公开(公告)号：EP0657415A4

公开(公告)日：1995-08-23

申请号：EP94919815

申请日：1994-06-29

申请人： KANEKA CORP

发明人： MITSUDA MASARU ,  HAYASHI SHIGEO ,  HASEGAWA JUNZO ,  UEYAMA NOBORU ,  OHASHI TAKEHISA ,  SHIBASAKI MASAKATSU

IPC分类号： C07C213/02 ,  C07C215/28 ,  C07C227/02 ,  C07C229/34 ,  C07C269/02 ,  C07C271/16 ,  C07C213/00

CPC分类号： C07C269/02 ,  C07C213/02 ,  C07C215/28 ,  C07C227/02 ,  C07C229/34 ,  C07C271/16 ,  Y02P20/55

摘要： A process for producing a 3-amino-1-nitro-4-phenyl-2-butanol derivative represented by general formula (1) and a 3-amino-2-hydroxy-4-phenyl-butyric acid derivative derived therefrom. In said formula, R and R represent each independently hydrogen or an amino-protecting group. The process can industrially provide an optically active amino alcohol derivative as an intermediate for synthesizing medicines such as an immunopotentiating carcinostatic bestatin in a high yield safely, readily and highly selectively.