公开(公告)号：EP2711014A2

公开(公告)日：2014-03-26

申请号：EP12784901.6

申请日：2012-05-17

申请人： Korea Research Institute of Bioscience and Biotechology

发明人： KIM, Jae Wha ,  AHN, Kyung Seop ,  KANG, Ho Bum ,  OH, Sei Ryang ,  GO, Jae Jong ,  KIM, Joo Heon ,  SUN, Jang Mi ,  SONG, Jae Sung ,  OH, Hyun Woo ,  JI, Da Jung

IPC分类号： A61K36/83 ,  A61K31/357 ,  A61P17/00

CPC分类号： C07D493/08 ,  A23L2/52 ,  A23L7/198 ,  A23L33/105 ,  A61K9/0019 ,  A61K9/0095 ,  A61K9/2018 ,  A61K9/4858 ,  A61K31/357 ,  A61K36/83 ,  A61K47/26 ,  A61K2236/00

摘要： The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of Daphne genkwa, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.