-
1.发明公开PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF 有权萨尔辛达维尔VERFAHREN ZUR HERSTELLUNG VON BENZIMIDAZOLDERIVATEN
公开(公告)号：EP2834224A2
公开(公告)日：2015-02-11
申请号：EP13772903.4
申请日：2013-04-01
申请人： MSN Laboratories Limited , Thirumalai Rajan, Srinivasan , Eswaraiah, Sajja , Raghuram, Suraparaju
IPC分类号： C07D277/64 , C07D235/14 , C07D409/06 , C07D209/14 , C07D495/04 , A61K31/425
CPC分类号： C07D401/12 , C07B2200/13 , C07D213/75 , C07D213/81 , Y10T428/2982
摘要： The present invention relates to novel salts of benzimidazole derivatives, preferably mesylate salt of benzimidazole derivatives which are useful intermediates in the synthesis of pure l-methyl-2-[N-[4-(N-n-hexyloxycarbonylamidino)phenyl]aminomethyl]benzimidazol-5-yl- carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide represented by the structural formula- 1 and its salts.
摘要翻译： 提供苯并咪唑衍生物的新型盐，优选苯并咪唑衍生物的盐，其是合成纯的1-甲基-2- [N- [4-（N，N-己氧羰基脒基）苯基]氨基甲基]苯并咪唑-5-基 - 羧酸的有用中间体 -N-（2-吡啶基）-N-（2-乙氧羰基乙基）酰胺及其盐。
-
2.发明公开PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE 审中-公开VERFAHREN ZUR HERSTELLUNG VON（R-）2-乙酰氨基-N-苄基-3-甲氧基丙酸
公开(公告)号：EP2534127A1
公开(公告)日：2012-12-19
申请号：EP11741981.2
申请日：2011-02-09
IPC分类号： C07C237/06 , C07C231/02 , C07C233/16 , C07C229/22
CPC分类号： C07C237/32 , C07C237/06 , C07C271/22
摘要： Processes for preparing and purifying (R)-2-acetamido-N-benzyl-3-methoxy- propionamide of formula-1 and intermediates thereof are provided.
摘要翻译： 提供了制备和纯化式-1的（R）-2-乙酰氨基-N-苄基-3-甲氧基 - 丙酰胺及其中间体的方法。
-
3.发明公开IMPROVED PROCESS FOR THE PREPARATION OF HIGHLY PURE (3R,5S)-7-Ý2-CYCLOPROPYL-4-(4-FLUOROPHENYL) QUINOLIN-3-YL¨-3,5-DIHYDROXY-6(E)-HEPTENOIC ACID AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF 审中-公开改进方法生产高纯（3R，5S）-7- [2-环丙基-4-（4-氟苯基）喹啉-3-基〕-3,5-二羟基-6-（E）庚烯酸和其可药用盐
公开(公告)号：EP2387561A2
公开(公告)日：2011-11-23
申请号：EP10738288.9
申请日：2010-01-18
IPC分类号： C07D215/12 , C07D215/14
CPC分类号： C07D215/14
摘要： Processes for preparing pravastatin, intermediates and pharmaceutically acceptable salts thereof are provided Crystalline forms of pravastatin, intermediates and pharmaceutically acceptable salts thereof are also disclosed.
-
公开(公告)号：EP2649060B1
公开(公告)日：2017-04-05
申请号：EP11847161.4
申请日：2011-12-07
发明人： SATYANARAYANA REDDY, Manne , NAGARAJU, Chakilam , THIRUMALAI RAJAN, Srinivasan , ESWARAIAH, Sajja , KODANDA RAMPRASAD, Achampeta , RAGHURAM, Suraparaju
IPC分类号： C07D401/02 , A61K31/4439 , A61P7/02
CPC分类号： C07D401/12 , C07D233/56
-
公开(公告)号：EP2649060A2
公开(公告)日：2013-10-16
申请号：EP11847161.4
申请日：2011-12-07
发明人： SATYANARAYANA REDDY, Manne , NAGARAJU, Chakilam , THIRUMALAI RAJAN, Srinivasan , ESWARAIAH, Sajja , KODANDA RAMPRASAD, Achampeta , RAGHURAM, Suraparaju
IPC分类号： C07D401/02 , A61K31/4439 , A61P7/02
CPC分类号： C07D401/12 , C07D233/56
摘要： The Present Invention Provides An Improved Process For The Preparation Of 1-methyl-2-[n-[4-(n-n-hexyloxycarbonylamidino) Phenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-n-(2-pyridyl)-n-(2-ethoxycarbonylethyl)amide Compound Of Formula-1 And Its Methanesulfonate Salt Compound Of Formula-1a.
