专利检索 ap:("KIRIN BEER KABUSHIKI KAISHA") AND inv:"DRMANAC, Radoje T." 第 1 页

1.

发明公开
POLYPEPTIDE HAVING AN ACTIVITY TO SUPPORT PROLIFERATION OR SURVIVAL OF HEMATOPOIETIC STEM CELL AND HEMATOPOIETIC PROGENITOR CELL, AND DNA CODING FOR THE SAME 审中-公开
标题翻译：多肽，其增殖或干细胞和造血造血祖细胞的支持者和编码DNA的存活

公开(公告)号：EP1395610A2

公开(公告)日：2004-03-10

申请号：EP02733478.8

申请日：2002-06-11

申请人： KIRIN BEER KABUSHIKI KAISHA

发明人： NISHIKAWA, Mitsuo,c/o Kirin Beer K. K. , DRMANAC, Radoje T. , LABAT, Ivan , LEE, Juhi , TANG, Y. Tom , STACHE-CRAIN, Birgit

IPC分类号： C07K14/475 , C12N15/12 , C12N5/06 , A61K38/00 , C07K16/22

CPC分类号： C12N5/0647 , A61K38/00 , C07K14/475

摘要： A gene encoding a polypeptide having an activity to support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is isolated by comparing expressed genes between cells which support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells and cells which do not support the proliferation or survival. Proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is supported by using stromal cells in which the isolated gene is expressed or a gene product of the isolated gene.