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公开(公告)号:EP2438167A4
公开(公告)日:2013-11-06
申请号:EP10782840
申请日:2010-06-04
发明人: GAMBLE JENNIFER , VADAS MATHEW , GOODALL GREGORY , YOUNG JENNIFER
IPC分类号: C12N15/113 , A61K48/00 , A61P9/10 , A61P35/00 , C07H21/02
CPC分类号: C12N15/113 , A61K31/7088 , A61K31/7105 , C12N2310/113 , C12N2310/141 , C12N2320/30 , C12N2320/50 , C12N2330/10 , C12Q1/6883 , C12Q2600/158 , C12Q2600/178 , G01N33/6893 , G01N2800/7014
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公开(公告)号:EP1290182A4
公开(公告)日:2006-01-11
申请号:EP01929118
申请日:2001-05-11
发明人: VADAS MATHEW , GAMBLE JENNIFER , XIA PU , WANG LIJUN
IPC分类号: C12N15/09 , A61K31/13 , A61K31/133 , A61K35/14 , A61K38/00 , A61K45/00 , A61P35/00 , A61P43/00 , C12N5/06 , C12N5/10 , C12N9/12 , C12N15/54 , C12Q1/02 , C12Q1/48 , C12Q1/68
CPC分类号: C12N9/1205 , A61K31/13 , A61K38/00
摘要: The present invention relates generally to a method of modulating the growth of cells and, more particularly, to a method of down-regulating the growth of neoplastic cells. The present invention is useful, inter alia, in the therapeutic and/or prophylactic treatment of cancers such as, but not limited to, solid cancers such as cancers of the colon, stomach, lung, brain, bone, oesophagus, pancreas, breast, ovary or uterus.
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3.SPHINGOSINE KINASE INTERACTS WITH TRAF2 AND MODULATES TUMOR NECROSIS FACTOR-INDUCED CELLULAR ACTIVITY 审中-公开
标题翻译: 鞘氨醇激酶与TRAF2相互作用并调制该肿瘤坏死因子诱导的细胞活性公开(公告)号:EP1404364A4
公开(公告)日:2005-09-28
申请号:EP02732213
申请日:2002-06-03
发明人: XIA PU , WANG LIJUN , VADAS MATHEW , GAMBLE JENNIFER , MORETTI PAUL , PITSON STUART
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07K14/715 , C12N5/06 , C12N9/12 , C12Q1/02 , C12Q1/48 , G01N33/15 , A61K39/395 , A61K38/19 , A61K38/45
CPC分类号: C12N9/1205 , A61K38/00 , C07K14/7151
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