公开(公告)号：EP2575597A4

公开(公告)日：2017-01-04

申请号：EP11787272

申请日：2011-05-24

Applicant: MASSACHUSETTS GEN HOSPITAL

Inventor： TEARNEY GUILLERMO J ,  BOUMA BRETT E ,  YOO HONGKI ,  SHISHKOV MILEN ,  GARDECKI JOSEPH ,  SHUBOCHKIN ROMAN ,  MORSE THEODORE ,  JAFFER AMIN FAROUC

IPC: A61B5/00 ,  G01B9/02 ,  G01N21/64

CPC classification number: A61B5/0084 ,  A61B5/0066 ,  A61B5/0071 ,  A61B5/6852 ,  G01B9/02029 ,  G01B9/0205 ,  G01B9/02091 ,  G01N21/4795 ,  G01N21/64 ,  G01N21/6456 ,  G01N21/65 ,  G01N2201/0866

Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.

公开(公告)号：EP2575591A4

公开(公告)日：2017-09-13

申请号：EP11790465

申请日：2011-06-03

Applicant: MASSACHUSETTS GEN HOSPITAL

Inventor： TEARNEY GUILLERMO J ,  BOUMA BRETT E ,  GORA MICHALINA ,  SUTER MELISSA ,  YOO HONGKI ,  SHISHKOV MILEN

IPC: A61B1/227 ,  A61B1/24 ,  G01B9/02

CPC classification number: A61B1/00082 ,  A61B1/00165 ,  A61B1/00179

Abstract: In accordance with exemplary embodiments of the present disclosure, device and method can be provided which can facilitate imaging of biological tissues, e.g., luminal organs in vivo, using optical techniques. The exemplary device can include different designs an features of one or more catheters, which can illuminate the tissues, and collect signals from the inside of the lumen. In another exemplary embodiment according to the present disclosure, a balloon-catheter can be provided with the flexible neck, which can absorb most of the bending. According to still another exemplary embodiments of the present disclosure, a balloon-catheter tethered capsule can be provided, and according a yet further exemplary embodiment, a structured balloon design can be provided with one or more protuberances, thus enabling imaging of the structures in close contact, e.g., without compressing of the tissue.

Abstract translation: 根据本公开的示例性实施例，可以提供可以利用光学技术促进生物组织例如体内腔内器官成像的装置和方法。 该示例性装置可以包括不同设计，一个或多个导管的特征，其可以照亮组织，并从内腔收集信号。 在根据本公开的另一个示例性实施例中，气囊导管可以设置有柔性颈部，其可以吸收大部分弯曲。 根据本公开的又一个示例性实施例，可以提供气囊导管系留胶囊，并且根据又一个示例性实施例，结构化气囊设计可以设置有一个或多个突起，从而使得能够近距离地对结构进行成像 接触，例如，不压缩组织。