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公开(公告)号:EP3372674A1
公开(公告)日:2018-09-12
申请号:EP16862024.3
申请日:2016-10-31
摘要: The present invention provides a method for producing platelets, including the step of culturing megakaryocyte cells in a culture solution in a culture vessel, wherein in the culturing step, the culture solution is stirred by a stirring blade moving reciprocally.
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公开(公告)号:EP3372674B1
公开(公告)日:2020-10-07
申请号:EP16862024.3
申请日:2016-10-31
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公开(公告)号:EP3351627A1
公开(公告)日:2018-07-25
申请号:EP16846363.6
申请日:2016-09-08
CPC分类号: C12N5/0644 , A61K35/14 , A61K35/19 , C12M3/00 , C12N2506/13 , C12N2527/00
摘要: The present invention provides a method for producing platelets, and the method comprises a step of culturing megakaryocytes in a culture solution in a culture vessel, wherein the culture solution is stirred with a stirrer in the culture step.
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公开(公告)号:EP3950921A1
公开(公告)日:2022-02-09
申请号:EP20778817.5
申请日:2020-03-24
发明人: HIGUCHI, Akira , NAITO, Hiroyuki , OKAMOTO, Haruki
摘要: A cell suspension treatment apparatus has a circulation circuit and a filling liquid supply source that supplies a filling liquid to the circulation circuit. The circulation circuit includes a hollow fiber membrane filter, a reservoir, a pump that is provided on a downstream side of the reservoir and on an upstream side of the hollow fiber membrane filter, and a valve that is provided on the downstream side of the reservoir and on an upstream side of the pump. The filling liquid supply source is connected to a portion of the circulation circuit between the first valve and the pump. After the concentrated cell suspension is stored in the reservoir, in a state where the valve is closed and the pump is driven, the filling liquid supply source starts supplying the filling liquid to the circulation circuit to push the cell suspension, which remains in a portion of the circulation circuit from the pump to the inlet port of the reservoir, to flow toward the reservoir by the filling liquid.
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公开(公告)号:EP3680325A1
公开(公告)日:2020-07-15
申请号:EP18859680.3
申请日:2018-09-19
摘要: The present invention provides a method for producing platelets that can improve at least one of the ability of megakaryocyte to produce platelets and the bioactivity of platelets produced even in high-density culture, for example. The method for producing platelets of the present invention includes a platelet producing step of producing platelets from megakaryocytes, wherein the platelet producing step is performed in the presence of at least one of glycine and cysteine.
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