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26 条记录 (耗时 0.021 秒)

    COMPOSITION FOR PREVENTING OR TREATING OBESITY-RELATED DISEASES MEDIATED BY THE ACTIVATION OF AMPK AND INCLUDING 2,5-BIS-ARYL-3,4-DIMETHYLTETRAHYDROFURAN LIGNANS AS ACTIVE INGREDIENTS
    2.
    发明公开
    COMPOSITION FOR PREVENTING OR TREATING OBESITY-RELATED DISEASES MEDIATED BY THE ACTIVATION OF AMPK AND INCLUDING 2,5-BIS-ARYL-3,4-DIMETHYLTETRAHYDROFURAN LIGNANS AS ACTIVE INGREDIENTS 有权
    组成预防和FETTLEIBIGKEITSBEDINGTEN BY AMPK激活疾病的治疗及2,5-二芳基-3,4- DIMETHYLTETRAHYDROFURANLIGNANEN为活动

    公开(公告)号：EP2438923A1

    公开(公告)日：2012-04-11

    申请号：EP09845576.9

    申请日：2009-06-26

    申请人： Industry-academic Cooperation Foundation, Chosun University ,  Amorepacific Corporation

    发明人： OH, Won Keun ,  NGUYEN, Phi Hung ,  LE, Thi Van Thu ,  KANG, Hu Won ,  SHIN, Eui Seok ,  CHIO, Jin Kyu ,  SEO, Dae Bang ,  LEE, Sang Jun

    IPC分类号： A61K36/185

    CPC分类号： A61K36/185 ,  A61K31/341 ,  A61K2236/333

    摘要： The present invention relates to a 2,5-bis-aryl-3,4-dimethyltetrahydrofuran lignan compound which activates nutmeg-derived AMP-activated protein kinase (AMPK), and to a composition including same as active ingredients for preventing and treating metabolic syndromes such as obesity. More particularly, the present invention relates to an AMPK-activating compound comprising one of the 2,5-bis-aryl-3,4-dimethyltetrahydrofuran lignan-based compounds produced by extracting Myristica fragrans with a solution of 30% or less of ethanol and separating and purifying the extracts using chromatography, as expressed in chemical formula 1 below, and to a composition comprising same as an active ingredient for preventing and treating metabolic syndrome caused by AMPK enzyme activation, such as obesity, diabetes, high cholesterol and cardiopulmonary diseases.

    摘要翻译： 本发明涉及一种2,5-二芳基-3,4-二甲基四氢呋喃木酚素类化合物哪激活肉豆蔻衍生AMP活化蛋白激酶（AMPK），并包括一种组合物一样用于预防和治疗代谢综合症的活性成分 ：如肥胖。 更具体地，本发明涉及包含通过以30％或和的溶液少的乙醇提取肉豆蔻产生的2,5-二芳基-3,4-二甲基四氢呋喃基于木脂素化合物中的一种AMPK活化化合物 分离并用色谱法纯化该提取物，如过表达在下面的化学式1，和一种组合物，其包括相同的用于预防和治疗由AMPK酶活化，：如肥胖，糖尿病，高血脂和心肺疾病引起代谢综合征的活性成分。

    COMPOSITION FOR PREVENTING OR TREATING ARTHEROSCLEROSIS
    8.
    发明公开
    COMPOSITION FOR PREVENTING OR TREATING ARTHEROSCLEROSIS 有权
    ZUSAMMENSETZUNG ZUR PREVENTION ODER BEHANDLUNG VON ATHEROSKLEROSE

    公开(公告)号：EP2368559A2

    公开(公告)日：2011-09-28

    申请号：EP09829329.3

    申请日：2009-11-26

    申请人： Amorepacific Corporation

    发明人： PARK, Chan-Woong ,  SEO, Dae Bang ,  JEON, Hee Young ,  LEE, Sang Min ,  KIM, Wan Gi ,  LEE, Sang Jun ,  KIM, Young-Myeong ,  KIM, Chun-Ki

    IPC分类号： A61K35/00 ,  A61P9/10 ,  A61K36/258 ,  A61K31/704 ,  A61K31/70

    CPC分类号： A61K36/258

    摘要： A composition according to the present invention is a composition containing extract of Panax ginseng C.A. Meyer fruit as an active ingredient for preventing or treating artherosclerosis. The extract is confirmed to effectively suppress lesions or generation of a vascular inflammation factor caused by artherosclerosis. Thus, the composition is suitable for use as an active ingredient of the composition for preventing or treating artherosclerosis.

    摘要翻译： 根据本发明的组合物是含有人参C.A.的提取物的组合物。 梅耶果作为预防或治疗动脉粥样硬化的有效成分。 证实提取物有效地抑制由动脉粥样硬化引起的损伤或血管炎症因子的产生。 因此，该组合物适合用作预防或治疗动脉粥样硬化的组合物的活性成分。

    USE FOR TREATING OBESITY AND DIABETES
    10.
    发明公开
    USE FOR TREATING OBESITY AND DIABETES 有权
    用于治疗肥胖和糖尿病

    公开(公告)号：EP2086532A1

    公开(公告)日：2009-08-12

    申请号：EP07793743.1

    申请日：2007-08-29

    申请人： Amorepacific Corporation

    发明人： PARK, Hyun Woo ,  CHUN, Ji Young ,  SHIN, Eui Seok ,  KIM, Yoo ,  LEE, Tae Ryong ,  LEE, Sang Jun

    IPC分类号： A61K31/35

    CPC分类号： A61K31/198 ,  A61K31/205 ,  A61K31/35 ,  A61K2300/00

    摘要： Disclosed herein is the use of a composition, containing isoflavone- containing soybean extract, L-carnitine, caffeine and arginine as active ingredients, for the treatment of obesity and diabetes. The disclosed composition contains isoflavone -containing soybean extract, carnitine, caffeine and arginine in the form of a mixture, and thus shows not only the effect of promoting lipolysis and fat burning, but also anti-obesity and anti-diabetic effects by increasing the expressions of adiponectin and Glut4 genes to restore insulin sensitivity.

    摘要翻译： 本文公开了含有含异黄酮的大豆提取物，L-肉碱，咖啡因和精氨酸作为活性成分的组合物用于治疗肥胖症和糖尿病的用途。 公开的组合物含有含异黄酮的大豆提取物，肉碱，咖啡因和精氨酸以混合物形式存在，因此不仅显示促进脂解和脂肪燃烧的效果，而且显示出通过增加表达 的脂联素和Glut4基因恢复胰岛素敏感性。