公开(公告)号：EP0867453A3

公开(公告)日：1999-01-20

申请号：EP98105659.1

申请日：1998-03-27

申请人： KYOWA HAKKO KOGYO CO., LTD.

发明人： Suga, Shigenori ,  Muroi, Kenichi ,  Kinoshita, Tadashi ,  Goto, Joji

IPC分类号： C08B37/08

CPC分类号： C08B37/0072 ,  C12P19/26

摘要： Highly purified sodium hyaluronate having a low content of pyrogen is obtained by adding a salt and a water-soluble organic solvent to a solution containing sodium hyaluronate, or to a sodium hyaluronate solution previously filtered through a positively charged filter, precipitating and sedimenting the sodium hyaluronate and taking out a supernatant to remove pyrogen.

摘要翻译： 通过向含有透明质酸钠的溶液中加入盐和水溶性有机溶剂或先前通过带正电的过滤器过滤的透明质酸钠溶液，使透明质酸钠沉淀并沉淀，得到高纯度的热原含量的透明质酸钠。 并取出上清液除去热原。

公开(公告)号：EP0867453A2

公开(公告)日：1998-09-30

申请号：EP98105659.1

申请日：1998-03-27

申请人： KYOWA HAKKO KOGYO CO., LTD.

发明人： Suga, Shigenori ,  Muroi, Kenichi ,  Kinoshita, Tadashi ,  Goto, Joji

IPC分类号： C08B37/08

CPC分类号： C08B37/0072 ,  C12P19/26

摘要： Highly purified sodium hyaluronate having a low content of pyrogen is obtained by adding a salt and a water-soluble organic solvent to a solution containing sodium hyaluronate, or to a sodium hyaluronate solution previously filtered through a positively charged filter, precipitating and sedimenting the sodium hyaluronate and taking out a supernatant to remove pyrogen.