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公开(公告)号：EP0300294A3
公开(公告)日：1990-03-21
申请号：EP88110939.1
申请日：1988-07-08
发明人： Nakano, Hirofumi , Hara, Mitsunobu , Takahashi, Isami , Asano, Kozo , Iida, Takao , Morimoto, Makoto
CPC分类号： C12P1/06 , C12R1/465 , Y10S435/886
摘要： A novel compound, DC-107, is produced by culturing a microorganism belonging to the genus Streptomyces. It is useful as a medicine because of its antibacterial and anti-tumor activity.
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公开(公告)号：EP0300294B1
公开(公告)日：1993-11-03
申请号：EP88110939.1
申请日：1988-07-08
发明人： Nakano, Hirofumi , Hara, Mitsunobu , Takahashi, Isami , Asano, Kozo , Iida, Takao , Morimoto, Makoto
CPC分类号： C12P1/06 , C12R1/465 , Y10S435/886
摘要： A novel compound, DC-107, with the following physicochemical properties: (1) Molecular formula: C22H26N2O6S3 (2) Molecular weight: 510 Found by high resolution FAB mass spectrum : 511.1041 Calculated for C22H27N2O6S3 : 511.1031 (3) Melting point: 160 DEG C (decomposed) (4) Specific rotation: [ alpha ]25_D = 140 DEG (c=0.1, methanol) obtained by culturing a microorganism belonging to the genus Streptomyces. It is useful as a medicine because of its antibacterial and anti-tumor activity.
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公开(公告)号：EP0390181B1
公开(公告)日：1995-05-10
申请号：EP90106121.8
申请日：1990-03-30
IPC分类号： C07C49/755 , A61K31/21 , C07C229/08 , C07D207/16 , C07C327/22 , C07C69/96 , C07C69/007 , C07C255/50 , C07C309/66 , C07C309/73 , C07D307/68
CPC分类号： C07D213/79 , C07C50/36 , C07C69/00 , C07C69/96 , C07C205/57 , C07C229/08 , C07C229/36 , C07C255/57 , C07C271/12 , C07C271/28 , C07C309/66 , C07C309/73 , C07C327/32 , C07C2601/14 , C07C2603/00 , C07C2603/52 , C07D207/16 , C07D241/24 , C07D307/68
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公开(公告)号：EP0635479B1
公开(公告)日：1997-07-30
申请号：EP94115986.5
申请日：1990-03-30
IPC分类号： C07C69/78 , C07C69/96 , A61K31/235
CPC分类号： C07D213/79 , C07C50/36 , C07C69/00 , C07C69/96 , C07C205/57 , C07C229/08 , C07C229/36 , C07C255/57 , C07C271/12 , C07C271/28 , C07C309/66 , C07C309/73 , C07C327/32 , C07C2601/14 , C07C2603/00 , C07C2603/52 , C07D207/16 , C07D241/24 , C07D307/68
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公开(公告)号：EP0390181A2
公开(公告)日：1990-10-03
申请号：EP90106121.8
申请日：1990-03-30
IPC分类号： C07C49/755 , A61K31/21 , C07C229/08 , C07D207/16 , C07C327/22 , C07C69/96 , C07C69/007 , C07C255/50 , C07C309/66 , C07C309/73 , C07D307/68
CPC分类号： C07D213/79 , C07C50/36 , C07C69/00 , C07C69/96 , C07C205/57 , C07C229/08 , C07C229/36 , C07C255/57 , C07C271/12 , C07C271/28 , C07C309/66 , C07C309/73 , C07C327/32 , C07C2601/14 , C07C2603/00 , C07C2603/52 , C07D207/16 , C07D241/24 , C07D307/68
摘要： A UCN-1028D derivative represented by the formula:
has protein kinase C inhibitory activity and is expected to be used as an active ingredient in anti-tumor agents, etc.摘要翻译： 由下式表示的UCN-1028D衍生物：
具有蛋白激酶C抑制活性，预计可用作抗肿瘤剂等中的有效成分。 -
7.发明公开Novel compound DC-107 and process for its preparation 失效Verbindung DC-107和Verfahren zu deren Herstellung。
公开(公告)号：EP0300294A2
公开(公告)日：1989-01-25
申请号：EP88110939.1
申请日：1988-07-08
发明人： Nakano, Hirofumi , Hara, Mitsunobu , Takahashi, Isami , Asano, Kozo , Iida, Takao , Morimoto, Makoto
CPC分类号： C12P1/06 , C12R1/465 , Y10S435/886
摘要： A novel compound, DC-107, is produced by culturing a microorganism belonging to the genus Streptomyces. It is useful as a medicine because of its antibacterial and anti-tumor activity.
