专利检索 ap:("Merck Sharp & Dohme Corp.") AND inv:"WANG, Xiu" 第 1 页

1.

发明授权
BICYCLOAMINE-SUBSTITUTED-N-BENZENESULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS 有权

公开(公告)号：EP3074402B1

公开(公告)日：2019-01-16

申请号：EP14866477.4

申请日：2014-11-24

申请人： Merck Sharp & Dohme Corp.

发明人： LI, Dansu , LAYTON, Mark E. , ROECKER, Anthony J. , EGBERTSON, Melissa , JONES, Kristen L. G. , WANG, Xiu , PENG, Xuanjia

IPC分类号： C07D487/04 , C07D491/20 , C07D471/04 , C07D455/02 , A61K31/433 , A61K31/427 , A61K31/4439 , A61K31/506 , A61K31/501 , A61K31/437 , A61K31/4375 , A61P25/02

2.

发明公开
HYDROXYPYRROLIDINE-SUBSTITUTED ARYLSULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS 审中-公开

公开(公告)号：EP3983414A1

公开(公告)日：2022-04-20

申请号：EP20822235.6

申请日：2020-06-08

申请人： Merck Sharp & Dohme Corp.

发明人： ROECKER, Anthony, J. , LAYTON, Mark, E. , WANG, Deping , WANG, Xiu , PENG, Xuanjia

IPC分类号： C07D487/04 , C07D471/04 , C07D285/135

3.

发明公开
BICYCLOAMINE-SUBSTITUTED-N-BENZENESULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS 审中-公开
标题翻译：选择性活动BICYCLOAMINSUBSTITUIERTE的N-苯磺酰胺压控钠通道

公开(公告)号：EP3074402A1

公开(公告)日：2016-10-05

申请号：EP14866477.4

申请日：2014-11-24

申请人： Merck Sharp & Dohme Corp.

发明人： LI, Dansu , LAYTON, Mark E. , ROECKER, Anthony J. , EGBERTSON, Melissa , JONES, Kristen L. G. , WANG, Xiu , PENG, Xuanjia

IPC分类号： C07D487/04

CPC分类号： C07D487/04 , C07D213/76 , C07D237/20 , C07D239/42 , C07D277/52 , C07D285/135 , C07D471/04 , C07D487/10 , C07D491/20

摘要： Disclosed are compounds of Formula A-a, or a salt thereof: Where "B
1 " and "R
1 " through "R
5 " are as defined herein, which compounds have properties for blocking Na
v 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A-a or their salts, and methods of treating neuropathic pain disorders using the same.