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1.发明公开NEW ANTIBODIES SPECIFIC OF THE -AMYLOID PEPTIDES AND THEIR USES AS DIAGNOSTIC AGENTS OR DRUGS 审中-公开新的β-淀粉样肽特异性抗体及其作为诊断剂或药物
公开(公告)号：EP2205633A1
公开(公告)日：2010-07-14
申请号：EP08844119.1
申请日：2008-10-24
申请人： Innogenetics N.V. , INSERM (Institut National de la Santé et de la Recherche Médicale) , Sanofi-Aventis , Innogenetics N.V.
发明人： VANMECHELEN, Eugeen , GROGNET, Pierre , SERGEANT, Nicolas , GOMPEL, Marie , DELACOURTE, André , BUEE, Luc , PRADIER, Laurent , BLANCHARD-BREGEON, Véronique
IPC分类号： C07K16/18 , A61K39/395 , G01N33/577 , C12N5/18 , C07K14/47 , A61P25/28
CPC分类号： C07K16/18 , A61K2039/505 , C07K14/4711 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： The present invention relates to a monoclonal antibody which specifically binds to the N-terminal region of Aβ8-X peptide, x being comprised from 11 to 42, and recognises neither Aβ1-40 nor Aβ1-42 and which presents a high affinity with respect to Aβ8-X peptide, such as determined by an immunological complex formation between the monoclonal antibody and the peptide Aβ8-X.
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2.发明授权PHARMACEUTICAL COMPOSITION COMPRISING DESPRO36 EXENDIN-4(1-39)-LYS6 -NH2 FOR USE IN THE TREATMENT OF A NEURODEGENERATIVE DISEASE 有权药物组合物含DESPRO36艾塞那肽-4（1-39）-NH 2 -LYS6 FOR USE IN的神经变性疾病的治疗
公开(公告)号：EP2750698B1
公开(公告)日：2016-04-20
申请号：EP12755853.4
申请日：2012-09-03
发明人： HESS, Sibylle , HÖLSCHER, Christian , BÖHME, Andrees , MENUT, Agnes , PRADIER, Laurent , TAUPIN, Véronique
CPC分类号： A61K38/2278 , A61K38/26
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3.发明公开PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OF A NEURODEGENERATIVE DISEASE 有权药物组合物含DESPRO36艾塞那肽-4（1-39）-NH 2 -LYS6 FOR USE IN的神经变性疾病的治疗
公开(公告)号：EP2750698A1
公开(公告)日：2014-07-09
申请号：EP12755853.4
申请日：2012-09-03
发明人： HESS, Sibylle , HÖLSCHER, Christian , BÖHME, Andrees , MENUT, Agnes , PRADIER, Laurent , TAUPIN, Véronique
CPC分类号： A61K38/2278 , A61K38/26
摘要： The present invention refers to a pharmaceutical composition for use in the treatment of a neurodegenerative disease.
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