公开(公告)号：EP1631568A1

公开(公告)日：2006-03-08

申请号：EP04759965.9

申请日：2004-04-16

申请人： Memory Pharmaceuticals Corporation

发明人： HOPPER, Allen ,  KUESTER, Erik ,  DUNN, Robert ,  CONTICELLO, Richard

IPC分类号： C07D407/12 ,  C07D407/04 ,  C07D403/04 ,  C07D231/12 ,  A61K31/4155 ,  A61P25/00

CPC分类号： C07D403/04 ,  C07D231/12 ,  C07D231/56 ,  C07D307/20 ,  C07D405/04 ,  C07D405/12 ,  C07D409/12

摘要： Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.