公开(公告)号：EP1213348A2

公开(公告)日：2002-06-12

申请号：EP00112061.7

申请日：1986-03-17

申请人： Johnston, Stephen, Ph.D. ,  CORNELL RESEARCH FOUNDATION, INC.

发明人： Johnston, Stephen A., University of Texas ,  Sanford, John C.

IPC分类号： C12N15/00 ,  C12N5/10 ,  C12N1/21 ,  C12N15/33 ,  C12N15/63 ,  C12N15/70 ,  C12N15/82

CPC分类号： C12N15/113 ,  A01K2217/05 ,  A01K2267/02 ,  A61K38/00 ,  A61K48/00 ,  C07K14/005 ,  C12N15/8509 ,  C12N15/87 ,  C12N2310/111 ,  C12N2510/00 ,  C12N2795/18122 ,  C12N2795/18143

摘要： There is described a method for conferring resistance to a parasite to a host of the parasite, as well as the hosts produced by this process, which comprises isolating a gene fragment from the parasite and inserting the gene fragment, or a DNA or RNA segment substantially homologous to at least a part of the gene fragment or to a DNA or RNA sequence functionally equivalent to the gene fragment, into the host, wherein the gene fragment, or the DNA or RNA segment inserted in the host, acts as a binding site competing with a native binding site in the parasite genome.