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Patent Agency Ranking
公开(公告)号：EP2900223A1
公开(公告)日：2015-08-05
申请号：EP13841687.0
申请日：2013-09-26
Applicant: Merck Sharp & Dohme Corp.
Inventor： WILSON, Kevin, J. , WITTER, David, J. , DANIELS, Matthew, H. , ANGELES, Angie, R. , SILIPHAIVANH, Phieng , SLOMAN, David , O'BOYLE, Brendan , FALCONE, Danielle , WHITE, Catherine , FERGUSON, Ron , ZHOU, Wei , LIPFORD, Kathryn , MANSOOR, Umar Faruk , FEVRIER, Salem , HUANG, Xianhai , KURUKULASURIYA, Ravi , RICHARD, Judson, E. , TANG, Shuyi , BOYCE, Christopher , KOZLOWSKI, Joseph , BAKSHI, Raman Kumar , KARUNAKARAN, Ganesh Babu
IPC: A61K9/66 , A61K31/00 , A61K31/4545
CPC classification number: A61K31/437 , A61K31/4545 , A61K45/06 , C07D471/04
Abstract: Disclosed are the ERK inhibitors of formula (1.0), having a pyrazolopyridine base structure, and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds offormula (1.0).
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2.发明授权SPIRO-CONDENSED 1, 3, 4-THIADIAZOLE DERIVATIVES FOR INHIBITING KSP KINESIN ACTIVITY 有权螺稠-1,3,4-噻二唑用于抑制KSP驱动蛋白活性
公开(公告)号：EP2220061B1
公开(公告)日：2016-02-17
申请号：EP08839917.5
申请日：2008-10-16
Applicant: Merck Sharp & Dohme Corp.
Inventor： SIDDIQUI, M. Arshad , DAI, Chaoyang , MANSOOR, Umar, Faruk , YANG, Liping , VITHARANA, Lalalnthi, Dilrukshi , ANGELES, Angie, R.
IPC: C07D285/14 , C07D515/10 , C07D515/20 , A61K31/433 , A61P35/00
CPC classification number: C07D211/14 , C07D285/14 , C07D471/04 , C07D515/10 , C07D515/20
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公开(公告)号：EP2900223B1
公开(公告)日：2017-10-25
申请号：EP13841687.0
申请日：2013-09-26
Applicant: Merck Sharp & Dohme Corp.
Inventor： WILSON, Kevin, J. , WITTER, David, J. , DANIELS, Matthew, H. , ANGELES, Angie, R. , SILIPHAIVANH, Phieng , SLOMAN, David , O'BOYLE, Brendan , FALCONE, Danielle , WHITE, Catherine , FERGUSON, Ron , ZHOU, Wei , LIPFORD, Kathryn , MANSOOR, Umar Faruk , FEVRIER, Salem , HUANG, Xianhai , KURUKULASURIYA, Ravi , RICHARD, Judson, E. , TANG, Shuyi , BOYCE, Christopher , KOZLOWSKI, Joseph , BAKSHI, Raman Kumar , KARUNAKARAN, Ganesh Babu
IPC: C07D471/04 , A61K31/437 , A61P35/00
CPC classification number: A61K31/437 , A61K31/4545 , A61K45/06 , C07D471/04
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公开(公告)号：EP2525659A1
公开(公告)日：2012-11-28
申请号：EP11735040.5
申请日：2011-01-18
Applicant: Merck Sharp & Dohme Corp.
Inventor： SIDDIQUI, M. Arshad , NAN, Yang , PATEL, Mehul, F. , REDDY, Panduranga Adulla P. , MANSOOR, Umar Faruk , MENG, Zhaoyang , VITHARANA, Lalanthi Dilrukshi , ZHAO, Lianyun , MANDAL, Amit, K. , LIU, Duan , TANG, Shuyi , MCRINER, Andrew , BELANGER, David, B. , CURRAN, Patrick, J. , DAI, Chaoyang , ANGELES, Angie, R. , YANG, Liping , DANIELS, Matthew Hersh
IPC: A01N43/90
CPC classification number: C07D471/08 , C07D487/04 , C07D487/08 , C07D491/147 , C07D498/08 , C07D513/08 , C07D519/00
Abstract: The present invention provides Pyrazolopyrimidine Compounds of Formula (I): wherein L, T, Z, U, V, W, R3, R6, R7, R8, and m are as defined herein, and pharmaceutically acceptable salts of such Pyrazolopyrimidine Compounds. The Pyrazolopyrimidine Compounds are useful in the treatment of cancer and other diseases or disorders wherein mTOR is deregulated.
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公开(公告)号：EP2525659B1
公开(公告)日：2019-02-27
申请号：EP11735040.5
申请日：2011-01-18
Applicant: Merck Sharp & Dohme Corp.
Inventor： SIDDIQUI, M. Arshad , NAN, Yang , PATEL, Mehul, F. , REDDY, Panduranga Adulla P. , MANSOOR, Umar Faruk , MENG, Zhaoyang , VITHARANA, Lalanthi Dilrukshi , ZHAO, Lianyun , MANDAL, Amit, K. , LIU, Duan , TANG, Shuyi , MCRINER, Andrew , BELANGER, David, B. , CURRAN, Patrick, J. , DAI, Chaoyang , ANGELES, Angie, R. , YANG, Liping , DANIELS, Matthew Hersh
IPC: A01N43/90
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