-
1.发明公开DERIVES DE PYRIDO-PYRIDO-PYRROLO PYRROLO-INDOLE ET PYRIDO-PYRROLO PYRROLO CARBAZOLE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT 审中-公开PYRIDOPYRIDOPYRROLOPYRROLOINDOL- AND PYRIDOPYRROLOPYRROLOCARBAZOLDERIVATE，其制造方法和方法衍生物技术含有的药物组合物
公开(公告)号：EP1409486A1
公开(公告)日：2004-04-21
申请号：EP02767534.7
申请日：2002-06-28
发明人： PRUDHOMME, Michelle , MARMINON, Christelle , ROUTIER, Sylvain , COUDERT, Gérard , MEROUR, Jean-Yves , HICKMAN, John , PIERRE, Alain , RENARD, Pierre , PFEIFFER, Bruno
IPC分类号： C07D471/22 , C07D498/22 , A61K31/44
CPC分类号： C07H15/252
摘要： Compounds of formula (I) wherein: WI and W2 represent, with the carbon atoms to which they are bound, a phenyl group or a pyridinyl group, and at least one of the groups W1 or W2 represent a pyridinyl group; R1 and R2 each represent a group of formula U-V as defined in the description, X and X1 each represent a hydrogen atom, a hydroxy, alkoxy, mercapto or alkylthio group; Y and Y1 each represent a hydrogen atom; or X and Y, X1 and Y1 represent, together with the carbon atom that they include, a carbonyl or thiocarbonyl group; R4 and R5 are as defined in the description; Q1, Q2 represent a hydrogen atom, or Q1 and Q2, together with the carbon atoms that they include, form an aromatic link. The inventive compounds are used in medicaments.
-
2.发明公开NOUVEAUX DERIVES DE 1,4 BENZODIOXINO 2,3-e ISOINDOLE SUBSTITUES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT 有权取代的[1,4]苯并二恶英并[2,3-E]异吲哚衍生物，PROCESS FOR它们的生产和药物组合物
公开(公告)号：EP1587810A1
公开(公告)日：2005-10-26
申请号：EP03809363.9
申请日：2003-10-17
发明人： COUDERT, Gérard , AYERBE, Nathalie , LEPIFRE, Franck , ROUTIER, Sylvain , CAIGNARD, Daniel-Henri , RENARD, Pierre , HICKMAN, John , PIERRE, Alain , LEONCE, Stéphane
IPC分类号： C07D498/14 , C07D498/22 , C07D491/14 , C07D487/04 , A61P35/00 , A61K31/5365
CPC分类号： C07D471/14 , C07D487/04 , C07D491/14
摘要： The invention concerns compounds of formula (I), wherein: A is such as described in the description; Y represents a group selected among an oxygen atom or a methylene group; R2 represents a hydrogen atom, in which case: R3 represents a group selected among a hydrogen atom, a C1-C6 linear or branched alkyl, aryl, linear or branched C1-C6 arylalkyl group, or SO2CF3, or R2 and R3 form a bond; R1 represents a group selected among a hydrogen atom, a C1-C6 linear or branched alkyl, aryl, linear or branched C1-C6 arylalkyl group, or a linear or branched C1-C6 alkylene chain; Z1 and Z2 represent each a hydrogen atom or Z1 and Z2 form together, with the carbon atoms bearing them, a phenyl group. The invention is useful for preparing medicines.
-
3.发明授权NOUVEAUX DERIVES DE 1,4 BENZODIOXINO 2,3-e ISOINDOLE SUBSTITUES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT 有权取代¬1,4|BENZODIOXIN¬2,3-E |异吲哚衍生物，工艺作为生产，药物组合物
公开(公告)号：EP1587810B1
公开(公告)日：2006-11-08
申请号：EP03809363.9
申请日：2003-10-17
发明人： COUDERT, Gérard , AYERBE, Nathalie , LEPIFRE, Franck , ROUTIER, Sylvain , CAIGNARD, Daniel-Henri , RENARD, Pierre , HICKMAN, John , PIERRE, Alain , LEONCE, Stéphane
IPC分类号： C07D498/14 , C07D498/22 , C07D491/14 , C07D487/04 , A61P35/00 , A61K31/5365
CPC分类号： C07D471/14 , C07D487/04 , C07D491/14
摘要： The invention concerns compounds of formula (I), wherein: A is such as described in the description; Y represents a group selected among an oxygen atom or a methylene group; R2 represents a hydrogen atom, in which case: R3 represents a group selected among a hydrogen atom, a C1-C6 linear or branched alkyl, aryl, linear or branched C1-C6 arylalkyl group, or SO2CF3, or R2 and R3 form a bond; R1 represents a group selected among a hydrogen atom, a C1-C6 linear or branched alkyl, aryl, linear or branched C1-C6 arylalkyl group, or a linear or branched C1-C6 alkylene chain; Z1 and Z2 represent each a hydrogen atom or Z1 and Z2 form together, with the carbon atoms bearing them, a phenyl group. The invention is useful for preparing medicines.
-
-
搜索结果
3 条记录 (耗时 0.01 秒)
