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公开(公告)号：EP4288527A1
公开(公告)日：2023-12-13
申请号：EP22705674.4
申请日：2022-02-04
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2.发明公开
公开(公告)号：EP3762724A1
公开(公告)日：2021-01-13
申请号：EP19713303.6
申请日：2019-03-11
发明人： ERICKSON, Stephen , GIL, Jose S. , NGUYEN, Minh Mindy Bao , ANDERSON, Dwight L. , HAHN, Wendy , PAULSON, John
IPC分类号： G01N33/569 , C12N1/02 , C12N9/50
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公开(公告)号：EP3737745A1
公开(公告)日：2020-11-18
申请号：EP19706781.2
申请日：2019-01-14
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4.发明公开METHODS AND SYSTEMS FOR RAPID DETECTION OF MICROORGANISMS USING FREE ANTIBODIES 审中-公开方法和系统通过自由抗体的微生物快速检测
公开(公告)号：EP3108249A2
公开(公告)日：2016-12-28
申请号：EP15706660.6
申请日：2015-02-18
发明人： ANDERSON, Dwight Lyman , HOPKINS, Ben Barrett , GIL, Jose S. , ERICKSON, Stephen Eric , KOVACHEVA, Ekaterina
IPC分类号： G01N33/569
CPC分类号： C12Q1/24 , C12Q1/04 , G01N2469/10
摘要： Disclosed herein are methods and systems for detection of a microorganism of interest using an amplification assay. The methods and systems utilize the specificity of binding agents, such as antibodies, to rapidly detect low levels of a specific microorganism present in a sample. In certain embodiments, antibodies are bound to a large number of the available binding sites on a microorganism.
摘要翻译： 公开用于检测使用在扩增测定感兴趣的微生物的方法和系统。 该方法和系统利用结合剂，颜色的特异性：如抗体，来检测样品中存在的一个特定的快速微生物的低的水平。 在某些实施方案中，抗体结合到大量上的微生物的可用结合位点。
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公开(公告)号：EP4028540A1
公开(公告)日：2022-07-20
申请号：EP20781180.3
申请日：2020-09-11
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公开(公告)号：EP3108249B1
公开(公告)日：2019-01-02
申请号：EP15706660.6
申请日：2015-02-18
发明人： ANDERSON, Dwight Lyman , HOPKINS, Ben Barrett , GIL, Jose S. , ERICKSON, Stephen Eric , KOVACHEVA, Ekaterina
IPC分类号： G01N33/569
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7.发明授权
公开(公告)号：EP3108014B1
公开(公告)日：2018-12-05
申请号：EP15719021.6
申请日：2015-02-18
IPC分类号： C12Q1/70
CPC分类号： C12Q1/70 , C12N15/86 , C12N2795/10121 , C12N2795/10131 , C12N2795/10143 , C12N2795/10221 , C12N2795/10231 , C12N2795/10243
摘要： Disclosed herein are methods and systems for rapid detection of microorganisms in a sample, without culturing for enrichment of the microorganism. A modified bacteriophage is also disclosed which comprises a non-native indicator gene in the late gene region. The indicator product is not a fusion protein. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.
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公开(公告)号：EP2817422A1
公开(公告)日：2014-12-31
申请号：EP13751965.8
申请日：2013-02-21
发明人： ANDERSON, Dwight Lyman , CONRAD, Andrew J. , ERICKSON, Stephen Eric , GIL, Jose S. , HOPKINS, Ben Barrett
CPC分类号： G01N33/56911 , C12Q1/70 , G01N33/54326 , G01N33/569 , G01N33/581 , G01N2333/90241 , G01N2469/10
摘要： Disclosed are methods and systems for the isolation and detection of microbes from a sample. The use of binding agents for isolation of a microbe of interest from a sample are described. In certain embodiments, the methods use ribosome-based and/or bacteriophage-based amplification of the signal in detection of bacteria and other microorganisms. For example, embodiments of the present invention can achieve total amplification of at least 10,000 from a single infected cell.
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10.发明公开
公开(公告)号：EP3784786A1
公开(公告)日：2021-03-03
申请号：EP19732756.2
申请日：2019-04-24
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