公开(公告)号：EP1019510B1

公开(公告)日：2003-07-16

申请号：EP98946547.1

申请日：1998-10-01

申请人： MERIAL ,  The Queen's University of Belfast ,  The University of Saskatchewan

发明人： ALLAN, Gordon ,  MEEHAN, Brian ,  CLARK, Edward ,  ELLIS, John ,  HAINES, Deborah ,  HASSARD, Lori ,  HARDING, John ,  CHARREYRE, Catherine, Elisabeth ,  CHAPPUIS, Gilles, Emile ,  MCNEILLY, Francis

IPC分类号： C12N15/34 ,  C07K14/01 ,  A61K39/12 ,  A61K48/00 ,  C12Q1/68 ,  C07K16/08 ,  G01N33/53

CPC分类号： C07K14/005 ,  A23C19/0321 ,  A23C19/0323 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  A61K2039/51 ,  A61K2039/5252 ,  A61K2039/552 ,  A61K2039/55566 ,  C12N2750/10021 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/10043

摘要： The invention concerns porcine circovirus strains isolated from pulmonary and ganglionary specimens derived from livestock suffering from postweaning multisystemic wasting syndrome (PMWS). It concerns purified preparations of said strains, attenuated or inactivated standard vaccines, recombinant live vaccines, plasmid vaccines and subunit vaccines, as well as diagnostic reagents and methods. The invention also concerns DNA fragments useful for producing subunits in a expression vector in vitro or as sequences to be integrated in an expression vector in vivo of virus or plasmid type.

摘要翻译： 本发明涉及从患有断奶后多系统衰竭综合症（PMWS）的牲畜得到的肺和神经节样本分离的猪圆环病毒株。 它涉及所述菌株的纯化制剂，减毒或灭活的标准疫苗，重组活疫苗，质粒疫苗和亚单位疫苗以及诊断试剂和方法。 本发明还涉及可用于在体外表达载体中产生亚基的DNA片段或作为待整合入病毒或质粒类型的体内表达载体中的序列。

公开(公告)号：EP1019510A1

公开(公告)日：2000-07-19

申请号：EP98946547.1

申请日：1998-10-01

申请人： MERIAL ,  The Queen's University of Belfast ,  The University of Saskatchewan

发明人： ALLAN, Gordon ,  MEEHAN, Brian ,  CLARK, Edward ,  ELLIS, John ,  HAINES, Deborah ,  HASSARD, Lori ,  HARDING, John ,  CHARREYRE, Catherine, Elisabeth ,  CHAPPUIS, Gilles, Emile ,  MCNEILLY, Francis

IPC分类号： C12N15/34 ,  C07K14/01 ,  A61K39/12 ,  A61K48/00 ,  C12Q1/68 ,  C07K16/08 ,  G01N33/53

CPC分类号： C07K14/005 ,  A23C19/0321 ,  A23C19/0323 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  A61K2039/51 ,  A61K2039/5252 ,  A61K2039/552 ,  A61K2039/55566 ,  C12N2750/10021 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/10043

摘要： The invention concerns porcine circovirus strains isolated from pulmonary and ganglionary specimens derived from livestock suffering from postweaning multisystemic wasting syndrome (PMWS). It concerns purified preparations of said strains, attenuated or inactivated standard vaccines, recombinant live vaccines, plasmid vaccines and subunit vaccines, as well as diagnostic reagents and methods. The invention also concerns DNA fragments useful for producing subunits in a expression vector in vitro or as sequences to be integrated in an expression vector in vivo of virus or plasmid type.