-
1.发明公开Plasmids containing a chicken beta-actin promoter and a human factor VIII:C gene, transformants and processes for preparing human factor VIII:C 失效鸡β-肌动蛋白启动子和人因子VIII-C含基因的质粒，转化体和方法用于生产人因子VIII-C的。
公开(公告)号：EP0351586A1
公开(公告)日：1990-01-24
申请号：EP89111482.9
申请日：1989-06-23
发明人： Yonemura, Hiroshi , Sugiyama, Takashi c/o Biomedical Institute , Araki, Masatake , Nozaki, Chikateru , Miyazaki, Junichi Higashimachi , Yamamura, Ken-ichi Higashimachi
CPC分类号： C07K14/755 , C12N15/85
摘要： A plasmid for the expression of a protein having the biological activity of human factor VIII:C is described, which comprises a chicken β-actin promoter or a derivative thereof and downstream of the promoter a gene coding for said protein having the biological activity of human factor VIII:C. Furthermore, the corresponding transformed microoganisms and processes for the production of a protein having the biological activity of human VIII:C are described. The plasmids allow the production of protein having the biological activity of human factor VIII:C with a high efficiency in an industrial scale.
摘要翻译： 一种用于在具有人因子VIII的生物活性的蛋白质的表达质粒：C中描述，其包含鸡β-肌动蛋白启动子或其衍生物和下游的启动子的基因，其编码所述蛋白具有人的生物活性 因子VIII：C。 进一步，用于制备具有人VIII的生物活性的蛋白质的相应的变换微生物使和过程：C进行说明。 质粒允许生产具有人因子VIII的生物活性蛋白的：C与在工业规模上以高效率。
-
2.发明公开Vector containing a chicken beta-actin gene promoter for the expression of a desired gene 失效Hühner-beta-Actin-Genpromoter enthaltender Vektor zur Expression eineserwünschtenGens。
公开(公告)号：EP0351585A2
公开(公告)日：1990-01-24
申请号：EP89111481.1
申请日：1989-06-23
发明人： Miyazaki, Junichi Higashimachi , Yamamura, Ken-ichi Higashimachi , Araki, Masatake , Yonemura, Hiroshi , Nozaki, Chikateru
CPC分类号： C07K14/005 , C12N9/2471 , C12N15/85 , C12N2730/10122 , C12N2800/108 , C12N2830/00 , C12N2830/005 , C12N2830/15 , C12N2830/60 , C12N2830/90 , C12N2840/44 , C12Y302/01023
摘要： An expression vector for the expression of a desired gene in an animal cell is described, which contains a chicken β-actin gene promoter or a derivative thereof and downstream thereof a restriction enzyme site for the incorporation of a desired gene. Furthermore corresponding recombinant expression vectors, transformed microorganisms and processes for the expression of a desired gene in a host cell are described.
摘要翻译： 描述了用于在动物细胞中表达所需基因的表达载体，其含有鸡β-肌动蛋白基因启动子或其衍生物，并且其下游包含用于引入所需基因的限制酶位点。 此外，描述了相应的重组表达载体，转化的微生物和在宿主细胞中表达所需基因的方法。
-
3.发明公开Vector containing a chicken beta-actin gene promoter for the expression of a desired gene 失效含有用于表达所需基因的鸡B-ACTIN基因启动子的载体
公开(公告)号：EP0351585A3
公开(公告)日：1990-05-09
申请号：EP89111481.1
申请日：1989-06-23
发明人： Miyazaki, Junichi Higashimachi , Yamamura, Ken-ichi Higashimachi , Araki, Masatake , Yonemura, Hiroshi , Nozaki, Chikateru
CPC分类号： C07K14/005 , C12N9/2471 , C12N15/85 , C12N2730/10122 , C12N2800/108 , C12N2830/00 , C12N2830/005 , C12N2830/15 , C12N2830/60 , C12N2830/90 , C12N2840/44 , C12Y302/01023
摘要： An expression vector for the expression of a desired gene in an animal cell is described, which contains a chicken β-actin gene promoter or a derivative thereof and downstream thereof a restriction enzyme site for the incorporation of a desired gene. Furthermore corresponding recombinant expression vectors, transformed microorganisms and processes for the expression of a desired gene in a host cell are described.
-
4.发明授权Plasmids containing a chicken beta-actin promoter and a human factor VIII:C gene, transformants and processes for preparing human factor VIII:C 失效鸡β-肌动蛋白启动子和人因子VIII-C含基因的质粒，转化体和方法用于生产人因子VIII-C的。
公开(公告)号：EP0351586B1
公开(公告)日：1995-01-18
申请号：EP89111482.9
申请日：1989-06-23
发明人： Yonemura, Hiroshi , Sugiyama, Takashi c/o Biomedical Institute , Araki, Masatake , Nozaki, Chikateru , Miyazaki, Junichi Higashimachi , Yamamura, Ken-ichi Higashimachi
CPC分类号： C07K14/755 , C12N15/85
-
5.发明授权Vector containing a chicken beta-actin gene promoter for the expression of a desired gene 失效含有所希望的基因的表达载体的鸡β-肌动蛋白基因启动子。
公开(公告)号：EP0351585B1
公开(公告)日：1994-11-02
申请号：EP89111481.1
申请日：1989-06-23
发明人： Miyazaki, Junichi Higashimachi , Yamamura, Ken-ichi Higashimachi , Araki, Masatake , Yonemura, Hiroshi , Nozaki, Chikateru
CPC分类号： C07K14/005 , C12N9/2471 , C12N15/85 , C12N2730/10122 , C12N2800/108 , C12N2830/00 , C12N2830/005 , C12N2830/15 , C12N2830/60 , C12N2830/90 , C12N2840/44 , C12Y302/01023
-
-
-
-
搜索结果
5 条记录 (耗时 0.011 秒)
