-
公开(公告)号：EP1740531A1
公开(公告)日：2007-01-10
申请号：EP05733398.1
申请日：2005-04-13
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY , Jeil Pharmaceutical Co., Ltd. , Korea Research Institute of Bioscience and Biotechnology , CJ Corp
发明人： CHEON, Hyae Gyeong , YOO, Sung-Eun , KIM, Sung Soo , YANG, Sung-Don , KIM, Kwang-Rok , RHEE, Sang Dal , AHN, Jin Hee , KANG, Seung Kyu , JUNG, Won Hoon , PARK, Sung Dae , KIM, Nam Gee , LEE, Jang Hyuk , HUH, Sun Chul , LEE, Jae Mok , SONG, Seog Beom , KWON, Soon Ji , KIM, Jong H. , LEE, Jeong-Hyung , KIM, Seung Jun
IPC分类号： C07C251/44
CPC分类号： C07D213/30 , C07C291/02 , C07C309/66 , C07C2601/02 , C07C2601/14 , C07C2602/08 , C07C2603/74 , C07D213/53 , C07D233/64 , C07D277/24 , C07D295/088 , C07D295/185 , C07D307/54 , C07D317/60 , C07D317/70 , C07D333/24 , C07D333/28 , C07D417/12
摘要： The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer.
摘要翻译： 式（I）的本发明的茚衍生物能够选择性地调节过氧化物酶体增殖物激活受体（PPAR）的活性，引起无副作用，因此它们可用于治疗和预防由PPAR调节的病症， 代谢综合征如糖尿病，肥胖症，动脉硬化，高脂血症，高胰岛素血症和高血压，炎性疾病如骨质疏松症，肝硬化和哮喘以及癌症。
-
公开(公告)号：EP1756036A1
公开(公告)日：2007-02-28
申请号：EP05733516.8
申请日：2005-04-12
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY , JE IL Pharmaceutical Co., Ltd. , Korea Research Institute of Bioscience and Biotechnology , CJ Corp.
发明人： CHEON, Hyae Gyeong , YOO, Sung-Eun , KIM, Sung Soo , YANG, Sung-Don , KIM, Kwang-Rok , RHEE, Sang Dal , AHN, Jin Hee , KANG, Seung Kyu , JUNG, Won Hoon , PARK, Sung Dae , KIM, Nam Gee , KIM, Sun Mee , MO, Kil Woong , LEE, Jae Mok , KANG, Hye Jung , LEE, Koun Ho , KIM, Jong Hoon , LEE, Jeong-Hyung , KIM, Seung Jun
IPC分类号： C07C69/753
CPC分类号： C07D295/088 , C07C65/26 , C07C69/757 , C07C229/50 , C07C233/52 , C07C255/47 , C07C2601/14 , C07C2602/08 , C07D295/155
摘要： The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer.
-
3.发明授权
公开(公告)号：EP1330164B1
公开(公告)日：2005-12-07
申请号：EP01930295.9
申请日：2001-05-11
发明人： KIM, Sung Soo , PARK, In-Hwan , SHIN, Byung Chul , LEE, Soo Hong
摘要： The present invention relates to novel antibacterial agents wherin the lone pair electrons of nitrogen atoms of amine compounds with high boiling point or water-soluble polymer with basic nitrogen at the backbone or side chain are coordinated with silver ion, and antibacterial and deodorizing solution comprising them.Since the antibacterial agents of the present invention has silver (Ag) ion coordinated with the lone pair electrons of nitrogen atom, the problems of conventional silver (Ag) compounds, i.e., their ease discoloration in general waters such as tap water and industrial water, are solved, and the inherent antibacterial activity is maintained due to the stabilization of silver ion (Ag+). Also, since they are highly soluble in water, they can be prepared in liquid form to be used for antibacterial and deodorizing purposes.
-
4.发明公开
公开(公告)号：EP1330164A1
公开(公告)日：2003-07-30
申请号：EP01930295.9
申请日：2001-05-11
发明人： KIM, Sung Soo , PARK, In-Hwan , SHIN, Byung Chul , LEE, Soo Hong
摘要： The present invention relates to novel antibacterial agents wherin the lone pair electrons of nitrogen atoms of amine compounds with high boiling point or water-soluble polymer with basic nitrogen at the backbone or side chain are coordinated with silver ion, and antibacterial and deodorizing solution comprising them.Since the antibacterial agents of the present invention has silver (Ag) ion coordinated with the lone pair electrons of nitrogen atom, the problems of conventional silver (Ag) compounds, i.e., their ease discoloration in general waters such as tap water and industrial water, are solved, and the inherent antibacterial activity is maintained due to the stabilization of silver ion (Ag+). Also, since they are highly soluble in water, they can be prepared in liquid form to be used for antibacterial and deodorizing purposes.
-
5.发明公开
公开(公告)号：EP1009748A1
公开(公告)日：2000-06-21
申请号：EP99929924.1
申请日：1999-06-30
发明人： CHOI, Joong-Kwon , YUM, Eul, Kgun , KIM, Sung Soo , KANG, Seung Kyu , CHEON, Hyae Gyeong , KIM, Hyo, Jung
IPC分类号： C07D471/04 , A61K31/47
CPC分类号： C07D471/04
摘要： The present invention relates to 3-alkylpyrrolo[3,2-c]quinoline derivatives represented by formula (1), their pharmaceutically acceptable salts, process for preparation thereof, and pharmaceutical composition thereof for treating gastric ulcer. 3-Alkylpyrrolo[3,2-c]quinoline derivatives of the present invention and their salts which inhibit gastric acid secretion of mammal, can be used effectively as a treatment for gastric ulcer.
-
-
-
-
搜索结果
5 条记录 (耗时 0.021 秒)
