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1.发明公开CT SURROGATE BY AUTO-SEGMENTATION OF MAGNETIC RESONANCE IMAGES 有权CT-SURROGAT DURCH AUTOSEGMENTIERUNG VON MAGNETRESONANZBILDERN
公开(公告)号：EP2252204A1
公开(公告)日：2010-11-24
申请号：EP09718294.3
申请日：2009-02-25
CPC分类号： A61N5/103 , A61B5/055 , A61B6/032 , A61B6/037 , A61B6/4417 , A61B6/5247 , G06T7/33 , G06T7/38
摘要： When modeling anatomical structures in a patient for diagnosis or therapeutic planning, an atlas (26) of segmented co-registered CT and MRI anatomical structure reference images can be accessed, and an image of one or more such structures can be selected and overlaid with an MRI image of corresponding structure(s) in a clinical image of a patient. A user can click and drag landmarks or segment edges on the reference MRI image to deform the reference MRI image to align with the patient MRI image. Registration of a landmark in the patient MRI image to the reference MRI image also registers the patient MRI image landmark with a corresponding landmark in the co- registered reference CT image, and electron density information from the reference CT image landmark is automatically attributed to the corresponding registered patient MRI landmark.
摘要翻译： 当对患者进行诊断或治疗计划的解剖结构建模时，可以访问分段共同登记的CT和MRI解剖结构参考图像的图集（26），并且可以选择并覆盖一个或多个这样的结构的图像 在患者的临床图像中的相应结构的MRI图像。 用户可以点击并拖动参考MRI图像上的界标或段边缘，以使参考MRI图像变形以与患者MRI图像对准。 将患者MRI图像中的地标注册到参考MRI图像还将共同登记的参考CT图像中的患者MRI图像标记与相应的标记进行登记，并且来自参考CT图像标记的电子密度信息被自动归因于相应的 注册患者MRI地标。
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2.发明公开METHOD AND APPARATUS FOR SEGMENTATION OF AN OBJECT 审中-公开VERFAHREN UND VORRICHTUNG ZUR OBJEKTSEGMENTIERUNG
公开(公告)号：EP1430443A2
公开(公告)日：2004-06-23
申请号：EP02760496.6
申请日：2002-08-29
发明人： YOUNG, Stewart , PEKAR, Vladimir , WEESE, Juergen
IPC分类号： G06T5/00
CPC分类号： G06T7/149 , G06T7/12 , G06T2207/10072 , G06T2207/30101 , G06T2210/41
摘要： The invention relates to a method and an apparatus for segmentation of an object in a 2D or 3D image data set by extracting a path along the object. In order to obtain a higher accuracy and reliability, the method according to the invention comprises the steps of: a) selecting a start point (5) of the path (2) as first active point, b) adapting an adaptable model (40) to the object (1) in a first active section around the start point (5), c) finding the next point (58) of the selected region by the steps of: c1) copying the geometric model parameters of the adapted model (40) of the active point to a plurality of neighboring points (51-58) of the active point (5), c2) orienting a model (32) around each of said plurality of neighboring points (51-58) using said copied model parameters and, searching the closest object points (21-26) around each of said neighboring points (51-58) based on said model, c3) adapting the models to the found object points (21-26) for each neighboring point (51-58), c4) selecting the neighboring point (58) for which the adapted model (48) fits best to the object (1) as next point of the selected region and as next active point, and d) repeating step c) until an end point of the path or a predetermined number of iterations is reached. The invention may preferably be applied for vessel segmentation to create maximum intensity projections with overlapping/occluding vessels removed.
摘要翻译： 在二维或三维图像数据集中的对象，例如血管，被分割。 围绕示例性血管的起始点定义适应性模型，例如示例性圆筒模型，并适于或适合于血管。 围绕起始点定义多个候选下一活动点，并且围绕每个候选点定义适应性模型。 候选点周围的模型适用于血管。 根据拟合模型的结果，选择下一个活动点。 以这种方式，通过使一系列圆柱模型适应于血管的内表面来分割血管。
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3.发明授权A METHOD, AN APPARATUS, A SYSTEM AND A COMPUTER PROGRAM FOR TRANSFERRING SCAN GEOMETRY BETWEEN SUBSEQUENT SCANS 有权方法，设备，系统和计算机程序，用于传输扫描几何之间连续扫描
公开(公告)号：EP2041723B1
公开(公告)日：2012-10-10
申请号：EP07825855.5
申请日：2007-06-28
发明人： BYSTROV, Daniel , PEKAR, Vladimir , YOUNG, Stewart , BERGMANS, Cornelis, J., F., M. , VAN MUISWINKEL, Arianne
IPC分类号： G06T7/00
CPC分类号： G01R33/54 , G01R33/543 , G06T7/74 , G06T2207/30004 , G06T2207/30244
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公开(公告)号：EP1907055A2
公开(公告)日：2008-04-09
申请号：EP06780028.4
申请日：2006-07-10
发明人： KAUS, Michael , PEKAR, Vladimir , MCNUTT, Todd
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1037 , A61N5/1038 , A61N5/1065 , A61N2005/1061
摘要： A method and apparatus accounting for tumor motion during radiation therapy is provided. The method allows for radiation therapy treatments based on updated radiation therapy plans. For each fractionate radiation treatment that results in an updated radiation treatment, radiation treatment images are acquired, automatically segmented, and then subject to deformable registration to develop updated contours and an updated radiation therapy plan. The apparatus (1) includes a processing unit (3) that is connected to an imaging apparatus (5) that takes an image (6) of object (9) and a radiation apparatus (7) that radiates object (9) .
