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公开(公告)号：EP4233869A2
公开(公告)日：2023-08-30
申请号：EP23161858.8
申请日：2014-02-28
发明人： LI, Yun-Long , YAO, Wenqing , COMBS, Andrew P. , YUE, Eddy W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, JR., Thomas P. , SPARKS, Richard B. , DOUTY, Brent , HE, Chunhong
IPC分类号： A61K31/519 , A61K31/5377 , A61P35/00
摘要： The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I:
or pharmaceutically acceptable salts thereof.-
公开(公告)号：EP4233869A3
公开(公告)日：2023-11-01
申请号：EP23161858.8
申请日：2014-02-28
发明人： LI, Yun-Long , YAO, Wenqing , COMBS, Andrew P. , YUE, Eddy W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, JR., Thomas P. , SPARKS, Richard B. , DOUTY, Brent , HE, Chunhong
IPC分类号： A61K31/519 , A61K31/5377 , A61P35/00 , C07D487/04
摘要： The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I:
or pharmaceutically acceptable salts thereof.-
公开(公告)号：EP3513793A1
公开(公告)日：2019-07-24
申请号：EP18215449.2
申请日：2012-08-31
发明人： LI, Yun-Long , YAO, Wenqing , COMBS, Andrew, P. , YUE, Eddy, W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, Thomas, P., Jr. , SPARKS, Richard, B. , DOUTY, Brent , HE, Chunhong
摘要： The present invention provides heterocyclylamine derivatives of Formula I:
wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.-
公开(公告)号：EP3888657A1
公开(公告)日：2021-10-06
申请号：EP21158471.9
申请日：2012-08-31
发明人： LI, Yun-Long , YAO, Wenqing , COMBS, Andrew, P. , YUE, Eddy, W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, Thomas, P., Jr. , SPARKS, Richard, B. , DOUTY, Brent , HE, Chunhong
摘要： The present invention provides heterocyclylamine derivatives of Formula I:
wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.-
公开(公告)号：EP3632442A1
公开(公告)日：2020-04-08
申请号：EP19208523.1
申请日：2014-02-28
发明人： LI, Yun-Long , YAO, Wenqing , COMBS, Andrew P. , YUE, Eddy W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, JR., Thomas P. , SPARKS, Richard B. , DOUTY, Brent , HE, Chunhong
IPC分类号： A61K31/519 , A61K31/5377 , A61P35/00
摘要： The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I:
or pharmaceutically acceptable salts thereof.-
公开(公告)号：EP2961410B1
公开(公告)日：2019-12-11
申请号：EP14710739.5
申请日：2014-02-28
发明人： LI, Yun-Long , YAO, Wenqing , COMBS, Andrew P. , YUE, Eddy W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, JR., Thomas P. , SPARKS, Richard B. , DOUTY, Brent , HE, Chunhong
IPC分类号： A61K31/519 , A61K31/5377 , A61P35/00
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公开(公告)号：EP2751109B1
公开(公告)日：2016-11-30
申请号：EP12775861.3
申请日：2012-08-31
发明人： LI, Yun-Long , YAO, Wenqing , COMBS, Andrew, P. , YUE, Eddy, W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, Thomas, P., Jr. , SPARKS, Richard, B. , DOUTY, Brent , HE, Chunhong
IPC分类号： C07D471/04 , C07D487/04 , A61K31/519 , A61P35/00 , A61P29/00 , A61P27/00 , A61P19/00 , A61P1/00 , A61P17/00 , C07D519/00
CPC分类号： A61K31/519 , C07D471/04 , C07D487/04 , C07D519/00
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8.发明公开USE OF PYRAZOLOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PI3K RELATED DISORDERS 审中-公开PYRAZOLOPYRIMIDINDERIVATEN用于治疗PI3K相关疾病中的应用
公开(公告)号：EP2961410A1
公开(公告)日：2016-01-06
申请号：EP14710739.5
申请日：2014-02-28
发明人： LI, Yun-Long , YAO, Wenqing , COMBS, Andrew P. , YUE, Eddy W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, JR., Thomas P. , SPARKS, Richard B. , DOUTY, Brent , HE, Chunhong
IPC分类号： A61K31/519 , A61K31/5377 , A61P35/00
摘要： The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I: or pharmaceutically acceptable salts thereof.
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