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公开(公告)号：EP1581215B1
公开(公告)日：2010-02-17
申请号：EP03789341.9
申请日：2003-12-18
申请人： Merck Patent GmbH
发明人： AUTIER, Valérie , ARBELLOT DE VACQUEUR, Annick , MOINET, Gérard , MARAIS, Dominique , KARGAR, Catherine , KERGOAT, Micheline
IPC分类号： A61K31/194 , A61K31/235 , A61P3/10 , C07C321/26
CPC分类号： A61K45/06 , A61K31/00 , A61K31/06 , A61K31/19 , A61K31/192 , A61K31/194 , A61K31/216 , A61K31/22 , A61K31/235 , A61K31/426 , A61K31/55 , A61K2300/00
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公开(公告)号：EP1581215A1
公开(公告)日：2005-10-05
申请号：EP03789341.9
申请日：2003-12-18
申请人： Merck Patent GmbH
发明人： AUTIER, Valérie , ARBELLOT DE VACQUEUR, Annick , MOINET, Gérard , MARAIS, Dominique , KARGAR, Catherine , KERGOAT, Micheline
IPC分类号： A61K31/426 , A61K31/194 , A61K31/235 , A61P3/10 , C07C321/26
CPC分类号： A61K45/06 , A61K31/00 , A61K31/06 , A61K31/19 , A61K31/192 , A61K31/194 , A61K31/216 , A61K31/22 , A61K31/235 , A61K31/426 , A61K31/55 , A61K2300/00
摘要： The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase for the preparation of a medicament for the prevention and/or treatment of diabetes.
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3.发明授权USE OF 4-OXOBUTANOIC ACID DERIVATIVES IN THE TREATMENT OF PATHOLOGIES ASSOCIATED WITH IMMUNOLOGICAL DISORDERS 有权4-氧代衍生物在疾病治疗的免疫学LEIDEN相关的使用
公开(公告)号：EP2214659B1
公开(公告)日：2011-08-31
申请号：EP08856548.6
申请日：2008-11-06
申请人： Merck Patent GmbH
IPC分类号： A61K31/192 , A61K31/341 , A61K31/36 , A61P37/06 , A61P37/02 , A61P1/06 , A61P19/02 , A61P17/06 , A61P7/06 , A61P35/00
CPC分类号： A61K31/192 , A61K31/341 , A61K31/36
摘要： The present invention relates to the use of a 4-oxobutanoic acid derivative for the preparation of a pharmaceutical composition for the treatment of pathologies associated with immunological disorders.
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4.发明公开USE OF 4-OXOBUTANOIC ACID DERIVATIVES IN THE TREATMENT OF PATHOLOGIES ASSOCIATED WITH IMMUNOLOGICAL DISORDERS 有权4-氧代衍生物在疾病治疗的免疫学LEIDEN相关的使用
公开(公告)号：EP2214659A1
公开(公告)日：2010-08-11
申请号：EP08856548.6
申请日：2008-11-06
申请人： Merck Patent GmbH
IPC分类号： A61K31/192 , A61K31/341 , A61K31/36 , A61P37/06 , A61P37/02 , A61P1/06 , A61P19/02 , A61P17/06 , A61P7/06 , A61P35/00
CPC分类号： A61K31/192 , A61K31/341 , A61K31/36
摘要： The present invention relates to the use of a 4-oxobutanoic acid derivative for the preparation of a pharmaceutical composition for the treatment of pathologies associated with immunological disorders.
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5.发明公开KYNURENINE 3-HYDROXYLASE INHIBITORS FOR THE TREATMENT OF DIABETES BY INCREASING THE NUMBER OF ISLETS OF LANGERHANS CELLS 审中-公开犬尿氨酸3-羟化酶抑制剂用于糖尿病的治疗通过增加朗格汉斯群岛数
公开(公告)号：EP1581216A1
公开(公告)日：2005-10-05
申请号：EP03814462.2
申请日：2003-12-18
申请人： Merck Patent GmbH
发明人： KERGOAT, Micheline , KARGAR, Catherine , AUTIER, Valérie , ARBELLOT DE VACQUEUR, Annick , MOINET, Gérard , MARAIS, Dominique
IPC分类号： A61K31/426 , A61K31/194 , A61K31/235 , A61P3/10
CPC分类号： A61K45/06 , A61K31/00 , A61K31/06 , A61K31/19 , A61K31/192 , A61K31/194 , A61K31/216 , A61K31/22 , A61K31/235 , A61K31/426 , A61K31/55 , A61K2300/00
摘要： The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase, for the preparation of a medica ment for increasing the number of islets of Langerhans cells, which is intended especially for the prevention and/or treatment of diabetes.
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