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公开(公告)号：EP2740804A1
公开(公告)日：2014-06-11
申请号：EP12822928.3
申请日：2012-07-27
CPC分类号： C12Q1/6837 , C12Q1/6853 , C12Q2525/301
摘要： Embodiments relate to a method of analyzing nucleic acid. The nucleic acid analysis method includes subjecting a sample to an amplifying reaction using the first primer and the second primer, reacting an amplification product with a nucleic acid probe, measuring presence/absence of a hybridization and/or a quantity thereof, and determining presence/absence of a target nucleic acid in the sample and/or a quantity of target nucleic acid present. The amplification product obtained with the first primer and/or second primer forms a first stem-and-loop structural body. With the detection of the presence/absence of the hybridization between a nucleic acid probe complementary to a sequence of the loop structure and the amplification product, and/or the amount thereof present, the nucleic acid analysis is carried out on the sample.
摘要翻译： 实施方案涉及分析核酸的方法。 核酸分析方法包括使用第一引物和第二引物对扩增反应进行扩增反应，使扩增产物与核酸探针反应，测定杂交的存在/不存在和/或其量，并确定存在/ 不存在样品中的靶核酸和/或存在的目标核酸的量。 用第一底漆和/或第二底漆获得的扩增产物形成第一茎 - 环结构体。 通过检测与环结构序列互补的核酸探针和扩增产物之间的杂交存在/不存在和/或其存在量，对样品进行核酸分析。
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2.发明公开POLYNUCLEOTIDE PROBE AND PRIMER ORIGINATING IN HEPATITIS E VIRUS OF JAPANESE, CHIPS HAVING THE SAME, KITS HAVING THE SAME AND METHOD OF DETECTING HEPATITIS E VIRUS USING THE SAME 审中-公开核苷酸和引物对原产于日本CHIPS这一点，所以试剂盒和检测方法的戊型肝炎病毒戊型肝炎病毒
公开(公告)号：EP1400588A1
公开(公告)日：2004-03-24
申请号：EP02741299.8
申请日：2002-06-25
CPC分类号： C12Q1/707 , C12Q2565/501 , C12Q2531/113
摘要： A polynucleotide probe including a sequence comprising at least eight nucleotides, the polynucleotide probe being used for detecting polynucleotides of hepatitis E virus.The sequence comprising at least eight nucleotides is hybridized with the polynucleotide of the hepatitis E virus, thereby, due to the hybridization, allowing the detection of the hepatitis E virus.
摘要翻译： 多核苷酸探针包括包含至少8个核苷酸的序列，被用于检测戊型肝炎virus.The序列的多核苷酸，其包含至少8个核苷酸杂交与戊型肝炎病毒的多核苷酸的多核苷酸探针，由此，由于杂交， 允许戊型肝炎病毒的检测。
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公开(公告)号：EP1375672A1
公开(公告)日：2004-01-02
申请号：EP02702736.6
申请日：2002-03-05
IPC分类号： C12Q1/68 , C12N15/09 , C12M1/00 , G01N33/53 , G01N33/543 , G01N33/566 , G01N33/576 , G01N37/00
CPC分类号： C12Q1/701
摘要： The present invention provides methods for obtaining information regarding nucleic acid from an individual and nucleic acid associated with a disease of the individual, in particular when the disease is associated with a pathogenic microorganism present within the individual. The present invention also provide probe-immobilized substrates, such as probe-immobilized chips, for use in the methods. In particular, the present invention provides methods and probe-immobilized substrates for obtaining information regarding responsiveness to a treatment for a disease of an individual.
摘要翻译： 本发明提供了获得关于来自个体的核酸和与个体疾病相关的核酸的信息的方法，特别是当疾病与个体内存在的致病微生物相关时。 本发明还提供了用于该方法的探针固定的基底，例如探针固定的芯片。 特别地，本发明提供了用于获得关于对个体疾病的治疗的反应性的信息的方法和探针固定的基质。
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4.发明公开POLYMORPHIC MARKER THAT CAN BE USED TO ASSESS THE EFFICACY OF INTERFERON THERAPY 有权多晶型标记，用来保证干扰素治疗的有效性DETERMINE
公开(公告)号：EP1436756A2
公开(公告)日：2004-07-14
申请号：EP02763042.5
申请日：2002-09-20
CPC分类号： C12Q1/6886 , C12Q2600/156
摘要： The present invention provides a polymorphic marker found in a region of the interferon receptor gene that can be used to assess the efficacy of interferon therapy. Thus, the present invention also relates to methods of assessing the efficacy of interferon therapy in an individual and means for accomplishing such a method.
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5.发明授权POLYMORPHIC MARKER THAT CAN BE USED TO ASSESS THE EFFICACY OF INTERFERON THERAPY 有权多晶型标记，用来保证干扰素治疗的有效性DETERMINE
公开(公告)号：EP1436756B1
公开(公告)日：2009-01-07
申请号：EP02763042.5
申请日：2002-09-20
CPC分类号： C12Q1/6886 , C12Q2600/156
摘要： The present invention provides a polymorphic marker found in a region of the interferon receptor gene that can be used to assess the efficacy of interferon therapy. Thus, the present invention also relates to methods of assessing the efficacy of interferon therapy in an individual and means for accomplishing such a method.
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