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公开(公告)号：EP3167068A4
公开(公告)日：2018-03-21
申请号：EP15818880
申请日：2015-05-06
发明人： COLLET CHRISTOPHE , WATERS GUY WILLIAM , BROMLEY JASON CARL , YANG JUSTIN YI , WILSON JAROD NATHAN
摘要： Processes, as well as associated systems and computer program (software) products, are disclosed for the biological conversion of CO into desired end products such as ethanol. The control methodologies used for these processes can advantageously result in a reduced time required for a batch operation or other initial operating period, prior to achieving a continuous operation, which may be demarcated either by the addition of fresh culture medium at a defined flow rate or by another process initiation target. The control methodologies may alternatively, or in combination, improve a process performance parameter, such as productivity of the desired end product or bacterial growth rate, during this batch operation or other initial operating period.
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公开(公告)号：EP2524046A4
公开(公告)日：2013-10-23
申请号：EP11733140
申请日：2011-01-14
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公开(公告)号：EP3209786A4
公开(公告)日：2018-06-06
申请号：EP15852490
申请日：2015-10-22
发明人： TREVETHICK SIMON RICHARD , BROMLEY JASON CARL , WATERS GUY WILLIAM , KOEPKE MICHAEL , TRAN LOAN PHUONG , JENSEN OVERGAARD RASMUS
IPC分类号： C12P7/06 , C12M1/00 , C12M3/00 , C12P1/00 , C12P7/04 , C12P7/14 , C12P7/18 , C12P7/28 , C12P7/54
摘要： Multi-stage, biological processes and systems for converting a C1 carbon source to desired end products are described. The processes comprise dividing a gaseous C1-containing substrate, in parallel, among multiple bioreactor stages. Liquid products are successively fed, in series, from a first bioreactor stage to downstream bioreactor stages. Operation can be simplified by avoiding the requirement for microorganism separation and recycle at each stage. In addition, overall vapor-liquid mass transfer for the combined stages is very favorable, leading to high end product productivity with comparably low byproduct metabolite productivity.
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公开(公告)号：EP3210012A4
公开(公告)日：2018-05-23
申请号：EP15853236
申请日：2015-10-21
发明人： HEIJSTRA BJORN DANIEL , SIMPSON SEAN DENNIS , BOURDAKOS NICHOLAS , BROMLEY JASON CARL , YAP KAI-MING
IPC分类号： G01N30/86 , C12M1/34 , C12M3/00 , C12N1/20 , C12P7/06 , C12R1/145 , G01N30/62 , G01N30/88 , G01N33/00
CPC分类号： C12Q1/02 , C12M21/04 , C12M21/12 , C12M23/44 , C12M29/18 , C12M41/00 , C12M41/12 , C12M41/26 , C12M41/34 , C12P7/065 , G01N30/02 , G01N30/462 , G01N30/8658 , G01N30/88 , G01N2030/0095 , Y02E50/343
摘要： Apparatuses and associated methods are described for the efficient evaluation of Cl-containing substrates, and especially for such evaluation conducted locally, or on-site, at a prospective facility for implementation of a biological conversion process for desired end product using a Cl carbon source. The exact composition of a given, industrial Cl-containing substrate, as well as the range in composition fluctuations, are generally difficult to reproduce at a remote facility (e.g., a laboratory or a pilot-scale or demonstration-scale process), as required for the accurate prediction/modeling of com′mercial performance to justify large capital expenditures for commercial scale-up.
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公开(公告)号：EP2449121A4
公开(公告)日：2014-01-01
申请号：EP10794423
申请日：2010-07-02
发明人： BARKER WILL DAVID , HEIJSTRA BJORN DANIEL , CHAN WING CHUEN , MIHALCEA CHRISTOPHE DANIEL , TRAN PHUONG LOAN , COLLET CHRISTOPHE , BROMLEY JASON CARL , AL-SINAWI BAKIR
摘要： The invention relates to the production of products such as alcohols and acids by microbial fermentation, particularly microbial fermentation of substrates comprising CO. It more particularly relates to methods and systems for improving efficiency of production products by microbial fermentation. In particular embodiments, the invention provides a method of controlling substrate supply, such that production of desired metabolites is optimised.
摘要翻译： 本发明涉及通过微生物发酵生产诸如醇和酸的产品，特别是涉及包含CO的底物的微生物发酵。更具体地涉及通过微生物发酵提高生产产品效率的方法和系统。 在具体实施方案中，本发明提供了一种控制底物供应的方法，使得所需代谢物的产生被优化。
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公开(公告)号：EP2519641A4
公开(公告)日：2013-03-20
申请号：EP10814012
申请日：2010-09-03
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