公开(公告)号：EP1924594A2

公开(公告)日：2008-05-28

申请号：EP06800088.4

申请日：2006-07-17

申请人： Intermune, Inc. ,  Array Biopharma, Inc.

发明人： SEIWERT, Scott D. ,  BLATT, Lawrence M. ,  ANDREWS, Steven W. ,  MARTIN, Pierre ,  SCHUMACHER, Andreas ,  BARNETT, Bradley R. ,  EARY, C., Todd ,  KAUS, Robert ,  KERCHER, Timothy ,  LIU, Weidong ,  LYON, Michael ,  NICHOLS, Paul ,  WANG, Bin ,  SAMMAKIA, Tarek ,  KENNEDY, April ,  JIANG, Yutong

IPC分类号： C07K5/12 ,  A61K38/00 ,  A61P31/14 ,  C07D209/44 ,  C07C231/02 ,  C07C269/00 ,  C07D207/16

CPC分类号： C07K5/0806 ,  A61K38/00 ,  A61K38/1793 ,  A61K38/212 ,  A61K38/217 ,  A61K38/2292 ,  A61K38/55 ,  C07D471/04 ,  C07D487/04 ,  C07K5/0804 ,  A61K2300/00

摘要： The embodiments provide compounds of the general Formulae (I) through general Formula (VIII), as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.