专利检索 ap:("Merck Sharp & Dohme Corp.") AND inv:"MULHEARN, James, J." 第 1 页

1.

发明公开
3-ARYL AND HETEROARYL SUBSTITUTED 5-TRIFLUOROMETHYL OXADIAZOLES AS HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS 审中-公开

公开(公告)号：EP3475275A1

公开(公告)日：2019-05-01

申请号：EP17815984.4

申请日：2017-06-19

申请人： Merck Sharp & Dohme Corp.

发明人： WALJI, Abbas , BERGER, Richard , STUMP, Craig, A. , SCHLEGEL, Kelly Ann, S. , MULHEARN, James, J. , GRESHOCK, Thomas, J. , WANG, Deping , FRALEY, Mark, E. , JONES, Kristen, G.

IPC分类号： C07D413/14 , A61K31/4245 , A61K31/444

2.

发明公开
PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS 审中-公开

公开(公告)号：EP3407916A2

公开(公告)日：2018-12-05

申请号：EP17744740.6

申请日：2017-01-24

申请人： Merck Sharp & Dohme Corp.

发明人： GARBACCIO, Robert, M. , KERN, Jeffrey, C. , MULHEARN, James, J. , BRANDISH, Philip, E.

IPC分类号： A61K47/00 , A61K47/06 , A61K47/24

CPC分类号： A61K47/6849 , A61K47/6803 , A61K47/6889

摘要： Phosphonate linkers and their use for delivering compounds with passive cell permeability into a cell wherein the phosphonate group facilitateS cellular retention of the compound are described.