摘要翻译： 具有以下物理化学性质的新化合物DC-107：（1）分子式：C22H26N2O6S3（2）分子量：510通过高分辨率FAB质谱求出：511.1041 C22H27N2O6S3计算值：511.1031（3）熔点：160℃ C（分解）（4）比旋光度：通过培养属于链霉菌属的微生物获得的α25_D= 140°（c = 0.1，甲醇）。 由于其抗菌和抗肿瘤活性，它作为药物是有用的。
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公开(公告)号：EP0635479A1
公开(公告)日：1995-01-25
申请号：EP94115986.5
申请日：1990-03-30
IPC分类号： C07C69/78 , C07C69/96 , A61K31/235
CPC分类号： C07D213/79 , C07C50/36 , C07C69/00 , C07C69/96 , C07C205/57 , C07C229/08 , C07C229/36 , C07C255/57 , C07C271/12 , C07C271/28 , C07C309/66 , C07C309/73 , C07C327/32 , C07C2601/14 , C07C2603/00 , C07C2603/52 , C07D207/16 , C07D241/24 , C07D307/68
摘要： A UCN-1028D derivative represented by the formula:
has protein kinase C inhibitory activity and is expected to be used as an active ingredient in anti-tumor agents, etc.摘要翻译： 由下式表示的UCN-1028D衍生物：
具有蛋白激酶C抑制活性，预计可用作抗肿瘤剂等中的有效成分。 -
公开(公告)号：EP0504711A1
公开(公告)日：1992-09-23
申请号：EP92104079.6
申请日：1992-03-10
CPC分类号： C07J73/005
摘要： Disclosed is UCA1064-B, a compound represented by formula (I):
and having an antibacterial, antifungal and anti-tumor activity. UCA1064-B is produced by culturing a microorganism belonging to the genus Wallemia .摘要翻译： 公开了由式（I）表示的化合物UCA1064-B：并具有抗菌，抗真菌和抗肿瘤活性。 UCA1064-B是通过培养属于瓦勒米亚属的微生物生产的。
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公开(公告)号：EP0390181A3
公开(公告)日：1991-04-17
申请号：EP90106121.8
申请日：1990-03-30
IPC分类号： C07C49/755 , A61K31/21 , C07C229/08 , C07D207/16 , C07C327/22 , C07C69/96 , C07C69/007 , C07C255/50 , C07C309/66 , C07C309/73 , C07D307/68
CPC分类号： C07D213/79 , C07C50/36 , C07C69/00 , C07C69/96 , C07C205/57 , C07C229/08 , C07C229/36 , C07C255/57 , C07C271/12 , C07C271/28 , C07C309/66 , C07C309/73 , C07C327/32 , C07C2601/14 , C07C2603/00 , C07C2603/52 , C07D207/16 , C07D241/24 , C07D307/68
摘要： A UCN-1028D derivative represented by the formula:
has protein kinase C inhibitory activity and is expected to be used as an active ingredient in anti-tumor agents, etc.摘要翻译： 由下式表示的UCN-1028D衍生物：
具有蛋白激酶C抑制活性，预计可用作抗肿瘤剂等中的有效成分。
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