COMPOSITION FOR DETECTION OF SARS-COV-2 VIRUS GENE AND COVID-19 DIAGNOSISMETHOD USING REAL-TIME RT-PCR

    公开(公告)号:EP4056718A1

    公开(公告)日:2022-09-14

    申请号:EP22161710.3

    申请日:2022-03-11

    IPC分类号: C12Q1/70

    摘要: Disclosed herein are a composition for detection of a SARS-CoV-2 viral gene and COVID-19 diagnosis method using RT-PCR. More specifically, provided are a composition for detection of SARS-CoV-2 viral gene, a COVID-19 diagnosis kit comprising the composition, and a method for providing information for diagnosis of COVID-19, wherein the composition comprises: the primer of SEQ ID NO: 1, the primer of SEQ ID NO: 2, and the probe of SEQ ID NO: 3; or the primer of SEQ ID NO: 4, the primer of SEQ ID NO: 5, and the probe of SEQ ID NO: 6. Being able to specifically detect an RdRp or ORF3a gene of SARS-CoV-2 virus, with superiority to conventional detection methods in terms of detection specificity and sensitivity, the composition for detection of a SARS-CoV-2 viral gene and the diagnostic method for COVID-19 using same according to the present disclosure have the effect of promptly and accurately diagnosing COVID-19 through PCR in a simple manner.

    METHOD AND DEVICE FOR REDUCING AMOUNT OF CALCULATION FOR GENERATING HIERARCHICAL GALOIS KEY SET FOR HOMOMORPHIC ENCRYPTION ROTATION OPERATION

    公开(公告)号:EP4412143A1

    公开(公告)日:2024-08-07

    申请号:EP24154576.3

    申请日:2024-01-30

    IPC分类号: H04L9/00

    CPC分类号: H04L9/008

    摘要: A server for performing an operation on a homomorphic ciphertext according to an embodiment of the present disclosure may be configured to: receive a first homomorphic ciphertext, a public key, and a first hierarchical Galois key set from a client device; in response to a request for generating a second hierarchical Galois key set for performing a rotation operation on the first homomorphic ciphertext of the client device, generate the second hierarchical Galois key set, based on the received public key and hierarchical Galois key set; and when a decomposition operation for a first Galois key included in the second hierarchical Galois key set overlaps with a decomposition operation for a second Galois key, first perform the decomposition operation for the first Galois key, and then substitute the decomposition operation for the second Galois key with a result of the decomposition operation for the first Galois key. In addition, the second hierarchical Galois key set may be sequentially generated according to a predetermined generation order.

    USE OF P44 AS MARKER FOR DIAGNOSING ANAPLASMOSIS

    公开(公告)号:EP3967776A1

    公开(公告)日:2022-03-16

    申请号:EP20795112.0

    申请日:2020-04-21

    发明人: KIM, Dong Min

    IPC分类号: C12Q1/6883 G01N33/569

    摘要: A novel use of P 44 as a marker for predicting or diagnosing anaplasmosis is disclosed. A diagnostic composition for anaplasmosis containing a P 44 gene, a primer set or probe for detecting Anaplasma phagocytophilum, a kit for diagnosing anaplasmosis, and a method for providing information to diagnose infection with Anaplasma phagocytophilum are also disclosed. P 44 , which is a novel biomarker for diagnosing anaplasmosis, is a multi-copy gene and exists in a large number of copies in the Anaplasma phagocytophilum genome, thus having the effect of detecting Anaplasma phagocytophilum infection at high sensitivity using only a small amount of DNA compared to conventional diagnostic marker genes. In addition, the primer set or probe for detecting and amplifying P 44 is capable of providing rapid and easy detection of anaplasmosis with high specificity and sensitivity, making it appropriate for early detection of anaplasmosis.