAFALIA, April, J., A. , TANG, Tom, Y. , YUE, Henry , KHAN, Farrah, A. , ISON, Craig, H. , BAUGHN, Mariah, R. , WARREN, Bridget, A. , DUGGAN, Brendan, M. , THANGAVELU, Kavitha , HONCHELL, Cynthia, D. , AZIMZAI, Yalda , ELLIOTT, Vicki, S. , BURFORD, Neil , DING, Li , YUE, Huibin , BECHA, Shanya , EMERLING, Brooke, M. , RICHARDSON, Thomas, W. , LEE, Soo, Yeun , BANDMAN, Olga , LAL, Preeti G. , LEE, Sally , GIETZEN, Kimberly J. , CHAWLA, Narinder K. , GRIFFIN, Jennifer A. , LEE, Ernestine A. , SWARNAKAR, Anita , RING, Huijun Z. , JONES, Karen Anne
IPC分类号: C07K14/00
摘要: The invention provides human cytoskeleton-associated proteins (CSAP) and polynucleotides which identify and encode CSAP. The invention also providing expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CSAP.
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公开(公告)号:EP1341921A2
公开(公告)日:2003-09-10
申请号:EP01975504.0
申请日:2001-09-28
发明人: YUE, Henry , BAUGHN, Mariah, R. , WARREN, Bridget, A. , TRIBOULEY, Catherine, M. , TANG, Y., Tom , KHAN, Farrah, A. , YAO, Monique, G. , LAL, Preeti , THORNTON, Michael
IPC分类号: C12N15/55 , C12N9/14 , C07K16/40 , G01N33/573 , G01N33/577 , C12Q1/34 , C12Q1/68 , A61K38/46 , A61K39/395 , C12N1/21 , C12N1/15 , C12N5/10 , A01K67/027 , A01H5/00
CPC分类号: C12N9/14 , A01K2217/05 , A61K38/00 , A61K2039/505
摘要: The invention provides human hydrolases (HYDR) and polynucleotides which identify and encode HYDR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HYDR.
摘要翻译: 本发明提供了识别和编码HYDR的人水解酶(HYDR)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与HYDR异常表达相关的病症的方法。
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公开(公告)号:EP1320550A2
公开(公告)日:2003-06-25
申请号:EP01977315.9
申请日:2001-09-28
发明人: BAUGHN, Mariah, R. , GRAUL, Richard, C. , WALIA, Narinder, K. , GANDHI, Ameena, R. , HAFALIA, April, J., A. , RAMKUMAR, Jayalaxmi , TRIBOULEY, Catherine, M. , THORNTON, Michael , KALLICK, Deborah, A. , YAO, Monique, G. , ELLIOTT, Vicki, S. , BURFORD, Neil , KHAN, Farrah, A. , YUE, Henry , LU, Yan , ARVIZU, Chandra , ROOPA, Reddy , NGUYEN, Danniel, B. , LEE, Ernestine, A. , LU, Dyung Aina M. , ISON, Craig H. , WALSH, Roderick T. , POLICKY, Jennifer L.
IPC分类号: C07K14/705
CPC分类号: C07K14/705
摘要: The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
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公开(公告)号:EP1280918A2
公开(公告)日:2003-02-05
申请号:EP01935320.0
申请日:2001-05-11
发明人: DAS, Debopriya , REDDY, Roopa , YAO, Monique, G. , NGUYEN, Danniel, B. , LU, Yan , TRIBOULEY, Catherine, M. , YUE, Henry , KHAN, Farrah, A. , GANDHI, Ameena, R. , AU-YOUNG, Janice , LAL, Preeti , KEARNEY, Liam , ELLIOTT, Vicki, S. , DING, Li , THORNTON, Michael
IPC分类号: C12N15/53 , C12N15/55 , C12N9/16 , C12N9/20 , C12N9/02 , C12N15/63 , C12N1/21 , C12N5/10 , C12Q1/26 , C12N1/34 , C12Q1/68 , C07K16/40 , G01N33/53 , G01N33/68 , A61K38/44 , A61K38/46 , A61K39/395
CPC分类号: C12N9/0069 , A61K38/00 , C12N9/16 , C12N9/18 , C12N9/20
摘要: The invention provides human lipid metabolism enzymes (LME) and polynucleotides which identify and encode LME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LME.
