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公开(公告)号：EP0867453A2
公开(公告)日：1998-09-30
申请号：EP98105659.1
申请日：1998-03-27
IPC分类号： C08B37/08
CPC分类号： C08B37/0072 , C12P19/26
摘要： Highly purified sodium hyaluronate having a low content of pyrogen is obtained by adding a salt and a water-soluble organic solvent to a solution containing sodium hyaluronate, or to a sodium hyaluronate solution previously filtered through a positively charged filter, precipitating and sedimenting the sodium hyaluronate and taking out a supernatant to remove pyrogen.
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2.发明公开DC-89 compounds and process for their preparation 失效DC-89-Verbindungen und Verfahren zu ihrer Herstellung。
公开(公告)号：EP0351865A2
公开(公告)日：1990-01-24
申请号：EP89113431.4
申请日：1989-07-21
发明人： Takahashi, Keiichi , Ichimura, Michio , Katsumata, Shigeo , Ogawa, Tatsuhiro , Morimoto, Makoto , Ashizawa, Tadashi , Kasai, Masaji , Muroi, Kenichi , Saito, Hiromitsu , Sano, Hiroshi , Yasuzawa, Toru
IPC分类号： C07D487/04 , C07D471/04 , A61K31/40 , A61K31/435 , C12P17/18
CPC分类号： C07D471/04 , C07D487/04
摘要： Novel DC-89 compounds represented by the general formula:
wherein X represents a single bond or -CH₂-; and when X represents a single bond, Y represents -CH₂Br or -CH₂Cl and when X represents -CH₂-, Y represents Br, are obtained by the present invention. The compounds have antibacterial and anti-tumor activity.摘要翻译： 由通式表示的新型DC-89化合物：其中X表示单键或-CH 2 - ; 当X表示单键时，Y表示-CH 2 Br或-CH 2 Cl，X表示-CH 2 - ，Y表示Br时，由本发明得到。 该化合物具有抗菌和抗肿瘤活性。
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公开(公告)号：EP0351865A3
公开(公告)日：1990-06-27
申请号：EP89113431.4
申请日：1989-07-21
发明人： Takahashi, Keiichi , Ichimura, Michio , Katsumata, Shigeo , Ogawa, Tatsuhiro , Morimoto, Makoto , Ashizawa, Tadashi , Kasai, Masaji , Muroi, Kenichi , Saito, Hiromitsu , Sano, Hiroshi , Yasuzawa, Toru
IPC分类号： C07D487/04 , C07D471/04 , A61K31/40 , A61K31/435 , C12P17/18
CPC分类号： C07D471/04 , C07D487/04
摘要： Novel DC-89 compounds represented by the general formula:
wherein X represents a single bond or -CH₂-; and when X represents a single bond, Y represents -CH₂Br or -CH₂Cl and when X represents -CH₂-, Y represents Br, are obtained by the present invention. The compounds have antibacterial and anti-tumor activity.-
公开(公告)号：EP0867453A3
公开(公告)日：1999-01-20
申请号：EP98105659.1
申请日：1998-03-27
IPC分类号： C08B37/08
CPC分类号： C08B37/0072 , C12P19/26
摘要： Highly purified sodium hyaluronate having a low content of pyrogen is obtained by adding a salt and a water-soluble organic solvent to a solution containing sodium hyaluronate, or to a sodium hyaluronate solution previously filtered through a positively charged filter, precipitating and sedimenting the sodium hyaluronate and taking out a supernatant to remove pyrogen.
摘要翻译： 通过向含有透明质酸钠的溶液中加入盐和水溶性有机溶剂或先前通过带正电的过滤器过滤的透明质酸钠溶液，使透明质酸钠沉淀并沉淀，得到高纯度的热原含量的透明质酸钠。 并取出上清液除去热原。
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公开(公告)号：EP0351865B1
公开(公告)日：1995-05-03
申请号：EP89113431.4
申请日：1989-07-21
发明人： Takahashi, Keiichi , Ichimura, Michio , Katsumata, Shigeo , Ogawa, Tatsuhiro , Morimoto, Makoto , Ashizawa, Tadashi , Kasai, Masaji , Muroi, Kenichi , Saito, Hiromitsu , Sano, Hiroshi , Yasuzawa, Toru
IPC分类号： C07D487/04 , C07D471/04 , A61K31/40 , A61K31/435 , C12P17/18
CPC分类号： C07D471/04 , C07D487/04
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