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公开(公告)号:EP4233869A3
公开(公告)日:2023-11-01
申请号:EP23161858.8
申请日:2014-02-28
发明人: LI, Yun-Long , YAO, Wenqing , COMBS, Andrew P. , YUE, Eddy W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, JR., Thomas P. , SPARKS, Richard B. , DOUTY, Brent , HE, Chunhong
IPC分类号: A61K31/519 , A61K31/5377 , A61P35/00 , C07D487/04
摘要: The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I:
or pharmaceutically acceptable salts thereof.-
公开(公告)号:EP3019502A1
公开(公告)日:2016-05-18
申请号:EP14747194.0
申请日:2014-07-07
IPC分类号: C07D498/06 , A61K31/5383 , A61P35/00 , A61P31/00 , A61P29/00
CPC分类号: C07D498/06
摘要: The present invention relates to tricyclic heterocycles of Formula (I), which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer.
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公开(公告)号:EP3581576A1
公开(公告)日:2019-12-18
申请号:EP19189853.5
申请日:2014-03-14
IPC分类号: C07D498/06 , A61P35/00 , A61K31/5383
摘要: The present invention relates to tricyclic heterocycles which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer in combination with a Janus kinase inhibitor.
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4.USE OF PYRAZOLOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PI3K RELATED DISORDERS 审中-公开
标题翻译: PYRAZOLOPYRIMIDINDERIVATEN用于治疗PI3K相关疾病中的应用公开(公告)号:EP2961410A1
公开(公告)日:2016-01-06
申请号:EP14710739.5
申请日:2014-02-28
发明人: LI, Yun-Long , YAO, Wenqing , COMBS, Andrew P. , YUE, Eddy W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, JR., Thomas P. , SPARKS, Richard B. , DOUTY, Brent , HE, Chunhong
IPC分类号: A61K31/519 , A61K31/5377 , A61P35/00
摘要: The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I: or pharmaceutically acceptable salts thereof.
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公开(公告)号:EP4233869A2
公开(公告)日:2023-08-30
申请号:EP23161858.8
申请日:2014-02-28
发明人: LI, Yun-Long , YAO, Wenqing , COMBS, Andrew P. , YUE, Eddy W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, JR., Thomas P. , SPARKS, Richard B. , DOUTY, Brent , HE, Chunhong
IPC分类号: A61K31/519 , A61K31/5377 , A61P35/00
摘要: The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I:
or pharmaceutically acceptable salts thereof.-
公开(公告)号:EP3194406A1
公开(公告)日:2017-07-26
申请号:EP15771373.6
申请日:2015-09-14
IPC分类号: C07D498/06 , A61K31/5365 , A61P29/00 , A61P35/00 , A61P31/12
CPC分类号: C07D498/06
摘要: The present disclosure relates to tricyclic heterocycles which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer.
摘要翻译: 本公开涉及三环杂环,其为BET蛋白例如BRD2,BRD3,BRD4和BRD-t的抑制剂并且可用于治疗诸如癌症的疾病。
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公开(公告)号:EP3632442A1
公开(公告)日:2020-04-08
申请号:EP19208523.1
申请日:2014-02-28
发明人: LI, Yun-Long , YAO, Wenqing , COMBS, Andrew P. , YUE, Eddy W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, JR., Thomas P. , SPARKS, Richard B. , DOUTY, Brent , HE, Chunhong
IPC分类号: A61K31/519 , A61K31/5377 , A61P35/00
摘要: The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I:
or pharmaceutically acceptable salts thereof.-
公开(公告)号:EP2961410B1
公开(公告)日:2019-12-11
申请号:EP14710739.5
申请日:2014-02-28
发明人: LI, Yun-Long , YAO, Wenqing , COMBS, Andrew P. , YUE, Eddy W. , MEI, Song , ZHU, Wenyu , GLENN, Joseph , MADUSKUIE, JR., Thomas P. , SPARKS, Richard B. , DOUTY, Brent , HE, Chunhong
IPC分类号: A61K31/519 , A61K31/5377 , A61P35/00
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公开(公告)号:EP2970282B1
公开(公告)日:2019-08-21
申请号:EP14721642.8
申请日:2014-03-14
IPC分类号: C07D471/06 , C07D498/06 , A61K31/5383 , A61K31/437 , A61P35/00 , A61P29/00 , A61P31/00
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公开(公告)号:EP2064194B1
公开(公告)日:2018-11-07
申请号:EP07842681.4
申请日:2007-09-18
IPC分类号: C07D261/18 , C07D261/20 , C07D333/70 , C07D307/68 , A61K31/415 , A61K31/34 , A61K31/381 , A61P35/00 , A61P29/00 , A61P25/00 , A61P31/12
CPC分类号: C07D261/18 , C07D261/20 , C07D307/68 , C07D333/70
摘要: The present invention is directed to N-hydroxyamidino compounds which are modulators of indoleamine 2,3-dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof.
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