专利检索 ap:("Indiana University Research & Technology Corporation" OR "Assembly Biosciences, Inc.") AND inv:"TURNER, JR., William W." 第 1 页

1.

发明公开
HEPATITIS B VIRAL ASSEMBLY EFFECTORS 审中-公开
标题翻译：乙型肝炎病毒组装效果器

公开(公告)号：EP3283472A1

公开(公告)日：2018-02-21

申请号：EP16780846.8

申请日：2016-04-15

申请人： Indiana University Research & Technology Corporation , Assembly Biosciences, Inc.

发明人： ARNOLD, Lee Daniel , MAAG, Hans , TURNER, JR., William W.

IPC分类号： C07D401/04 , A01N43/54

CPC分类号： C07D403/14 , A61K31/496 , A61K31/506 , A61P31/20 , C07D213/74 , C07D239/42 , C07D239/47 , C07D239/48 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D409/12 , C07D413/04 , C07D417/04 , C07D417/12 , C07D417/14

摘要： Novel assembly effector compounds having a therapeutic effect against hepatitis B viral (HBV) infection are disclosed. Assembly effector molecules described herein can lead to defective viral assembly and also may affect other viral activities associated with chronic HBV infection. Also disclosed is a process to synthesize disclosed compounds, method of treatment of HBV by administration of disclosed compounds, and use of these compounds in the manufacture of medicaments against HBV.