公开(公告)号：EP2525659A1

公开(公告)日：2012-11-28

申请号：EP11735040.5

申请日：2011-01-18

申请人： Merck Sharp & Dohme Corp.

发明人： SIDDIQUI, M. Arshad ,  NAN, Yang ,  PATEL, Mehul, F. ,  REDDY, Panduranga Adulla P. ,  MANSOOR, Umar Faruk ,  MENG, Zhaoyang ,  VITHARANA, Lalanthi Dilrukshi ,  ZHAO, Lianyun ,  MANDAL, Amit, K. ,  LIU, Duan ,  TANG, Shuyi ,  MCRINER, Andrew ,  BELANGER, David, B. ,  CURRAN, Patrick, J. ,  DAI, Chaoyang ,  ANGELES, Angie, R. ,  YANG, Liping ,  DANIELS, Matthew Hersh

IPC分类号： A01N43/90

CPC分类号： C07D471/08 ,  C07D487/04 ,  C07D487/08 ,  C07D491/147 ,  C07D498/08 ,  C07D513/08 ,  C07D519/00

摘要： The present invention provides Pyrazolopyrimidine Compounds of Formula (I): wherein L, T, Z, U, V, W, R3, R6, R7, R8, and m are as defined herein, and pharmaceutically acceptable salts of such Pyrazolopyrimidine Compounds. The Pyrazolopyrimidine Compounds are useful in the treatment of cancer and other diseases or disorders wherein mTOR is deregulated.

公开(公告)号：EP2525659B1

公开(公告)日：2019-02-27

申请号：EP11735040.5

申请日：2011-01-18

申请人： Merck Sharp & Dohme Corp.

发明人： SIDDIQUI, M. Arshad ,  NAN, Yang ,  PATEL, Mehul, F. ,  REDDY, Panduranga Adulla P. ,  MANSOOR, Umar Faruk ,  MENG, Zhaoyang ,  VITHARANA, Lalanthi Dilrukshi ,  ZHAO, Lianyun ,  MANDAL, Amit, K. ,  LIU, Duan ,  TANG, Shuyi ,  MCRINER, Andrew ,  BELANGER, David, B. ,  CURRAN, Patrick, J. ,  DAI, Chaoyang ,  ANGELES, Angie, R. ,  YANG, Liping ,  DANIELS, Matthew Hersh

IPC分类号： A01N43/90