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公开(公告)号：EP2968278A1
公开(公告)日：2016-01-20
申请号：EP14720403.6
申请日：2014-03-14
IPC分类号： A61K31/4196 , A61K31/497 , A61K31/506 , A61P17/02 , C07D403/12
CPC分类号： C07D403/12 , A61K31/41 , A61K31/4196 , C07D207/325 , C07D207/33 , C07D213/50 , C07D231/12 , C07D233/64 , C07D249/08 , C07D257/04 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/12 , C07D487/10
摘要： The invention generally relates to the use of nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula (I) or a pharmaceutically acceptable salt thereof, wherein Ring A, X, R1, R2 and n are as defined and described herein, in a method for promoting wound healing in a subject.
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公开(公告)号：EP2968278B8
公开(公告)日：2019-05-22
申请号：EP14720403.6
申请日：2014-03-14
IPC分类号： A61K31/4196 , A61K31/497 , A61K31/506 , A61P17/02 , C07D403/12
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公开(公告)号：EP2968278B1
公开(公告)日：2018-12-12
申请号：EP14720403.6
申请日：2014-03-14
IPC分类号： A61K31/4196 , A61K31/497 , A61K31/506 , A61P17/02 , C07D403/12
CPC分类号： C07D403/12 , A61K31/41 , A61K31/4196 , C07D207/325 , C07D207/33 , C07D213/50 , C07D231/12 , C07D233/64 , C07D249/08 , C07D257/04 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/12 , C07D487/10
摘要： The invention generally relates to the use of nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula (I) or a pharmaceutically acceptable salt thereof, wherein Ring A, X, R1, R2 and n are as defined and described herein, in a method for promoting wound healing in a subject.
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