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1.PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV 审中-公开
标题翻译: 制备HCV的大环蛋白酶抑制剂的过程和中间体公开(公告)号:EP3274324A1
公开(公告)日:2018-01-31
申请号:EP16715347.7
申请日:2016-03-25
发明人: DEPRÉ, Dominique Paul Michel , ORMEROD, Dominic John , HORVATH, Andras , MOODY, Thomas Shaw , BROSSAT, Maude , RIANT, Olivier , VRIAMONT, Nicolas , LEMAIRE, Sébastien François Emmanuel , HERMANT, Sébastien Nicolas J.
IPC分类号: C07C67/08 , C07C67/30 , C07C67/31 , C07C67/60 , C07D417/04 , C07D417/14 , C07C231/02 , C07C231/12
CPC分类号: C07C235/82 , C07B2200/07 , C07C67/31 , C07C69/757 , C07C231/02 , C07C231/12 , C07C233/60 , C07C233/61 , C07C2601/08 , C07D417/04 , C07D417/14 , C12P41/001
摘要: Disclosed is a process for the preparation of certain intermediates, e.g. those in the scheme below: which intermediates and processes are useful in the preparation of the macrocyclic HVC inhibitor Simeprevir.