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公开(公告)号:EP3186370B1
公开(公告)日:2020-01-01
申请号:EP15780935.1
申请日:2015-08-27
申请人: Instytut Biochemii I Biofizyki Polskiej Akademii Nauk , Instytut Immunologii i Terapii Doswiadczalnej Polskiej Akademii Nauk
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2.ENZYME WITH HIGH LYTIC ACTIVITY AGAINST ENTEROCOCCUS CELL AND A METHOD OF MODIFICATION OF THE GENE THEREOF, ENABLING OVERPRODUCTION OF ACTIVE ENZYME IN BACTERIAL CELLS 审中-公开
标题翻译: 具有高活性的酶对肠球菌细胞的修饰及其基因修饰方法,使活性酶在细菌中过量生成公开(公告)号:EP3186370A1
公开(公告)日:2017-07-05
申请号:EP15780935.1
申请日:2015-08-27
申请人: Instytut Biochemii I Biofizyki Polskiej Akademii Nauk , Instytut Immunologii i Terapii Doswiadczalnej Polskiej Akademii Nauk
发明人: LOBOCKA, Malgorzata , GOZDEK, Agnieszka , KOSAKOWSKI, Jaroslaw , RÓZYCKA, Aleksandra , WEBER-DABROWSKA, Beata , GÓRSKI, Andrzej
摘要: Disclosed is an enzyme with high lytic activity against Enterococcus cells and a method of modification of the gene thereof, enabling overproduction of active enzyme in bacterial cells.
摘要翻译: 公开了一种对肠球菌细胞具有高溶解活性的酶及其基因的修饰方法,其能够在细菌细胞中过量生产活性酶。
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公开(公告)号:EP3186362B1
公开(公告)日:2019-05-15
申请号:EP15797403.1
申请日:2015-08-31
申请人: Instytut Biochemii I Biofizyki Polskiej Akademii Nauk , Instytut Immunologii I Terapii Doswiadczalnej Polskiej Akademii
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4.STAPHYLOCOCCUS AUREUS STRAINS FOR PRODUCTION OF MONOCLONAL PHAGE PREPARATIONS DEPRIVED OF CONTAMINATION WITH PLASMID DNA 审中-公开
标题翻译: 用于制备用质粒DNA污染的单克隆制备物的金黄色葡萄球菌菌株公开(公告)号:EP3186362A1
公开(公告)日:2017-07-05
申请号:EP15797403.1
申请日:2015-08-31
申请人: Instytut Biochemii I Biofizyki Polskiej Akademii Nauk , Instytut Immunologii I Terapii Do Wiadczalnej Polskiej Akademii Nauk
发明人: LOBOCKA, Malgorzata , HEJNOWICZ, Monika , DABROWSKI, Kamil , IZAK, Dariusz , GOZDEK, Agnieszka , GLOWACKA, Aleksandra , GAWOR, Jan , KOSAKOWSKI, Jaroslaw , GROMADKA, Robert , WEBER-DABROWSKA, Beata , GÓRSKI, Andrzej
CPC分类号: C12R1/445 , C12N1/20 , C12N7/00 , C12N2795/00051
摘要: Disclosed are Staphylococcus aureus strains for obtaining monoclonal preparations of lytic bacteriophages with high titer, devoid of contamination with undesired bacteriophages and plasmid DNA, which guarantee the production of safe to use bacteriophage preparations, not being a source of dissemination of genes associated with bacterial virulence.
摘要翻译: 公开了金黄色葡萄球菌菌株用于获得高滴度的溶解性噬菌体的单克隆制备物,其不含不希望的噬菌体和质粒DNA的污染,其保证产生安全使用的噬菌体制剂,而不是与细菌毒力相关的基因传播的来源。
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