专利检索 ap:("Innogenetics N.V." OR "INSERM (Institut National de la Santé et de la Recherche Médicale)" OR "Sanofi-Aventis" OR "Innogenetics N.V.") AND inv:"GOMPEL, Marie" 第 1 页

1.

发明公开
NEW ANTIBODIES SPECIFIC OF THE -AMYLOID PEPTIDES AND THEIR USES AS DIAGNOSTIC AGENTS OR DRUGS 审中-公开
标题翻译：新的β-淀粉样肽特异性抗体及其作为诊断剂或药物

公开(公告)号：EP2205633A1

公开(公告)日：2010-07-14

申请号：EP08844119.1

申请日：2008-10-24

申请人： Innogenetics N.V. , INSERM (Institut National de la Santé et de la Recherche Médicale) , Sanofi-Aventis , Innogenetics N.V.

发明人： VANMECHELEN, Eugeen , GROGNET, Pierre , SERGEANT, Nicolas , GOMPEL, Marie , DELACOURTE, André , BUEE, Luc , PRADIER, Laurent , BLANCHARD-BREGEON, Véronique

IPC分类号： C07K16/18 , A61K39/395 , G01N33/577 , C12N5/18 , C07K14/47 , A61P25/28

CPC分类号： C07K16/18 , A61K2039/505 , C07K14/4711 , C07K2317/56 , C07K2317/565 , C07K2317/92

摘要： The present invention relates to a monoclonal antibody which specifically binds to the N-terminal region of Aβ8-X peptide, x being comprised from 11 to 42, and recognises neither Aβ1-40 nor Aβ1-42 and which presents a high affinity with respect to Aβ8-X peptide, such as determined by an immunological complex formation between the monoclonal antibody and the peptide Aβ8-X.