专利检索 ap:("MERCK SHARP & DOHME") AND inv:"MANDAL AMIT K" 第 1 页

1.

发明公开
PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS 审中-公开
标题翻译：吡唑并[1,5-A]嘧啶ALS mTOR抑制剂

公开(公告)号：EP2525659A4

公开(公告)日：2013-08-28

申请号：EP11735040

申请日：2011-01-18

申请人： MERCK SHARP & DOHME

发明人： SIDDIQUI M ARSHAD , NAN YANG , PATEL MEHUL F , REDDY PANDURANGA ADULLA P , MANSOOR UMAR FARUK , MENG ZHAOYANG , VITHARANA LALANTHI DILRUKSHI , ZHAO LIANYUN , MANDAL AMIT K , LIU DUAN , TANG SHUYI , MCRINER ANDREW , BELANGER DAVID B , CURRAN PATRICK J , DAI CHAOYANG , ANGELES ANGIE R , YANG LIPING , DANIELS MATTHEW HERSH

IPC分类号： A01N43/90

CPC分类号： C07D471/08 , C07D487/04 , C07D487/08 , C07D491/147 , C07D498/08 , C07D513/08 , C07D519/00

摘要： The present invention provides Pyrazolopyrimidine Compounds of Formula (I): wherein L, T, Z, U, V, W, R3, R6, R7, R8, and m are as defined herein, and pharmaceutically acceptable salts of such Pyrazolopyrimidine Compounds. The Pyrazolopyrimidine Compounds are useful in the treatment of cancer and other diseases or disorders wherein mTOR is deregulated.

2.

发明公开
NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS 有权
标题翻译： NEW [1,5-A]嘧啶衍生物作为抑制剂MTOR

公开(公告)号：EP2608669A4

公开(公告)日：2014-01-22

申请号：EP11820438

申请日：2011-08-22

申请人： MERCK SHARP & DOHME

发明人： ZHAO LIANYUN , LIU DUAN , TANG SHUYI , MANDAL AMIT K , MANSOOR UMAR FARUK , VITHARANA LALANTHI DILRUKSHI , REDDY PANDURANGA ADULLA P , SIDDIQUI M ARSHAD

IPC分类号： A01N43/42 , A61K31/52

CPC分类号： C07D487/04 , A61K31/519 , A61K31/5377 , A61K45/06

3.

发明公开
FUSED TRICYCLIC INHIBITORS OF MAMMALIAN TARGET OF RAPAMYCIN 有权
标题翻译：雷帕霉素靶标在哺乳动物体内的浓缩三环杀伤剂

公开(公告)号：EP2608668A4

公开(公告)日：2014-07-09

申请号：EP11820437

申请日：2011-08-22

申请人： MERCK SHARP & DOHME

发明人： MENG ZHAOYANG , REDDY PANDURANGA ADULLA P , SIDDIQUI M ARSHAD , MANDAL AMIT K , LIU DUAN , ZHAO LIANYUN , MCRINER ANDREW

IPC分类号： C07D471/14 , A61K31/4375 , A61P35/00 , C07D519/00

CPC分类号： C07D471/14 , C07D498/08 , C07D519/00