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公开(公告)号:EP0196917A3
公开(公告)日:1988-01-13
申请号:EP86302416
申请日:1986-04-01
发明人: Tanaka, Ryuichiro , Takamizawa, Koutaro , Takayama, Hiroo , Sakurai, Toshizo , Mada, Mitsuo , Mutai, Masahiko
CPC分类号: C07H15/10 , A61K31/00 , A61K35/20 , Y02A50/469 , Y10S514/823
摘要: A botulinus toxin neutralizer comprises (a) heat-treated fat globule membranes of animal milk or (b) gangliosides isolated from fat globule membranes of animal milk. The neutralizer (a) can be prepared from a material containing fat globules of animal milk by fractionating the material to separate the membranes of the fat globules, and subjecting the separated fat globule membranes to heat treatment. The neutralizer (b) can be prepared from a material containing fat globules of animal milk by fractionating the material to separate tne membranes of the fat globules, and isolating gangliosides from the separated globule membranes.
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公开(公告)号:EP0196917A2
公开(公告)日:1986-10-08
申请号:EP86302416.2
申请日:1986-04-01
发明人: Tanaka, Ryuichiro , Takamizawa, Koutaro , Takayama, Hiroo , Sakurai, Toshizo , Mada, Mitsuo , Mutai, Masahiko
CPC分类号: C07H15/10 , A61K31/00 , A61K35/20 , Y02A50/469 , Y10S514/823
摘要: A botulinus toxin neutralizer comprises (a) heat-treated fat globule membranes of animal milk or (b) gangliosides isolated from fat globule membranes of animal milk. The neutralizer (a) can be prepared from a material containing fat globules of animal milk by fractionating the material to separate the membranes of the fat globules, and subjecting the separated fat globule membranes to heat treatment. The neutralizer (b) can be prepared from a material containing fat globules of animal milk by fractionating the material to separate tne membranes of the fat globules, and isolating gangliosides from the separated globule membranes.
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公开(公告)号:EP0196917B1
公开(公告)日:1991-10-16
申请号:EP86302416.2
申请日:1986-04-01
发明人: Tanaka, Ryuichiro , Takamizawa, Koutaro , Takayama, Hiroo , Sakurai, Toshizo , Mada, Mitsuo , Mutai, Masahiko
CPC分类号: C07H15/10 , A61K31/00 , A61K35/20 , Y02A50/469 , Y10S514/823
摘要: A botulinus toxin neutralizer comprising heat-treated fat globule membranes of animal milk or gangliosides isolated from fat globule membranes of animal milk. The neutralizer of the former nature is prepared from a material containing fat globules of animal milk by fractionating the material for separating the membranes of the fat globules from the rest of the material, and subjecting the separated fat globule membranes to heat treatment. The neutralizer of the former nature is prepared from a material containing fat globules by fractionating the material for separating the membranes of the fat globules from the rest of the material, and isolating gangliosides from the globule membranes.
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