专利检索 ap:("JANSSEN Pharmaceutica NV") AND inv:"TICHENOR, Mark S." 第 1 页

1.

发明公开
POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE 审中-公开

公开(公告)号：EP3719022A1

公开(公告)日：2020-10-07

申请号：EP20177012.0

申请日：2016-12-09

申请人： Janssen Pharmaceutica NV

发明人： ARORA, Nidhi , BACANI, Genesis M. , BARBAY, Joseph Kent , BEMBENEK, Scott D. , CAI, Min , CHEN, Wei , DECKHUT, Charlotte Pooley , EDWARDS, James P. , GHOSH, Brahmananda , KREUTTER, Kevin , LI, Gang , TICHENOR, Mark S. , VENABLE, Jennifer D. , WEI, Jianmei , WIENER, John J. M. , WU, Yao , XIAO, Kun , ZHANG, Feihuang , ZHU, Yaoping

IPC分类号： C07D495/16 , C07D519/00 , A61K31/519 , A61P35/00 , A61P37/00 , A61P19/00

摘要： The present disclosure is directed to compounds of Formula (I) as Bruton's kinase inhibitors and their preparation, as well as compositions comprising compounds of Formula (I).

2.

发明公开
INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE 审中-实审

公开(公告)号：EP4346834A1

公开(公告)日：2024-04-10

申请号：EP22733732.6

申请日：2022-06-02

申请人： Janssen Pharmaceutica NV

发明人： BALASUBRAMANIAN, Sriram , CORNELISSEN, Ivo , GUO, Yue , LEU, Jocelyn H. , PACKMAN, Kathryn E. , PALMER, James Alexander , PHILIPPAR, Ulrike , RAO, Navin , TICHENOR, Mark S. , VENABLE, Jennifer D. , WIENER, John J.M. , MIAO, Xin

IPC分类号： A61K31/519 , A61K31/635 , A61K9/00 , A61P35/00

3.

发明公开
CRYSTAL STRUCTURE OF BTK PROTEIN AND BINDING POCKETS THEREOF 审中-公开

公开(公告)号：EP4444428A1

公开(公告)日：2024-10-16

申请号：EP22835576.4

申请日：2022-12-07

申请人： JANSSEN Pharmaceutica NV

发明人： ALEXANDER, Richard S. , MILLIGAN, Cynthia , TICHENOR, Mark S.

IPC分类号： A61P35/00 , A61K31/415 , C12N9/12 , G16B15/30

4.

发明公开
POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE 审中-公开

公开(公告)号：EP3386991A1

公开(公告)日：2018-10-17

申请号：EP16820106.9

申请日：2016-12-09

申请人： Janssen Pharmaceutica NV

发明人： ARORA, Nidhi , BACANI, Genesis M. , BARBAY, Joseph Kent , BEMBENEK, Scott D. , CAI, Min , CHEN, Wei , DECKHUT, Charlotte Pooley , EDWARDS, James P. , GHOSH, Brahmananda , KREUTTER, Kevin , LI, Gang , TICHENOR, Mark S. , VENABLE, Jennifer D. , WEI, Jianmei , WIENER, John J. M. , WU, Yao , XIAO, Kun , ZHANG, Feihuang , ZHU, Yaoping

IPC分类号： C07D495/16 , C07D519/00 , A61K31/519 , A61P35/00 , A61P37/00 , A61P19/00

摘要： The present disclosure is directed to compounds of Formula (I) as Bruton's kinase inhibitors and their preparation, as well as compositions comprising compounds of Formula (I).

5.

发明公开
INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE 审中-实审

公开(公告)号：EP4362947A1

公开(公告)日：2024-05-08

申请号：EP22741472.9

申请日：2022-06-29

申请人： Janssen Pharmaceutica NV

发明人： BUSSOLARI, Jacqueline Cirillo , PHILIPPAR, Ulrike , STEELE, Andrew , TICHENOR, Mark S.

IPC分类号： A61K31/519 , A61P35/00 , A61K45/00 , A61K31/675 , A61K31/704

CPC分类号： A61K31/519 , A61P35/00 , A61K45/00 , A61K31/675 , A61K31/704

6.

发明公开
SMALL MOLECULE INHIBITORS OF THE JAK FAMILY OF KINASES 审中-公开

公开(公告)号：EP3807277A1

公开(公告)日：2021-04-21

申请号：EP19759032.6

申请日：2019-06-14

申请人： Janssen Pharmaceutica NV

发明人： FERNANDES, Philippe , TICHENOR, Mark S. , KRAWCZUK, Paul J.

IPC分类号： C07D471/14

7.

发明授权
POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE 有权

公开(公告)号：EP3386991B1

公开(公告)日：2020-06-03

申请号：EP16820106.9

申请日：2016-12-09

申请人： Janssen Pharmaceutica NV

发明人： ARORA, Nidhi , BACANI, Genesis M. , BARBAY, Joseph Kent , BEMBENEK, Scott D. , CAI, Min , CHEN, Wei , DECKHUT, Charlotte Pooley , EDWARDS, James P. , GHOSH, Brahmananda , KREUTTER, Kevin , LI, Gang , TICHENOR, Mark S. , VENABLE, Jennifer D. , WEI, Jianmei , WIENER, John J. M. , WU, Yao , XIAO, Kun , ZHANG, Feihuang , ZHU, Yaoping

IPC分类号： C07D495/16 , C07D519/00 , A61K31/519 , A61P35/00 , A61P37/00 , A61P19/00