NOVEL MUTANT MICROORGANISM PRODUCING SUCCINIC ACID SIMULTANEOUSLY USING SUCROSE AND GLYCEROL, AND METHOD FOR PREPARING SUCCINIC ACID USING SAME
    1.
    发明公开
    NOVEL MUTANT MICROORGANISM PRODUCING SUCCINIC ACID SIMULTANEOUSLY USING SUCROSE AND GLYCEROL, AND METHOD FOR PREPARING SUCCINIC ACID USING SAME 有权
    NEW突变微生物琥珀酸与琥珀酸的生产,使蔗糖和甘油和方法的同时使用PRODUCTION

    公开(公告)号:EP2612905A2

    公开(公告)日:2013-07-10

    申请号:EP11822105.0

    申请日:2011-08-30

    IPC分类号: C12N1/21 C12N15/52 C12P7/40

    摘要: The present invention relates to a succinic acid-producing mutant microorganism that is able to utilize sucrose and glycerol simultaneously as carbon sources. More particularly, the present invention relates to a succinic acid-producing mutant microorganism that is able to utilize sucrose and glycerol simultaneously for succinic acid production, the mutant organism being obtained by relieving the mechanism of sucrose-mediated catabolite repression of glycerol in a succinic acid-producing microorganism. As described above, when the succinic acid-producing mutant microorganism is cultured, it utilizes sucrose and glycerol simultaneously so that succinic acid can be produced with high productivity in a maximum yield approaching the theoretical yield while the production of byproducts is minimized. In addition, according to the present invention, various reduced chemicals which have been produced in low yields in conventional methods can be more effectively produced.

    摘要翻译: 本发明涉及一种产琥珀酸微生物突变体确实能够利用蔗糖和甘油同时作为碳源。 更具体地,本发明涉及一种产琥珀酸微生物突变体也能够利用蔗糖和甘油同时用于琥珀酸生产,所述突变体有机体由缓和甘油的蔗糖介导的分解代谢物抑制的机制在琥珀酸获得 - 生产微生物。 如上所述,当产生琥珀酸的突变体微生物进行培养时,它利用蔗糖和甘油同时所以也琥珀酸可以以高生产率在最大产率接近理论产率而生产的副产物最小化产生的。 此外,雅鼎在本发明中,已在低产量被生产中的常规方法减少各种化学品可以更有效地生产。