公开(公告)号：EP2035377A1

公开(公告)日：2009-03-18

申请号：EP07725521.4

申请日：2007-05-24

申请人： KARO BIO AB

发明人： GARCIA COLLAZO, Ana Maria ,  KOCH, Eva, Kristina ,  MALM, Lars, Johan ,  CHENG, Aiping ,  HANSSON, Tomas, Fredrik

IPC分类号： C07D209/08 ,  C07D209/18 ,  C07D209/20 ,  C07D405/04 ,  C07D413/04 ,  A61P5/14 ,  A61K31/404

CPC分类号： C07D209/08 ,  C07D209/10 ,  C07D209/12 ,  C07D209/42 ,  C07D401/04 ,  C07D405/04 ,  C07D413/04

摘要： The invention provides compounds of formula (I) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, (I) wherein R1, R2, R3, R4, R5, R6, Y and W are as defined in the specification. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition that may be treated with a thyroid receptor agonist or partial agonist.

公开(公告)号：EP2024336A1

公开(公告)日：2009-02-18

申请号：EP07724830.0

申请日：2007-05-03

申请人： KARO BIO AB

发明人： GARCIA COLLAZO, Ana Maria ,  KOCH, Eva, Kristina ,  LÖFSTEDT, Anton, Joakim ,  CHENG, Aiping ,  GORDON, Sandra ,  HANSSON, Tomas, Fredrik

IPC分类号： C07D235/06 ,  C07D235/08 ,  C07D235/10 ,  C07D235/14 ,  C07D235/18 ,  C07D235/24 ,  C07D235/28 ,  C07D235/30 ,  C07D403/04 ,  C07D407/04 ,  C07D413/04 ,  A61K31/4184 ,  A61K31/422 ,  A61P5/14

CPC分类号： C07D235/08 ,  C07D235/06 ,  C07D235/10 ,  C07D235/14 ,  C07D235/18 ,  C07D235/24 ,  C07D235/28 ,  C07D235/30 ,  C07D403/04 ,  C07D405/04 ,  C07D413/04

摘要： The invention provides the use of compounds of formula (I) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, for the manufacture of a medicament for the treatment or prophylaxis of a condition that may be treated with a thyroid receptor agonist or partial agonist wherein R1, R2, R3, R4, Y, W and R5 are as defined in the specification. The invention also provides compounds of formula (Ia) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, formula (Ia) wherein R1, R2, R3, R4, Y, W and R5 are as defined in the specification.