专利检索 ap:("MedImmune, LLC" OR "Humabs Biomed SA") AND inv:"WANG, Qun" 第 1 页

1.

发明公开
ANTI-O1 ANTIBODIES AND USES THEREOF 审中-公开

公开(公告)号：EP3529273A1

公开(公告)日：2019-08-28

申请号：EP17861658.7

申请日：2017-10-16

申请人： MedImmune, LLC , Humabs Biomed SA

发明人： WANG, Qun , STOVER, Charles K. , PENNINI, Meghan , CHANG, Chew-Shun , XIAO, Xiaodong , HILLIARD, Jamese , KAPLAN, Gilad , CORTI, Davide , CAMERONI, Elisabetta , BELTRAMELLO, Martina

IPC分类号： C07K16/12 , A61K39/395 , A61K39/40

2.

发明公开
ANTI-O2 ANTIBODIES AND USES THEREOF 审中-公开

公开(公告)号：EP3496748A1

公开(公告)日：2019-06-19

申请号：EP17837753.7

申请日：2017-08-04

申请人： Medimmune, LLC , Humabs Biomed SA

发明人： WANG, Qun , STOVER, Charles, K. , PENNINI, Meghan , XIAO, Xiaodong , CORTI, Davide , CAMERONI, Elisabetta , BELTRAMELLO, Martina , KAPLAN, Gilad , DEMARCO, Anna

IPC分类号： A61K39/02 , A61K39/108 , A61K39/395 , A61K39/40 , A61K31/715 , C12P21/08

3.

发明公开
SYNTHETIC OLIGOSACCHARIDE SUBUNITS OF THE PSL EXOPOLYSACCHARIDE OF PSEUDOMONAS AERUGINOSA AND USES THEROF 审中-公开
标题翻译：合成OLIGOSACCHARIDUNTEREINHEITEN绿脓杆菌的PSL胞外多糖及其用途

公开(公告)号：EP3001838A2

公开(公告)日：2016-04-06

申请号：EP14797588.2

申请日：2014-05-13

申请人： MedImmune, LLC , University of Georgia Research Foundation, Inc.

发明人： DIGIANDOMENICO, Antonio , WANG, Qun , STOVER, Charles, K. , BOONS, Geert-Jan , MO, Kai-for , LI, Huiqing

IPC分类号： C07K16/12

CPC分类号： C08B37/0006 , A61K39/104 , A61K47/48284 , A61K47/4833 , A61K47/643 , A61K47/646 , A61K2039/6081 , C07H15/04 , G01N33/5308 , G01N33/56911 , G01N2333/21 , G01N2400/00 , G01N2400/02 , G01N2400/38 , G01N2500/04

摘要： This disclosure relates to synthetic oligosaccharide subunits of the Pseudomonas exosaccharide Psl and uses thereof, e.g, for epitope mapping of anti-Psl antibodies, for identification of anti-Psl antibodies, and for use as vaccines.

4.

发明公开
MRKA POLYPEPTIDES, ANTIBODIES, AND USES THEREOF 审中-公开

公开(公告)号：EP3341004A1

公开(公告)日：2018-07-04

申请号：EP16839995.4

申请日：2016-08-23

申请人： Medimmune, LLC

发明人： WANG, Qun , RAJAN, Saravanan , CHANG, Chew-Shun , HEIDBRINK THOMPSON, Jenny , LIN, Hung-Yu , STOVER, Charles Kendall , PENNINI, Meghan , DALL'ACQUA, William , CHOWDHURY, Partha S. , XIAO, Xiaodong

IPC分类号： A61K38/00 , A61K39/108 , A61K39/395 , C07K14/26 , C07K16/12 , C07K16/18

CPC分类号： C07K16/1228 , A61K39/0266 , A61K2039/545 , A61K2039/55566 , C07K2317/76 , C07K2317/92

摘要： The present disclosure provides MrkA binding proteins, e.g., antibodies or antigen binding fragments thereof that bind to MrkA and induce opsonophagocytic killing of Klebsiella (e.g., Klebsiella pneumoniae). The present disclosure also provides methods of reducing Klebsiella (e.g., Klebsiella pneumoniae) or treating or preventing Klebsiella (e.g., Klebsiella pneumoniae) infection in a subject comprising administering MrkA binding proteins, e.g., antibodies or antigen-binding fragments thereof, MrkA polypeptides, immunogenic fragments thereof, or polynucleotides encoding MrkA or immunogenic fragments thereof to the subject.