-
6.发明公开IMPROVED PROCESSES FOR PREPARING PRASUGREL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEROEOF 审中-公开改进方法，其PRODUCING普拉格雷和药学上可接受的盐
公开(公告)号：EP2499147A2
公开(公告)日：2012-09-19
申请号：EP10821681.3
申请日：2010-10-07
发明人： SATYANARAYANA REDDY, Manne , THIRUMALAI RAJAN, Srinivasan , ESWARAIAH, Sajja , RAMA SUBBA REDDY, Karamala , KONDAL REDDY, Bairy , VENKAT REDDY, Ghojala
IPC分类号： C07D495/04 , A61K31/4365 , A61P7/02
CPC分类号： C07D495/04 , Y10T428/2982
摘要： Disclosed are improved processes for preparing prasugrel compound of formula-(1), its intermediates and pharmaceutically acceptable salts.
摘要翻译： 本发明公开了改进的方法用于制备式普拉格雷（1）化合物，其中间体及其药学上可接受的盐。
-
公开(公告)号：EP2240470A2
公开(公告)日：2010-10-20
申请号：EP09705099.1
申请日：2009-01-09
IPC分类号： C07D403/04
CPC分类号： C07D239/52 , C07D239/47
摘要： The present invention relates to an improved and novel process for the preparation of bosentan compound of formula (1). The present invention also relates to a crystalline form of bosentan and its intermediates.
-
公开(公告)号：EP2834224B1
公开(公告)日：2018-06-06
申请号：EP13772903.4
申请日：2013-04-01
申请人： MSN Laboratories Limited , Thirumalai Rajan, Srinivasan , Eswaraiah, Sajja , Raghuram, Suraparaju
IPC分类号： C07D277/64 , C07D235/14 , C07D409/06 , C07D209/14 , C07D495/04 , A61K31/425 , A61P7/02
CPC分类号： C07D401/12 , C07B2200/13 , C07D213/75 , C07D213/81 , Y10T428/2982
摘要： Provided are novel salts of benzimidazole derivatives, preferably salts of benzimidazole derivatives which are useful intermediates in the synthesis of pure 1-methyl-2-[N-[4-(N-n-hexyloxycarbonylamidino)phenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide and its salts.
-
9.发明授权PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF 有权三唑类抗真菌药物的制备方法，其中间体及其多晶型物
公开(公告)号：EP2758385B1
公开(公告)日：2018-03-28
申请号：EP12834181.5
申请日：2012-09-17
发明人： SATYANARAYANA, REDDY, Manne , THIRUMALAI RAJAN, Srinivasan , ESWARAIAH, Sajja , VISHNUVARDHAN, Sunkara
IPC分类号： C07D295/135 , C07D405/14 , C07D307/16 , C07D407/14 , C07D405/06 , A61K31/496 , A61P31/00
CPC分类号： C07D405/14 , C07B2200/07 , C07C51/09 , C07C51/487 , C07C59/66 , C07C67/08 , C07C67/31 , C07C67/60 , C07C211/27 , C07C241/04 , C07C251/76 , C07D263/24 , C07D263/26 , C07D307/24 , C07D413/06 , C07C243/28 , C07C69/734
摘要： A process for the preparation of 4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furanyl]methoxy]phenyl]-1-piperazinyl]phenyl]-2-[(1S,2S)-1-ethyl-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one compound of formula-1, its intermediates and polymorphs thereof. (I).
-
10.发明公开PROCESSES AND POLYMORPHS OF 5-[4-[4-(5-CYANO-1H-INDOL-3-YL) BUTYL]-1-PIPERAZINYL]-2-BENZOFURAN CARBOXAMIDE AND ITS SALTS 审中-公开VERFAHREN UND POLYMORPHE VON 5- [4- [4-（5-氰基-1H-吲哚-3-基）丁基] -1-哌嗪基] -2-苯并呋喃半胱氨酸在DESSEN SALZEN
公开(公告)号：EP2900658A2
公开(公告)日：2015-08-05
申请号：EP13842370.2
申请日：2013-09-26
申请人： MSN Laboratories Limited , Thirumalai Rajan, Srinivasan , Eswaraiah, Sajja , Vishnuvardhan, Sunkara
IPC分类号： C07D405/14 , C07D209/10 , A61K31/496
CPC分类号： C07D405/12
摘要： The present invention relates to an improved process for the preparation of antidepressant drug i.e., 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofuran carboxamide hydrochloride compound of formula- la represented by the following structural formula: (1a)
摘要翻译： 本发明涉及制备抗抑郁药的改进方法，即5- [4- [4-（5-氰基-1H-吲哚-3-基）丁基] -1-哌嗪基] -2-苯并呋喃甲酰胺盐酸盐 由以下结构式表示的式-a化合物：（1a）
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.016 秒)
