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公开(公告)号：EP0139216A2
公开(公告)日：1985-05-02
申请号：EP84110996.0
申请日：1984-09-14
CPC分类号： C07K14/005 , A61K38/00 , C12N15/70 , C12N2740/14022
摘要： Recombinant plasmids are constructed by inserting a DNA fragment coding for adult T cell leukemia virus antigen peptide into a vector DNA. Microorganisms are transformed with the recombinant plasmid and thereafter cultured to express the peptide. The adult T cell leukemia virus antigen peptide is useful for the detection and diagnosis of adult T cell leukemia.
摘要翻译： 通过将编码成人T细胞白血病病毒抗原肽的DNA片段插入载体DNA构建重组质粒。 用重组质粒转化微生物，然后培养以表达肽。 成人T细胞白血病病毒抗原肽可用于检测和诊断成人T细胞白血病。
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2.发明公开Novel DNA, cloned DNA, recombinant plasmid containing the DNA, microorganism containing the recombinant plasmid and process for their production 失效新型DNA，克隆DNA，包含DNA的重组质粒，含有重组质粒的微生物及其生产方法
公开(公告)号：EP0028033A3
公开(公告)日：1981-08-19
申请号：EP80106685
申请日：1980-10-30
CPC分类号： C07K14/565
摘要： The invention relates to a DNA which codes for a polypeptide with interferon activity, a cloned DNA showing complementarity to human interferon mRNA, a recombinant plasmid containing such DNA, a microorganism containig the recombinant plasmid and a process for producing said DNA, said cloned DNA, said recombinant plasmid and said microorganism.
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3.发明公开Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid 失效双链DNA，其编码具有人成纤维细胞干扰素的活性的多肽，克隆的DNA，含有该DNA和含有该重组质粒的微生物的重组质粒。
公开(公告)号：EP0028033A2
公开(公告)日：1981-05-06
申请号：EP80106685.3
申请日：1980-10-30
CPC分类号： C07K14/565
摘要： The invention relates to a DNA which codes for a polypeptide with interferon activity, a cloned DNA showing complementarity to human interferon mRNA, a recombinant plasmid containing such DNA, a microorganism containig the recombinant plasmid and a process for producing said DNA, said cloned DNA, said recombinant plasmid and said microorganism.
摘要翻译： 本发明涉及一种DNA，其编码与干扰素活性的多肽，表示互补人干扰素mRNA的克隆的DNA，重组质粒含有寻求DNA，含有用于产生所述DNA的重组质粒和处理的微生物，所述克隆的DNA， 所述重组质粒和所述微生物。
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公开(公告)号：EP0152076A3
公开(公告)日：1986-08-13
申请号：EP85101354
申请日：1985-02-08
IPC分类号： C12N15/00 , C12P21/02 , C07K15/00 , C12N01/20 , G01N33/535
CPC分类号： C07K14/005 , C07K2319/00 , C07K2319/40 , C07K2319/61 , C12N2740/14022 , Y10S530/806 , Y10S530/808 , Y10S530/82 , Y10S530/825
摘要： Recombinant plasmids are constructed by inserting a DNA fragment coding for a fused protein of an adult T cell leukemia virus antigen peptide and an enzyme into a vector DNA. Microorganisms are transformed with the recombinant . plasmid and thereafter cultured to express the fused protein. The fused protein is useful for the detection and diagnosis of adult T cell leukamia.
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5.发明公开Derivative of adult T cell leukemia virus antigen peptide 失效Derivat des Adult-T-Zell-Leukemiavirus-Antigenpeptids。
公开(公告)号：EP0152076A2
公开(公告)日：1985-08-21
申请号：EP85101354.0
申请日：1985-02-08
IPC分类号： C12N15/00 , C12P21/02 , C07K15/00 , C12N1/20 , G01N33/535
CPC分类号： C07K14/005 , C07K2319/00 , C07K2319/40 , C07K2319/61 , C12N2740/14022 , Y10S530/806 , Y10S530/808 , Y10S530/82 , Y10S530/825
摘要： Recombinant plasmids are constructed by inserting a DNA fragment coding for a fused protein of an adult T cell leukemia virus antigen peptide and an enzyme into a vector DNA. Microorganisms are transformed with the recombinant . plasmid and thereafter cultured to express the fused protein. The fused protein is useful for the detection and diagnosis of adult T cell leukamia.
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公开(公告)号：EP0064681A2
公开(公告)日：1982-11-17
申请号：EP82103678.7
申请日：1982-04-29
CPC分类号： C07K14/565 , C12N15/70
摘要： Disclosed is a novel recombinant DNA containing the tufB promoter of Escherichia coli and a gene coding for the biosynthesis of a eukaryotic protein such as human interferon β 1 . Also disclosed is a process for producing a eukaryotic protein by culturing a microorganism carrying a plasmid containing the tufB promoter and a gene coding for such protein.
摘要翻译： 公开了含有大肠杆菌的tufB启动子和编码人干扰素β1等真核生物合成的基因的新型重组DNA。还公开了一种通过培养携带含有 tufB启动子和编码这种蛋白质的基因。
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公开(公告)号：EP0152076B1
公开(公告)日：1990-05-16
申请号：EP85101354.0
申请日：1985-02-08
IPC分类号： C12N15/00 , C12P21/02 , C07K15/00 , C12N1/20 , G01N33/535
CPC分类号： C07K14/005 , C07K2319/00 , C07K2319/40 , C07K2319/61 , C12N2740/14022 , Y10S530/806 , Y10S530/808 , Y10S530/82 , Y10S530/825
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公开(公告)号：EP0152030A3
公开(公告)日：1986-08-13
申请号：EP85101063
申请日：1985-02-01
IPC分类号： C12N15/00 , C12P21/02 , C12N01/18 , C07K15/00 , C12R01/865
CPC分类号： C07K14/005 , C12N15/81 , C12N2740/14022
摘要： Recombinant plasmids are constructed by inserting a DNA fragment containing the env gene of adult T cell leukemia virus into a vector DNA. Microorganisms are transformed with the recombinant plasmid and thereafter cultured to express the gene and to recover the peptide. The antigenic polypeptide encoded by the env gene is useful for detection and diagnosis of adult T cell leukemia.
摘要翻译： 通过将含有成人T细胞白血病病毒的env基因的DNA片段插入载体DNA构建重组质粒。 用重组质粒转化微生物，然后培养表达基因并回收肽。 由env基因编码的抗原性多肽可用于检测和诊断成人T细胞白血病。
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9.发明授权Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid 失效具有人纤维细胞干扰素活性的多肽的双链DNA，克隆的DNA，含有包含重组质粒的DNA和微生物的重组体PLASMID
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公开(公告)号：EP0121157A1
公开(公告)日：1984-10-10
申请号：EP84102712.1
申请日：1984-03-13
摘要： Disclosed is a novel human interferon-y polypeptide, a recombinant plasmid wherein a DNAfragment coding forthe polypeptide is incorporated, and a process for producing the human interferon-y polypeptide using a microorganism containing the plasmid.
摘要翻译： 公开了一种新型人类干扰素-γ多肽，其中掺入编码多肽的DNA片段的重组质粒，以及使用含有该质粒的微生物生产人类干扰素-γ多肽的方法。
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