公开(公告)号：EP1734992B1

公开(公告)日：2011-09-28

申请号：EP05705920.6

申请日：2005-01-19

申请人： Merial Limited

发明人： POULET, Hervé ,  BARRAL, Denis

IPC分类号： A61K39/125 ,  C12Q1/70

CPC分类号： A61K39/12 ,  A61K39/118 ,  A61K2039/522 ,  A61K2039/5252 ,  A61K2039/5254 ,  A61K2039/552 ,  A61K2039/70 ,  C12N7/00 ,  C12N2710/16734 ,  C12N2710/24043 ,  C12N2740/13034 ,  C12N2750/14034 ,  C12N2770/16034 ,  C12N2770/16063

摘要： The present invention relates to improved inactivated feline calicivirus (FCV) vaccines. The invention also provides a process for producing stabilized inactivated FCV, and the use of such stabilized inactivated FCV, in the production of FCV immunogenic compositions. The invention further provides methods of inducing an immune response in an animal of the Felidae family, preferably a cat, using the immunogenic compositions according to the invention.

公开(公告)号：EP1734992A2

公开(公告)日：2006-12-27

申请号：EP05705920.6

申请日：2005-01-19

申请人： Merial Limited

发明人： POULET, Hervé ,  BARRAL, Denis

IPC分类号： A61K39/125 ,  C12Q1/70

CPC分类号： A61K39/12 ,  A61K39/118 ,  A61K2039/522 ,  A61K2039/5252 ,  A61K2039/5254 ,  A61K2039/552 ,  A61K2039/70 ,  C12N7/00 ,  C12N2710/16734 ,  C12N2710/24043 ,  C12N2740/13034 ,  C12N2750/14034 ,  C12N2770/16034 ,  C12N2770/16063

摘要： The present invention relates to improved inactivated feline calicivirus (FCV) vaccines. The invention also provides a process for producing stabilized inactivated FCV, and the use of such stabilized inactivated FCV, in the production of FCV immunogenic compositions. The invention further provides methods of inducing an immune response in an animal of the Felidae family, preferably a cat, using the immunogenic compositions according to the invention.

公开(公告)号：EP2734230A1

公开(公告)日：2014-05-28

申请号：EP12705199.3

申请日：2012-02-02

申请人： Merial Limited ,  Centre National de la Recherche Scientifique ,  Institut Gustave Roussy ,  Université Paris Sud

发明人： POULET, Hervé ,  HEIDMANN, Thierry

IPC分类号： A61K39/12 ,  C07K14/005 ,  C12N15/86

CPC分类号： C07K14/005 ,  A61K31/04 ,  A61K38/162 ,  A61K39/12 ,  A61K39/21 ,  A61K39/275 ,  A61K2039/5256 ,  A61K2039/53 ,  A61K2039/70 ,  A61K2300/00 ,  C07K14/15 ,  C12N7/00 ,  C12N15/86 ,  C12N2710/24043 ,  C12N2710/24044 ,  C12N2740/13022 ,  C12N2740/13034 ,  C12N2800/22

摘要： The present invention provides vectors that contain and express in vivo or in vitro FeLV antigens that elicit an immune response in animal or human against FeLV, compositions comprising said vectors and/or FeLV polypeptides, methods of vaccination against FeLV, and kits for use with such methods and compositions.

摘要翻译： 本发明提供载体，其含有体内或体外FeLV抗原，其在动物或人体内针对FeLV引起免疫应答，包含所述载体和/或FeLV多肽的组合物，针对FeLV的疫苗接种方法，以及用于其的试剂盒 方法和组成。

公开(公告)号：EP1248648B1

公开(公告)日：2012-01-11

申请号：EP01905858.5

申请日：2001-01-19

申请人： MERIAL

发明人： POULET, Hervé

IPC分类号： A61K39/245 ,  A61K39/39 ,  A61K39/295 ,  A61P31/22 ,  A61K39/23 ,  A61K39/235 ,  A61K39/175

CPC分类号： C12N7/00 ,  A61K39/12 ,  A61K39/245 ,  A61K39/39 ,  A61K2039/5252 ,  A61K2039/5254 ,  A61K2039/545 ,  A61K2039/552 ,  A61K2039/55505 ,  A61K2039/55511 ,  A61K2039/55566 ,  A61K2039/70 ,  C07K14/005 ,  C12N2710/16722 ,  C12N2710/16734 ,  C12N2710/16761

摘要： The invention concerns the use of a CHV antigen for preparing a vaccine against canine herpesvirus infection, to be administered to the pregnant bitch as close as possible to birth, preferably during the last third of pregnancy, and producing a high anti-CHV antibody rate in the pregnant bitch at the time of birth, inducing protection in the pups by antibody transfer during suckling. The invention also concerns an inactivated anti-CHV or subunit vaccine, useful for vaccinating pregnant females to protect pups by antibody transfer.

公开(公告)号：EP1846027A2

公开(公告)日：2007-10-24

申请号：EP06719132.0

申请日：2006-01-20

申请人： Merial Ltd.