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5.发明公开INTERACTIVE ITERATIVE CLOSEST POINT ALGORITHM FOR ORGAN SEGMENTATION 审中-公开INTERAKTIVER ITERATIVER ALGORITHMUS DERNÄCHSTENPUNKTEFÜRORGANSEGMENTIERUNG
公开(公告)号：EP2415019A1
公开(公告)日：2012-02-08
申请号：EP10716055.8
申请日：2010-03-02
IPC分类号： G06T7/00
CPC分类号： G06T7/149 , G06T7/12 , G06T2207/10072 , G06T2207/20101 , G06T2207/20116 , G06T2207/30004
摘要： A system and method for segmenting an image of an organ. The system and method including selecting a surface model of the organ, selecting a plurality of points on a surface of an image of the organ and transforming the surface model to the plurality of points on the image.
摘要翻译： 用于分割器官的图像的系统和方法。 该系统和方法包括选择器官的表面模型，选择器官的图像表面上的多个点，并将表面模型转换成图像上的多个点。
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公开(公告)号：EP2186058A2
公开(公告)日：2010-05-19
申请号：EP08789483.8
申请日：2008-07-29
发明人： PEKAR, Vladimir , BYSTROV, Daniel
IPC分类号： G06T7/00
CPC分类号： G06K9/3216 , A61B6/503 , A61B6/504 , G06K2209/05 , G06T7/32 , G06T7/33 , G06T7/337 , G06T2207/10072 , G06T2207/20128 , G06T2207/30012
摘要： The invention relates to a system (100) for registering an atlas image from an atlas of multidimensional images with an objective image, the system comprising a generation unit (105) for generating a candidate transformation for transforming a first region of the atlas image, a transformation unit (110) for transforming the first region of the atlas image using the candidate transformation, a similarity unit (120) for computing a measure of similarity of the transformed first region of the atlas image and a corresponding first region of the objective image, an evaluation unit (130) for evaluating the candidate transformation using a criterion based on the computed measure of similarity and determining an optimal transformation based on the evaluation of the candidate transformation, an extension unit (140) for extending the optimal transformation of the first region of the atlas image to a second region of the atlas image, wherein the second region comprises the first region, thereby creating a registration transformation and a registration unit (150) for transforming the second region using the registration transformation, thereby registering the atlas image with the objective image. Advantageously, the system (100) does not require setting landmark positions in the objective image. A further advantage of the system (100) is that since the similarity measure is computed locally, i.e., based on the first region of the atlas image, the registration is fast and thus attractive for clinical use.
摘要翻译： 本发明涉及一种用于从具有客观图像的多维图像的图集登记图集图像的系统（100），该系统包括：生成单元（105），用于生成用于变换图集的第一区域的候选变换; 变换单元（110），用于使用候选变换来变换图集的第一区域;计算图像的变换的第一区域与对象图像的对应的第一区域的相似度的度量的相似度单元（120） 评估单元（130），用于使用基于所计算的相似度的测量的标准来评估候选变换，并且基于候选变换的评估来确定最佳变换;扩展单元（140），用于扩展第一区域的最优变换 的图谱图像到图集图像的第二区域，其中第二区域包括第一区域，由此c 重新配准注册变换和注册单元（150），用于使用注册变换来变换第二区域，从而将图像图像登记到客观图像中。 有利地，系统（100）不需要在目标图像中设置界标位置。 系统（100）的另一个优点在于，由于本地计算相似性度量，即基于图集图像的第一区域，登记是快速的，因此对于临床使用是有吸引力的。
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公开(公告)号：EP1927080A2
公开(公告)日：2008-06-04
申请号：EP06796024.5
申请日：2006-09-14
发明人： BYSTROV, Daniel , PEKAR, Vladimir
IPC分类号： G06T3/00
摘要： The invention relates to a registration method (100) of registering a second image dataset with a first image dataset on the basis of a set of landmarks, said registration method (100) comprising a weight-assigning step (125) for assigning a weight to each coordinate of each landmark from the set of landmarks and a registering step (145) for registering the second image dataset with the first image dataset on the basis of the weight assigned to the each coordinate. Choosing an appropriate set of landmarks and assigning an appropriate weight to each coordinate of each landmark from the set of landmarks can be used for optimizing selected displacements of a designated anatomical structure comprising elastic bodies and/or a plurality of independent rigid bodies in a sequence of image datasets. This enables rendering a sequence of views wherein the designated anatomical structure is not displaced off a viewing plane and/or a selected part of the designated anatomical structure is not displaced in a viewing plane.
