公开(公告)号：EP3202759A4

公开(公告)日：2018-05-09

申请号：EP15847985

申请日：2015-09-24

申请人： MEGABIOWOOD CO LTD

发明人： PARK KI DUK ,  LEE CHANGJOON JUSTIN ,  KIM DONG JIN ,  PAE AE NIM ,  CHOO HYUN AH ,  MIN SUN JOON ,  KANG YONG KOO ,  KIM YUN KYUNG ,  SONG HYO JUNG ,  CHOI JI WON ,  NAM MIN HO ,  HEO JUN YOUNG ,  YEON SEUL KI ,  JANG BO KO ,  JU EUN JI ,  JO SEON MI ,  PARK JONG-HYUN

IPC分类号： A61K31/16 ,  A61K31/167 ,  C07C231/12 ,  C07C237/04 ,  C07C237/06 ,  C07C237/20 ,  C07C309/04

CPC分类号： C07C237/06 ,  A61K31/16 ,  A61K31/167 ,  C07C231/12 ,  C07C237/04 ,  C07C237/20 ,  C07C309/04

摘要： The present disclosure relates to an ±-aminoamide derivative compound and a pharmaceutical composition containing the same. According to various embodiments of the present disclosure, provided is a therapeutic agent which can overcome the disadvantages of existing drugs used as a MAO-B inhibitor and, specifically, reversibly inhibits MAO-B through a non-covalent bond so as to alleviate or eliminate the side effects of the existing drugs which exhibit a therapeutic effect by irreversibly acting via a covalent bond with MAO-B. Particularly, a new compound having superior stability and efficacy compared to the existing reversible MAO-B inhibitors may be provided.