发明人： POULET, Hervé ,  DAVID, Frederic Raymond

IPC分类号： A61K39/125 ,  A61K39/295 ,  A61K39/39 ,  A61P31/14 ,  C12N7/04

CPC分类号： A61K39/125 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/54 ,  A61K2039/545 ,  A61K2039/552 ,  A61K2039/55555 ,  A61K2039/55566 ,  C12N2770/16034

摘要： The present invention relates to improved methods and immunogenic and/or vaccine compositions for providing an immune response to feline calicivirus, including hypervirulent strains of feline calicivirus.

公开(公告)号：EP1194450A1

公开(公告)日：2002-04-10

申请号：EP00953242.5

申请日：2000-07-13

申请人： MERIAL

发明人： POULET, Hervé ,  GOUTEBROZE, Sylvain, Gabriel

IPC分类号： C07K16/10 ,  A61K39/12 ,  A61P31/14 ,  C12N5/12

CPC分类号： C12N7/00 ,  A61K39/12 ,  A61K39/125 ,  A61K2039/5252 ,  A61K2039/5254 ,  A61K2039/552 ,  A61K2039/55566 ,  C07K16/10 ,  C07K16/1009 ,  C12N2770/16034 ,  C12N2770/16061 ,  C12N2770/16063

摘要： The invention concerns immunogenic preparations and vaccines, in particular inactivated, efficient against feline calicivirus disease, based on strain 431 FCV virus as filed at the CNCM under access number CNCM I-2166, or one of its equivalents, in a carrier or excipient acceptable in veterinary medicine, preferably associated with the FCV virus derived from another FCV strain, in particular the G1 strain as filed at the CNCM under access number CNCM I-2167. The invention also concerns the hybridoma filed under access number CNCM I-2282, and the monoclonal antibody produced by said hybridoma.

公开(公告)号：EP2734230B1

公开(公告)日：2018-11-21

申请号：EP12705199.3

申请日：2012-02-02

申请人： Merial Limited ,  Centre National de la Recherche Scientifique ,  Institut Gustave Roussy ,  Université Paris-Sud

发明人： POULET, Hervé ,  HEIDMANN, Thierry

IPC分类号： A61K39/12 ,  C07K14/005 ,  C12N15/86

CPC分类号： C07K14/005 ,  A61K31/04 ,  A61K38/162 ,  A61K39/12 ,  A61K39/21 ,  A61K39/275 ,  A61K2039/5256 ,  A61K2039/53 ,  A61K2039/70 ,  A61K2300/00 ,  C07K14/15 ,  C12N7/00 ,  C12N15/86 ,  C12N2710/24043 ,  C12N2710/24044 ,  C12N2740/13022 ,  C12N2740/13034 ,  C12N2800/22

摘要： The present invention provides vectors that contain and express in vivo or in vitro FeLV antigens that elicit an immune response in animal or human against FeLV, compositions comprising said vectors and/or FeLV polypeptides, methods of vaccination against FeLV, and kits for use with such methods and compositions.

公开(公告)号：EP3156070A2

公开(公告)日：2017-04-19

申请号：EP16181806.7

申请日：2011-08-29

申请人： Merial Inc.

发明人： BUBLOT, Michel ,  REYNARD, Frederic ,  POULET, Hervé ,  DAVID, Frederic Raymond

IPC分类号： A61K39/145 ,  C07K14/035

CPC分类号： A61K39/17 ,  A61K39/12 ,  A61K39/245 ,  A61K2039/5256 ,  A61K2039/552 ,  C07K14/005 ,  C12N7/00 ,  C12N15/86 ,  C12N2710/16722 ,  C12N2710/16734 ,  C12N2760/18134 ,  C12N2760/18143 ,  C12N2760/18152

摘要： The present invention encompasses recombinant Newcastle Disease Virus - Herpesvirus vaccines or compositions. The invention encompasses recombinant NDV vectors encoding and expressing herpesvirus pathogen, antigens, proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals against disease.

公开(公告)号：EP1846027B1

公开(公告)日：2017-03-15

申请号：EP06719132.0

申请日：2006-01-20

申请人： Merial, Inc.

发明人： POULET, Hervé ,  DAVID, Frederic Raymond

IPC分类号： A61K39/00 ,  A61K39/12 ,  A61K39/125

CPC分类号： A61K39/125 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/54 ,  A61K2039/545 ,  A61K2039/552 ,  A61K2039/55555 ,  A61K2039/55566 ,  C12N2770/16034

公开(公告)号：EP2611460B1

公开(公告)日：2016-10-05

申请号：EP11752432.2

申请日：2011-08-29

申请人： Merial, Inc.

发明人： BUBLOT, Michel ,  REYNARD, Frederic ,  POULET, Hervé ,  DAVID, Frederic, Raymond

IPC分类号： A61K39/145 ,  C07K14/035

CPC分类号： A61K39/17 ,  A61K39/12 ,  A61K39/245 ,  A61K2039/5256 ,  A61K2039/552 ,  C07K14/005 ,  C12N7/00 ,  C12N15/86 ,  C12N2710/16722 ,  C12N2710/16734 ,  C12N2760/18134 ,  C12N2760/18143 ,  C12N2760/18152