摘要翻译： 本发明涉及一种登记方法（100），其基于一组地标将第二图像数据集与第一图像数据集进行登记，所述登记方法（100）包括权重分配步骤（125），用于将权重分配给 基于所述一组地标的每个地标的每个坐标，以及用于基于分配给每个坐标的权重，将所述第二图像数据集与所述第一图像数据集进行登记的登记步骤（145）。 可以使用适当的地标集合并从该地标集合向每个地标的每个坐标分配适当的权重，以优化包括弹性体和/或多个独立刚体的指定解剖结构的选定位移 图像数据集。 这使得能够呈现一系列视图，其中指定的解剖结构不会离开观察平面，和/或指定的解剖结构的所选部分不在观察平面中移位。
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公开(公告)号：EP1894163A2
公开(公告)日：2008-03-05
申请号：EP06745056.9
申请日：2006-05-31
发明人： KAUS, Michael , MCNUTT, Todd , PEKAR, Vladimir
CPC分类号： G06T7/30
摘要： A method for selecting vertices for performing deformable registration of imaged objects is provided. The selected vertices form corresponding pairs, each pair including a vertex from a first imaged object and a vertex from a second imaged object. The corresponding vertex pairs are sorted in order of distance between the vertices making up the corresponding vertex pair. The corresponding vertex pair with the greatest distance is given top priority. Corresponding vertex pairs that lie within a selected distance from the selected corresponding vertex pair are discarded. In this manner, the number of vertex pairs used for deformable registration of the imaged objects is reduced and therefore allows for processing times that are clinically acceptable.
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9.发明公开METHOD OF MODEL-BASED ELASTIC IMAGE REGISTRATION FOR COMPARING A FIRST AND A SECOND IMAGE 审中-公开程序用于确定弹性模型的照片ON比较基础两张图片的
公开(公告)号：EP1894161A2
公开(公告)日：2008-03-05
申请号：EP06765744.5
申请日：2006-06-14
CPC分类号： G06T3/0081 , G06T7/33 , G06T2207/30004
摘要： The invention aims at improving the point-based elastic registration paradigm. Point-based elastic registration is typically carried out by finding corresponding point landmarks (2, 4) in both images and using the point correspondences as constraints to interpolate the global displacement field. A limitation of this approach is that it only ensures the correspondences between structures where point landmarks (2, 4) can be identified. Alternative concepts are limited by high computational costs for optimization. The concept of the invention provides a method and a system (1) wherein additional deformation field constraints are imposed by: partitioning (PART (IS, IT)) one or more restricted structures corresponding in the first (3) and the second (5) image and imposing additional constraints (ƒAddpart) derived from a-priori-knowledge to the one or more restricted structures. Preferred examples are i) pairs of interactively defined point landmarks (25), ii) landmarks resulting from automatic identification of corresponding structures in form of a line (23) or an area (27) or a form or a boundary (29, Fig. 3) thereof, iii) different material properties (tissuel, tissue2) of corresponding structures, iv) physiological constraints establishing more general correspondences.
摘要翻译： 本发明的目的是改善基于点的弹性配准范例。 基于点的弹性配准是通过寻找对应点的地标（2,4）两个图像，并用对应点作为约束条件来内插所述全球位移场下进行。 这种方法的一个限制是它仅做确保其中点的地标（2,4）可以被识别的结构之间的对应关系。 替代概念被用于优化的高计算成本的限制。 本发明的构思提供一种方法和一种系统（1）worin附加变形字段约束通过强加：分区（部分（i 取值，I Ť））的一个或 更受限制的结构中的第一个（3）和第二（5）图像相应的和强加额外限制（F 添加 部分）从先验知识导出到所述一个 或多个限制的结构。 优选的实例是：i）对交互地定义的点的地标（25），ⅱ）标志所得从自动识别在一个线（23的形式）或在区域（27）或一个窗体或边界（29，
图3 ）它们，ⅲ）不同的材料特性相应的结构的（组织1个组织2），ⅳ）生理约束建立更一般的对应关系。 -
公开(公告)号：EP1371013A2
公开(公告)日：2003-12-17
申请号：EP02700508.1
申请日：2002-02-20
发明人： WEESE, Juergen , PEKAR, Vladimir , KAUS, Michael
IPC分类号： G06T5/00
CPC分类号： G06T7/0012 , G06T7/12 , G06T7/149 , G06T2207/10072 , G06T2207/30012
摘要： A method of segmenting a selected region from a multi-dimensional dataset, which method comprises the steps of setting up a shape model representing the general outline of the selected region and setting up an adaptive mesh. The adaptive mesh represents an approximate contour of the selected region. The adaptive mesh is initialized on the basis of the shape model. Furthermore, the adaptive mesh is deformed in dependence on the shape model and on feature information of the selected region.
摘要翻译： 一种从多维数据集分割所选区域的方法，该方法包括以下步骤：设置表示所选区域的总体轮廓的形状模型并设置自适应网格。 自适应网格表示所选区域的近似轮廓。 基于形状模型初始化自适应网格。 此外，自适应网格根据形状模型和所选区域的特征信息而变形。
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