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公开(公告)号:EP1487989A2
公开(公告)日:2004-12-22
申请号:EP02794113.7
申请日:2002-11-25
发明人: TANG, Y., Tom , CHAWLA, Narinder, K. , LU, Dyung Aina, M. , KHAN, Farrah, A. , GANDHI, Ameena, R. , SWARNAKAR, Anita , AZIMZAI, Yalda , MARQUIS, Joseph, P. , SPRAGUE, William, W. , EMERLING, Brooke, M. , YUE, Henry , BOROWSKY, Mark, L. , BECHA, Shanya, D. , ISON, Craig, H. , ELLIOTT, Vicki, S. , HAFALIA, April, J., A. , RING, Huijun, Z. , WARREN, Bridget, A. , GIETZEN, Kimberly, J. , TRAN, Uyen K. , LEE, Soo Yeun , LEE, Ernestine A. , RICHARDSON, Thomas W. , KABLE, Amy E. , BURFORD, Neil , LEHR-MASON, Patricia M. , GORVARD, Ann E. , LEE, Sally , BLAKE, Julie J. , HONCHELL, Cynthia D. , THANGAVELU, Kavitha , RAMKUMAR, Jayalaxmi , CHIEN, David , JIN, Pei , CHANG, Hsin-Ru , BAUGHN, Mariah R. , NGUYEN, Danniel B. , KHARE, Reena , BHATIA, Umesh , BURRILL, John D. , HO, Anne , ZHENG, Wenjin
CPC分类号: C07K14/47
摘要: Various embodiments of the invention provide human molecules for diseasedetection and treatment (MDDT) and polynucleotides which identify and encode MDDT. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.
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公开(公告)号:EP1423511A2
公开(公告)日:2004-06-02
申请号:EP02761367.8
申请日:2002-08-14
发明人: BARROSO, Ines , BAUGHN, Mariah, R. , BECHA, Shanya, D. , BLAKE, Julie, J. , BOROWSKY, Mark, L. , BURFORD, Neil , DUGGAN, Brendan, M. , ELLIOTT, Vicki, S. , EMERLING, Brooke, M. , FORSYTHE, Ian, J. , GIETZEN, Kimberly, J. , GORVAD, Ann, E. , GRIFFIN, Jennifer, A. , HAFALIA, April, J.A. , HONCHELL, Cynthia, D. , ISON, Craig, H. , KHAN, Farrah, A. , LAL, Preeti, G. , LEE, Ernestine, A. , LEE, Sally , LEE, Soo Yeun , LI, Joana X. , LU, Dyung Aina M. , LU, Yan , LEHR-MASON, Patricia M. , NGUYEN, Danniel B. , RAMKUMAR, Jayalaxmi , SPRAGUE, William W. , TANG, Y. Tom , THANGAVELU, Kavitha , THORNTON, Michael , TRAN, Uyen K. , CHAWLA, Narinder K. , WARREN, Bridget A. , XU, Yuming , YAO, Monique G. , YUE, Henry , YUE, Huibin , ZEBARJADIAN, Yeganeh
CPC分类号: C07K14/4702 , A61K38/00 , G01N2500/00
摘要: Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译: 本发明的各种实施方案提供了鉴定和编码NAAP的人核酸相关蛋白(NAAP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供了用于诊断,治疗或预防与NAAP的异常表达相关的病症的方法。
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10.
公开(公告)号:EP1404350A2
公开(公告)日:2004-04-07
申请号:EP02749588.6
申请日:2002-06-12
发明人: YUE, Henry , LU, Dyung Aina, M. , HAFALIA, April, J., A. , ARVIZU, Chandra, S. , RAMKUMAR, Jayalaxmi , TANG, Y., Tom , KHAN, Farrah, A. , BELL, Barrie, D. , RICHARDSON, Thomas, W. , YANG, Junming , ISON, Craig, H. , WARREN, Bridget, A. , ELLIOTT, Vicki, S. , EMERLING, Brooke, M. , GORVAD, Ann, E. , LEE, Ernestine, A. , GRIFFIN, Jennifer, A. , ZEBARJADIAN, Yeganeh , SWARNAKAR, Anita , BAUGHN, Mariah, R. , TRAN, Uyen, K.
IPC分类号: A61K35/00
CPC分类号: C07K14/4702 , A01K2217/05 , A61K38/00 , C07K14/4747
摘要: Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
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