Reaction cassette for performing sequential analytical assays by noncentrifugal and noncapillary manipulations
    1.
    发明公开
    Reaction cassette for performing sequential analytical assays by noncentrifugal and noncapillary manipulations 失效
    反应盒用于使用nichtzentrifugaler和nichtkapillarer操作顺序分析测定。

    公开(公告)号:EP0407827A2

    公开(公告)日:1991-01-16

    申请号:EP90112397.6

    申请日:1990-06-29

    申请人: MILES INC.

    IPC分类号: B01L3/00 G01N33/53

    摘要: Analytical reaction cassette and method for performing sequential analytical assay procedures to determine the amount of an analyte in a liquid test mixture. The reaction cassette (10) can be in the form of a substantially square container having a substantially horizontal axis of rotation and incorporated with one or more analytical reagents such that they are contacted with a liquid test mixture in a desired ordered sequence to perform a particular assay procedure. Corners (22-24) provided by the substantially square configuration of the reaction cassette disrupt the flow of liquids disposed in the reaction cassette upon contact therewith to thereby agitate and mix such liquids. A liquid disposed in the reaction cassette is capable of being manipulated and mixed therein by rotating the reaction cassette about the horizontal axis at sufficiently low velocities wherein the transport of such liquid is noncentrifugal and due substantially only to gravitational force. The reaction cassette is particularly useful for performing immunoturbidimetric assays, e.g., for the determination of glycated hemoglobin.

    摘要翻译: 分析反应盒和用于在液体测试混合物执行顺序分析测定程序,以确定一个矿井分析物的量的方法。 该反应盒可以是具有旋转的基本水平的轴线,并与一种或多种分析试剂寻求GDP是可以用在期望的有序序列的液体测试混合物以执行特定测定程序接触并入大致正方形容器的形式。 通过反应盒的大致正方形的配置提供角部破坏在反应盒时接触,从而搅拌并混合液体检查设置在它们的液体的流动。 在反应盒设置在液体能够被操纵的,并通过在足够低的速度绕水平轴的反应盒混入其中​​worin的液体输送仅到重力寻求非离心,并且由于基本上。 所述反应盒是用于执行测定免疫比浊,E. G.,糖化血红蛋白的测定是特别有用的。

    Reaction cassette for performing sequential analytical assays by noncentrifugal and noncapillary manipulations
    2.
    发明公开
    Reaction cassette for performing sequential analytical assays by noncentrifugal and noncapillary manipulations 失效
    用非执行和无机操作进行顺序分析测定的反应试剂

    公开(公告)号:EP0407827A3

    公开(公告)日:1992-09-02

    申请号:EP90112397.6

    申请日:1990-06-29

    申请人: MILES INC.

    IPC分类号: B01L3/00 G01N33/53

    摘要: Analytical reaction cassette and method for performing sequential analytical assay procedures to determine the amount of an analyte in a liquid test mixture. The reaction cassette (10) can be in the form of a substantially square container having a substantially horizontal axis of rotation and incorporated with one or more analytical reagents such that they are contacted with a liquid test mixture in a desired ordered sequence to perform a particular assay procedure. Corners (22-24) provided by the substantially square configuration of the reaction cassette disrupt the flow of liquids disposed in the reaction cassette upon contact therewith to thereby agitate and mix such liquids. A liquid disposed in the reaction cassette is capable of being manipulated and mixed therein by rotating the reaction cassette about the horizontal axis at sufficiently low velocities wherein the transport of such liquid is noncentrifugal and due substantially only to gravitational force. The reaction cassette is particularly useful for performing immunoturbidimetric assays, e.g., for the determination of glycated hemoglobin.